Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lee E. Vandivier"'
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100901- (2021)
Summary: Eukaryotic RNAs can be modified with a non-canonical 5′ nicotinamide adenine dinucleotide (NAD+) cap. NAD-seq identifies transcriptome-wide NAD+ capped RNAs. NAD-seq takes advantage of click chemistry to allow the capture of NAD+ capped RN
Externí odkaz:
https://doaj.org/article/e3b2951872f144749e381e62ce4ac686
Autor:
Marianne C. Kramer, Kevin A. Janssen, Kyle Palos, Andrew D. L. Nelson, Lee E. Vandivier, Benjamin A. Garcia, Eric Lyons, Mark A. Beilstein, Brian D. Gregory
Publikováno v:
Plant Direct, Vol 4, Iss 7, Pp n/a-n/a (2020)
Abstract After transcription, a messenger RNA (mRNA) is further post‐transcriptionally regulated by several features including RNA secondary structure and covalent RNA modifications (specifically N6‐methyladenosine, m6A). Both RNA secondary struc
Externí odkaz:
https://doaj.org/article/80905837322145e8b608b1550305e467
Autor:
Ashley Maillet, Fei Liu, Chao Fang, Jinxing Li, Neil Kubica, Lars Kolster Petersen, Donovan N. Chin, Nils Jakob Vest Hansen, Luis A. Barrera, Jenifer B Kaplan, Herschel Mukherjee, Gnanasambandam Kumaravel, J Craig Blain, Lee E Vandivier, Jessica E. Friedman, Allan Beck Christensen, David M. Chenoweth, Jennifer C. Petter
Publikováno v:
ACS Chemical Biology. 15:2374-2381
RNA is emerging as a valuable target for the development of novel therapeutic agents. The rational design of RNA-targeting small molecules, however, has been hampered by the relative lack of methods for the analysis of small molecule-RNA interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7520d11f7303715e89e8764fd08c5649
https://doi.org/10.1021/acschembio.0c00357
https://doi.org/10.1021/acschembio.0c00357
Publikováno v:
Methods (San Diego, Calif.). 205
In the development of therapeutics, it is important to establish engagement of a compound to its intended target and identify other targets it binds to. Methods for demonstrating target engagement in the growing field of RNA-targeted therapeutics are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2afdb180a82820efaa8373eccace26e
https://pubmed.ncbi.nlm.nih.gov/35764246
https://pubmed.ncbi.nlm.nih.gov/35764246
Autor:
Paula Stein, Nikolay V Rozhkov, Fan Li, Fabián L Cárdenas, Olga Davydenko, Lee E Vandivier, Brian D Gregory, Gregory J Hannon, Richard M Schultz
Publikováno v:
PLoS Genetics, Vol 11, Iss 2, p e1005013 (2015)
The RNase III enzyme DICER generates both microRNAs (miRNAs) and endogenous short interfering RNAs (endo-siRNAs). Both small RNA species silence gene expression post-transcriptionally in association with the ARGONAUTE (AGO) family of proteins. In mam
Externí odkaz:
https://doaj.org/article/36cad606f7e245a3902daf17f4a773ca
Autor:
Andrew D. L. Nelson, Marianne C. Kramer, Kevin A. Janssen, Kyle Palos, Eric Lyons, Benjamin A. Garcia, Brian D. Gregory, Lee E. Vandivier, Mark A. Beilstein
Publikováno v:
Plant Direct, Vol 4, Iss 7, Pp n/a-n/a (2020)
Plant Direct
Plant Direct
After transcription, a messenger RNA (mRNA) is further post‐transcriptionally regulated by several features including RNA secondary structure and covalent RNA modifications (specifically N6‐methyladenosine, m6A). Both RNA secondary structure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d16ca35ce7d88b339ebac2c0cdea36
https://doaj.org/article/80905837322145e8b608b1550305e467
https://doaj.org/article/80905837322145e8b608b1550305e467
Autor:
Xiang, Yu, Matthew R, Willmann, Lee E, Vandivier, Sophie, Trefely, Marianne C, Kramer, Jeffrey, Shapiro, Rong, Guo, Eric, Lyons, Nathaniel W, Snyder, Brian D, Gregory
Publikováno v:
Dev Cell
Although eukaryotic messenger RNAs (mRNAs) normally possess a 5’ end N(7)-methyl guanosine (m(7)G) cap, a non-canonical 5’ nicotinamide adenine dinucleotide (NAD(+)) cap can tag certain transcripts for degradation mediated by the NAD(+) decapping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::813ca689f48b55f87e9c875d29ead00e
https://pubmed.ncbi.nlm.nih.gov/33290723
https://pubmed.ncbi.nlm.nih.gov/33290723
Autor:
Gregory L Peterfreund, Lee E Vandivier, Rohini Sinha, Andre J Marozsan, William C Olson, Jun Zhu, Frederic D Bushman
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46966 (2012)
Antibiotic disruption of the intestinal microbiota may cause susceptibility to pathogens that is resolved by progressive bacterial outgrowth and colonization. Succession is central to ecological theory but not widely documented in studies of the vert
Externí odkaz:
https://doaj.org/article/633eafe0460a4fdeac4da4441b058c68
Autor:
Lee E. Vandivier, Brian D. Gregory
Publikováno v:
Journal of Experimental Botany. 69:4659-4665
Throughout all kingdoms of life, ribonucleotides are marked with covalent chemical modifications that change the structure and binding properties of modified RNA molecules. These marks are deposited by 'writer' proteins, recognized by 'readers', and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6c8e293c067a98f5db5bead127d1ab
https://doi.org/10.1093/jxb/ery262
https://doi.org/10.1093/jxb/ery262
Autor:
Atul Kakrana, Parth Patel, Sandra M. Mathioni, Lee E. Vandivier, Bruce Kingham, Kun Huang, Olga Shevchenko, Jim Leebens-Mack, Reza Hammond, Blake C. Meyers, Siwaret Arikit, Brian D. Gregory, Alex Harkess
Publikováno v:
Genome Research. 28:1333-1344
In grasses, two pathways that generate diverse and numerous 21-nt (premeiotic) and 24-nt (meiotic) phased siRNAs are highly enriched in anthers, the male reproductive organs. These “phasiRNAs” are analogous to mammalian piRNAs, yet their function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac15fd5b94c67f81a952a4cefdd9d181
https://doi.org/10.1101/gr.228163.117
https://doi.org/10.1101/gr.228163.117