Multi-modal analysis reveals tumor and immune features distinguishing EBV-positive and EBV-negative post-transplant lymphoproliferative disorders.

Autor: Toh J; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA; PhD Program in Immunology, Stanford University School of Medicine, Stanford, CA, USA; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA; Center for Biomedical Informatics Research, Department of Medicine, Stanford University, Stanford, CA, USA., Reitsma AJ; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA., Tajima T; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA., Younes SF; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Ezeiruaku C; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA., Jenkins KC; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA., Peña JK; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA; PhD Program in Immunology, Stanford University School of Medicine, Stanford, CA, USA., Zhao S; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Wang X; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA., Lee EYZ; PhD Program in Stem Cell and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA., Glass MC; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA., Kalesinskas L; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA; Center for Biomedical Informatics Research, Department of Medicine, Stanford University, Stanford, CA, USA; PhD Program in Biomedical Informatics, Stanford University School of Medicine, Stanford, CA, USA., Ganesan A; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA; Center for Biomedical Informatics Research, Department of Medicine, Stanford University, Stanford, CA, USA; Institute for Computational and Mathematical Engineering, School of Engineering, Stanford University, Stanford, CA, USA., Liang I; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA., Pai JA; PhD Program in Immunology, Stanford University School of Medicine, Stanford, CA, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Harden JT; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA; PhD Program in Immunology, Stanford University School of Medicine, Stanford, CA, USA., Vallania F; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA; Center for Biomedical Informatics Research, Department of Medicine, Stanford University, Stanford, CA, USA., Vizcarra EA; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA., Bhagat G; Department of Pathology, Columbia University, New York, NY, USA., Craig FE; Laboratory of Medicine and Pathology, Mayo Clinic Arizona, Scottsdale, AZ, USA., Swerdlow SH; Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Morscio J; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium., Dierickx D; Department of Hematology, University Hospitals Leuven, and the Laboratory for Experimental Hematology, Department of Oncology, University of Leuven, Leuven, Belgium., Tousseyn T; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium; Department of Pathology, University Hospitals Leuven, Leuven, Belgium., Satpathy AT; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA; Stanford Immunology, Stanford University School of Medicine, Stanford, CA, USA., Krams SM; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA; Stanford Immunology, Stanford University School of Medicine, Stanford, CA, USA., Natkunam Y; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Khatri P; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA; Center for Biomedical Informatics Research, Department of Medicine, Stanford University, Stanford, CA, USA; Stanford Immunology, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: pkhatri@stanford.edu., Martinez OM; Department of Surgery, Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA, USA; Stanford Immunology, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: omm@stanford.edu.

Publikováno v: Cell reports. Medicine [Cell Rep Med] 2024 Dec 17; Vol. 5 (12), pp. 101851. Date of Electronic Publication: 2024 Dec 09.