Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lee D, Ellis"'
Autor:
Michael G. Morash, Jessica Nixon, Lori M. N. Shimoda, Helen Turner, Alexander J. Stokes, Andrea L. Small-Howard, Lee D. Ellis
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Medicinal cannabis has shown promise for the symptomatic treatment of Parkinson’s disease (PD), but patient exposure to whole plant mixtures may be undesirable due to concerns around safety, consistency, regulatory issues, and psychoactivity. Ident
Externí odkaz:
https://doaj.org/article/4209c1573dbf455f9fcc70830700ff22
Autor:
Ananda Baskaran Venkatachalam, Bailey Levesque, John C. Achenbach, Jane J. Pappas, Lee D. Ellis
Publikováno v:
Toxics, Vol 11, Iss 2, p 151 (2023)
Selective serotonin reuptake inhibitors (SSRIs) are currently the most prescribed class of psychotropic medications. Their increased global manufacture and use have become growing concerns for aquatic toxicologists and environmental biologists, who a
Externí odkaz:
https://doaj.org/article/e526225023ac4a998b9775e65c76c8ed
Publikováno v:
Toxicological Sciences. 190:133-145
Zebrafish larvae have classically been used as a high-throughput model with which to test both the bioactivity and toxicity of known and novel compounds, making them a promising whole organism New Approach Method in the context of the international m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8891c862a2ce466153ccf2be69a558d4
https://doi.org/10.1093/toxsci/kfac102
https://doi.org/10.1093/toxsci/kfac102
Autor:
Andrea Tomko, Lauren O’Leary, Hilary Trask, John C. Achenbach, Steven R. Hall, Kerry B. Goralski, Lee D. Ellis, Denis J. Dupré
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Cannabinoids exhibit anti-inflammatory and antitumorigenic properties. Contrary to most cannabinoids present in the Cannabis plant, some, such as O-1602 and abnormal cannabidiol, have no or only little affinity to the CB1 or CB2 cannabinoid receptors
Externí odkaz:
https://doaj.org/article/6372d1fc7a684f0192e74b54ba440360
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
In this study, we aimed to investigate the effect of the two main active cannabinoids extracted from cannabis: Δ-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on two distinct behavioral models of induced neuro-hyperactivity. We have taken advan
Externí odkaz:
https://doaj.org/article/5b17baa7964246db8bcd3c31115b8139
Publikováno v:
Toxics, Vol 8, Iss 4, p 126 (2020)
The movement away from mammalian testing of potential toxicants and new chemical entities has primarily led to cell line testing and protein-based assays. However, these assays may not yet be sufficient to properly characterize the toxic potential of
Externí odkaz:
https://doaj.org/article/cd7aa085e4f641eea0aa656f6f43ec6c
Autor:
Ashley Cabecinha, Camilo F Martinez-Farina, Lee D. Ellis, Jessica Nixon, Joseph P. M. Hui, Hanan Abramovici
Publikováno v:
Journal of Cannabis Research
Journal of Cannabis Research, Vol 3, Iss 1, Pp 1-11 (2021)
Journal of Cannabis Research, Vol 3, Iss 1, Pp 1-11 (2021)
Background Whole-plant cannabis extracts are consumed by the public for medical and non-medical (“recreational”) purposes but are poorly researched compared to pure cannabinoids. There is emerging evidence that cannabis extracts comprising comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e36c4762f761a438b10f4a9b892a7f
https://doi.org/10.1186/s42238-021-00103-y
https://doi.org/10.1186/s42238-021-00103-y
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7985
Catechol is a ubiquitous chemical used in the manufacturing of fragrances, pharmaceuticals and flavorants. Environmental exposure occurs in a variety of ways through industrial processes, during pyrolysis and in effluent, yet despite its prevalence,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a28930dc60dda22029af8ef1a8eb351
https://doi.org/10.3390/ijms23147985
https://doi.org/10.3390/ijms23147985
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115305 (2014)
The smoking of tobacco continues to be the leading cause of premature death worldwide and is linked to the development of a number of serious illnesses including heart disease, respiratory diseases, stroke and cancer. Currently, cell line based toxic
Externí odkaz:
https://doaj.org/article/df3f1cd27a914cd49ca54213c676db0b
Autor:
Joseph P. M. Hui, John C. Achenbach, Lee D. Ellis, Arjun H. Banskota, Roumiana Stefanova, Fabrice Berrué
A new dihydrophenanthrene derivative namely 9,10-dihydro-5-hydroxy-2, 3,6-trimethoxyphenanthrene-1,4-dione (1) was isolated from commercial cannabis product together with 4,5-dihydroxy-2,3,6-trimethoxy-9,10-dihydrophenanthrene (2), 4-hydroxy-2,3,6,7-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6492a88574d8a3d2386f0f52ee658184
