Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Lee Davies"'
Autor:
Thomas Williams-Fegredo, Lee Davies, Carol Knevelman, Kyriacos Mitrophanous, James Miskin, Qasim A. Rafiq
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Both cell surface and soluble extracellular glycosaminoglycans have been shown to interfere with the exogenous nucleic acid delivery efficiency of non-viral gene delivery, including lipoplex and polyplex-mediated transfection. Most gene therapy viral
Externí odkaz:
https://doaj.org/article/30f18ce1f17f438ab64d69f10643272c
Autor:
Thomas Williams-Fegredo, Lee Davies, Carol Knevelman, Kyriacos Mitrophanous, James Miskin, Qasim A. Rafiq
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101260- (2024)
Large-scale transient transfection has advanced significantly over the last 20 years, enabling the effective production of a diverse range of biopharmaceutical products, including viral vectors. However, a number of challenges specifically related to
Externí odkaz:
https://doaj.org/article/3197910bb8934f0bb12e559c15fef757
Autor:
Thomas Williams, Kevin Kalinka, Rui Sanches, Greg Blanchard-Emmerson, Samuel Watts, Lee Davies, Carol Knevelman, Laura McCloskey, Peter Jones, Kyriacos Mitrophanous, James Miskin, Duygu Dikicioglu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Process analytical technology (PAT) has demonstrated huge potential to enable the development of improved biopharmaceutical manufacturing processes by ensuring the reliable provision of quality products. However, the complexities associated
Externí odkaz:
https://doaj.org/article/5ba382014cbb4084ad4e23ec8b56f489
Autor:
Tiziana Ulian, Mauricio Diazgranados, Samuel Pironon, Stefano Padulosi, Udayangani Liu, Lee Davies, Melanie‐Jayne R. Howes, James S. Borrell, Ian Ondo, Oscar A. Pérez‐Escobar, Suzanne Sharrock, Philippa Ryan, Danny Hunter, Mark A. Lee, Charles Barstow, Łukasz Łuczaj, Andrea Pieroni, Rodrigo Cámara‐Leret, Arshiya Noorani, Chikelu Mba, Rémi Nono Womdim, Hafiz Muminjanov, Alexandre Antonelli, Hugh W. Pritchard, Efisio Mattana
Publikováno v:
Plants, People, Planet, Vol 2, Iss 5, Pp 421-445 (2020)
Societal Impact Statement Biodiversity is essential to food security and nutrition locally and globally. By reviewing the global state of edible plants and highlighting key neglected and underutilized species (NUS), we attempt to unlock plant food re
Externí odkaz:
https://doaj.org/article/162534353ff74e7aa6ce55ca0272ab57
Autor:
Tony Le Gall, Mathieu Berchel, Lee Davies, Angélique Mottais, Rosy Ghanem, Alain Fautrel, Deborah Gill, Steve Hyde, Pierre Lehn, Jean-Marie Lehn, Loïc Lemiègre, Thierry Benvegnu, Paul-Alain Jaffrès, Bruno Pitard, Tristan Montier
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 25 (2021)
Aerosol lung gene therapy using non-viral delivery systems represents a credible therapeutic strategy for chronic respiratory diseases, such as cystic fibrosis (CF). Progress in CF clinical setting using the lipidic formulation GL67A has demonstrated
Externí odkaz:
https://doaj.org/article/3ac96a9742de4b9ca532dc89bdc93c79
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239388 (2020)
BackgroundPoor knowledge concerning appropriate antibiotic use significantly influences the misuse of antibiotics within the community, especially in developing countries where there are weaker health systems to regulate antibiotic dispensing. Antibi
Externí odkaz:
https://doaj.org/article/f12e95aa8bea4dc6ab657bd2a9dc2315
Autor:
Sarah C. Gilbert, Scott Bruce, Daniel C. Smith, Sarah Davies, Carina Citra Dewi Joe, Adam Berg, Adam J. Ritchie, Daniel Pappas, Yuanyuan Li, Piergiuseppe Nestola, Maria Kapanidou, Amar Joshi, Paul Cashen, Gaurav Gupta, Raghavan Venkat, Alexander D. Douglas, Lee Davies, David O. Mainwaring, Mark Woodyer, Richard Turner, Daan Bormans, Jonathan Humphreys, Sofiya Fedosyuk, Catherine M. Green, Nick Smith, Dennis Verbart, Nitin Chopra, Nicole Bleckwenn, Teresa Lambe, Jinlin Jiang, Rameswara R Segireddy, Thomas Linke, Lisa Cooper, Byron Rees, Carol Knevelman
Publikováno v:
Biotechnology and Bioengineering
Manufacturing has been the key factor limiting rollout of vaccination during the COVID‐19 pandemic, requiring rapid development and large‐scale implementation of novel manufacturing technologies. ChAdOx1 nCoV‐19 (AZD1222, Vaxzevria) is an effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78020b799701a9645d14a6b2ea46dd38
https://ora.ox.ac.uk/objects/uuid:9aab02ba-dac8-40f5-979a-f773c0fbf98d
https://ora.ox.ac.uk/objects/uuid:9aab02ba-dac8-40f5-979a-f773c0fbf98d
Autor:
Oscar Alejandro Pérez-Escobar, Mauricio Diazgranados, Ian Ondo, Rémi Nono Womdim, Philippa Ryan, Udayangani Liu, Łukasz Łuczaj, Alexandre Antonelli, Charles Barstow, Rodrigo Cámara-Leret, James S. Borrell, Lee Davies, Chikelu, Efisio Mattana, Suzanne Sharrock, Arshiya Noorani, Hafiz Muminjanov, Hugh W. Pritchard, Melanie-Jayne R. Howes, Andrea Pieroni, Stefano Padulosi, Danny Hunter, Samuel Pironon, Tiziana Ulian, Mark A. Lee
Publikováno v:
Plants, People, Planet, Vol 2, Iss 5, Pp 421-445 (2020)
Societal Impact Statement Biodiversity is essential to food security and nutrition locally and globally. By reviewing the global state of edible plants and highlighting key neglected and underutilized species (NUS), we attempt to unlock plant food re
Autor:
Oliver Goodyear, Carol Knevelman, James Miskin, Michael Bransby, Thomas Williams, Lee Davies, Kyriacos Mitrophanous
Publikováno v:
Cell and Gene Therapy Insights. 6:455-467
Autor:
Mariann Eilertsen, Wayne Iwan Lee Davies, Dharmeshkumar Patel, Jonathan E. Barnes, Rita Karlsen, Jessica Kate Mountford, Deborah L. Stenkamp, Jagdish Suresh Patel, Jon Vidar Helvik
Publikováno v:
Frontiers in Neuroanatomy
Salmonids are ideal models as many species follow a distinct developmental program from demersal eggs and a large yolk sac to hatching at an advanced developmental stage. Further, these economically important teleosts inhabit both marine- and freshwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6aa17f7635b2f25dc5ba57d0075fb5
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-198333
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-198333