Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lee G. Gisclon"'
Autor:
Barry Hafkin, Jaya Natarajan, R. Rex Williams, Cynthia L. Fowler, Lee G. Gisclon, Christopher R. Curtin
Publikováno v:
The Journal of Clinical Pharmacology. 37:744-750
A randomized, placebo-controlled, two-way crossover study in 16 healthy men was performed to determine the effect of orally administered levofloxacin at steady-state conditions, given at 500 mg every 12 hours, on the pharmacokinetics of theophylline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecd6645535d836a7cfcce4c40b14a8e
https://doi.org/10.1002/j.1552-4604.1997.tb04362.x
https://doi.org/10.1002/j.1552-4604.1997.tb04362.x
Autor:
Christopher R. Curtin, Terry E O’Reilly, Lee G. Gisclon, Angela J Bowen, Dorothy Lakewold, Frankie A. Wong, Kathy L Larson, Sally A Palmer, Jaya Natarajan
Publikováno v:
Arzneimittel-Forschung. 50(10)
Two open-label, randomized studies determined the bioequivalence of a test preparation (Prefest) of micronized 17 beta-estradiol (E2, CAS 50-28-2) tablets as compared with a reference preparation of micronized E2 tablets in healthy postmenopausal wom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cfb61a89caaf8551665720d76e74ee
https://pubmed.ncbi.nlm.nih.gov/11105233
https://pubmed.ncbi.nlm.nih.gov/11105233
Autor:
Christopher R. Curtin, Frankie A. Wong, K. L. Larson, D. N. Morrison, Jaya Natarajan, Lee G. Gisclon, D. Bourg
Publikováno v:
Journal of clinical pharmacology. 40(7)
The effect of a high-fat meal on the absorption and pharmacokinetics of 17 beta-estradiol (E2), estrone (E1), estrone sulfate (E1S), and 17-deacetylnorgestimate (17d-NGM) were determined in this two-way complete crossover study of a single dose of E2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37ede065230a9084a014d5694cd6e22
https://pubmed.ncbi.nlm.nih.gov/10883418
https://pubmed.ncbi.nlm.nih.gov/10883418
Autor:
Cornelia Baldauf, Lee G. Gisclon, Cornelis H. Kleinbloesem, Yousif Al-Hamdan, F. Brunner-Ferber, Keith Wesnes, Françoise Jaquet-Müller, Sally A. Walker, R. John Stubbs, Christopher R. Curtin
Publikováno v:
Clinical pharmacology and therapeutics. 59(6)
Objectives Mazapertine is a structurally novel antipsychotic compound with high affinity for D2, D3, 5-HT1a, and α1 receptors. The objectives were to determine whether tolerance to orthostatic hypotension caused by this compound could be induced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411217be1c0568d57de8391adf5b3747
https://pubmed.ncbi.nlm.nih.gov/8681493
https://pubmed.ncbi.nlm.nih.gov/8681493
Publikováno v:
American Journal of Physiology-Renal Physiology. 253:F141-F150
Experiments were conducted to study the transport of the histamine H2-receptor antagonist, cimetidine, in luminal membrane vesicles prepared from rabbit renal cortex. Cimetidine accumulated in the vesicles with time. Cimetidine uptake was sensitive t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7b65220177332986a60d247ff3b8a7
https://doi.org/10.1152/ajprenal.1987.253.1.f141
https://doi.org/10.1152/ajprenal.1987.253.1.f141
Publikováno v:
Clinical Pharmacology and Therapeutics. 45:444-452
It is generally assumed that the systems involved in the transport of organic cations and organic anions in the renal proximal tubule are substrate selective (i.e., organic anions do not inhibit organic cation transport and vice versa). However, rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f54fdd8f22b313b5c8414ca3fa10bb
https://doi.org/10.1038/clpt.1989.53
https://doi.org/10.1038/clpt.1989.53
Publikováno v:
American Journal of Health-System Pharmacy. 36:1179-1184
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::052ed9325810f4dd86d3c5609138b3ad
https://doi.org/10.1093/ajhp/36.9.1179
https://doi.org/10.1093/ajhp/36.9.1179
Publikováno v:
Pharmaceutical Research. :465-471
The development of new methods to study transport processes in renal epithelia has greatly enhanced our knowledge of the mechanisms involved in the transport of a number of endogenous compounds. More recently, these methods have been applied to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::082f14cbee18780f71cebb33a4c93c88
https://doi.org/10.1023/a:1015904905235
https://doi.org/10.1023/a:1015904905235
Publikováno v:
The American journal of physiology. 254(1 Pt 2)
It is generally assumed that the organic cation transport system in the renal proximal tubule is specific for organic cations and the transport of organic cations is not affected by organic anions. However, there are also data in the literature demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7961a02282d2f007c1bbe6e163a9e4
https://pubmed.ncbi.nlm.nih.gov/2962517
https://pubmed.ncbi.nlm.nih.gov/2962517