Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lee Cheng Phua"'
Publikováno v:
BMC Health Services Research, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background The IMpassion130 trial demonstrated that adding atezolizumab to nanoparticle albumin-bound (nab)-paclitaxel improved the survival of patients with untreated, advanced, programmed death ligand 1 (PDL1)-positive triple-negative brea
Externí odkaz:
https://doaj.org/article/2ff44a98380b456aa1450fceb4a50bf9
Autor:
Kwong Ng, Fiona Pearce, Horace C.W. Choi, Cameron Hall, Mohamed Ismail Abdul Aziz, Lee Cheng Phua, Jeffrey Low, Joseph T. Wu, Mark Jit
Publikováno v:
Vaccine. 39:2255-2263
Background The nonavalent human papillomavirus (HPV) vaccine has been shown to extend protection against oncogenic HPV types 31/33/45/52/58 (HPV-OV) not covered by the bivalent and quadrivalent HPV vaccines. Besides its clinical benefit, evidence on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3285e868685474b62a018f829f45461e
https://doi.org/10.1016/j.vaccine.2021.03.040
https://doi.org/10.1016/j.vaccine.2021.03.040
Autor:
Syed Muhammad Fahmy Alkaff, Shixu Goh, Wei Qiang Leow, David Tai, Chung Yip Chan, Eric Chun Yong Chan, Tony Kiat Hon Lim, Juinn Huar Kam, Lee Cheng Phua
Publikováno v:
Cancer Chemotherapy and Pharmacology. 81:277-289
Resistance to gemcitabine remains a key challenge in the treatment of pancreatic ductal adenocarcinoma (PDAC), necessitating the constant search for effective strategies for a priori prediction of clinical outcome. While the existing studies focused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8b54022cfc6dcb217f2f10e8820537
https://doi.org/10.1007/s00280-017-3475-6
https://doi.org/10.1007/s00280-017-3475-6
Autor:
LEE CHENG PHUA1, HUI WEN NG1, HUI LING YEO, ANGIE1, CHEN, ELYA2, SHU MEI LO, MICHELLE2, PEH YEAN CHEAH2,3,4, CHUN YONG CHAN, ERIC1, POH KOON KOH2,5 kohpohkooncolorectal@gmail.com, HAN KIAT HO1 phahohk@nus.edu.sg
Publikováno v:
Oncology Letters. Oct2015, Vol. 10 Issue 4, p2519-2526. 8p.
Autor:
Elya Chen, Han Kiat Ho, Poh Koon Koh, Peh Yean Cheah, Angie Hui Ling Yeo, Eric Chun Yong Chan, Hui Wen Ng, Michelle Lo, Lee Cheng Phua
Publikováno v:
Oncology Letters. 10:2519-2526
Mutations in oncogenes along the epidermal growth factor receptor (EGFR) signaling pathway have been implicated in the resistance to cetuximab in patients with metastatic colorectal cancer (mCRC). However, the relative significance of these mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0faabeab2c21ad5d17823b09583eea
https://doi.org/10.3892/ol.2015.3560
https://doi.org/10.3892/ol.2015.3560
Autor:
Poh Koon Koh, Han Kiat Ho, Lee Cheng Phua, Xiu Ping Chue, Peh Yean Cheah, Eric Chun Yong Chan
Publikováno v:
Oncology Reports. 32:97-104
Fecal microRNAs (miRNAs) are increasingly explored as non-invasive markers of colorectal cancer (CRC). However, its holistic profile in Asian CRC patients remains elusive. In the present study, the global human fecal miRNAs in Asian Chinese CRC patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d4ccb82cb230e1ca62c9edef4a4478
https://doi.org/10.3892/or.2014.3193
https://doi.org/10.3892/or.2014.3193
Autor:
Edward R. Browne, Catherine W. Goh, Lee Sun New, Lee Cheng Phua, Eric Chun Yong Chan, Aveline H. Neo
Publikováno v:
Pharmaceutical Research. 25:2639-2649
To investigate the potential drug–drug interaction (DDI) between lipoic acid (LA) and valproate (VA) via the mitochondrial β-oxidation pathway in rats. In vitro mitochondrial assays were performed to compare the biotransformation of VA to valproyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53c0efc1c35a34cf544988f6dc01d8d
https://doi.org/10.1007/s11095-008-9681-5
https://doi.org/10.1007/s11095-008-9681-5
Autor:
Yee Min Tan, Lee Cheng Phua, Theebarina Gopalakrishnan, Ali Keshavarzian, Mary E. Kan, Jia Lu, Reuben K Wong, Clive H. Wilder-Smith, Xinhua Li, Eric Chun Yong Chan
Publikováno v:
Journal of proteome research. 14(11)
Physical and psychological stress have been shown to modulate multiple aspects of gastrointestinal (GI) physiology, but its molecular basis remains elusive. We therefore characterized the stress-induced metabolic phenotype (metabotype) in soldiers du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6497a9520a5805fde25622eea2d3104e
https://pubmed.ncbi.nlm.nih.gov/26506213
https://pubmed.ncbi.nlm.nih.gov/26506213
Autor:
Peh Yean Cheah, Han Kiat Ho, Xiu Ping Chue, Lee Cheng Phua, Eric Chun Yong Chan, Poh Koon Koh
Colorectal cancer (CRC) is a major cause of mortality in many developed countries. Effective screening strategies were called for to facilitate timely detection and to promote a better clinical outcome. In this study, the role of fecal metabonomics i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc2389ad5e90b84e7a8197d0b6c34f7
https://europepmc.org/articles/PMC3979816/
https://europepmc.org/articles/PMC3979816/
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 937
Gas chromatography mass spectrometry (GC/MS)-based fecal metabonomics represents a powerful systems biology approach for elucidating metabolic biomarkers of lower gastrointestinal tract (GIT) diseases. Unlike metabolic profiling of fecal water, the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e25bc9b262d9737fe6669d3b837b42
https://pubmed.ncbi.nlm.nih.gov/24029555
https://pubmed.ncbi.nlm.nih.gov/24029555