Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lee C. Speight"'
Autor:
Nathan W. G. Fairhurst, Rachel A. Harper, Holly K. Smith, Lee C. Speight, Joseph S. Clements II, Elizabeth R. Jenkinson
Publikováno v:
Engineering Biology (2019)
The manufacture of bio-chemicals through the use of microbial fermentation and renewable feedstock has a number of well-known advantages linked to sustainability and reduced impacts on the environment. Markets for molecules produced with greener cred
Externí odkaz:
https://doaj.org/article/59cf9ed55b124f3f8c8259103af565b4
Autor:
Carol Deutsch, Ya-Ming Hou, Pengse Po, Lee C. Speight, Howard Gamper, Andrey Kosolapov, D. Miklos Szantai-Kis, LiWei Tu, E. James Petersson, Erin Delaney
Publikováno v:
Journal of Molecular Biology. 429:1873-1888
All proteins are synthesized by the ribosome, a macromolecular complex that accomplishes the life-sustaining tasks of faithfully decoding mRNA and catalyzing peptide bond formation at the peptidyl transferase center (PTC). The ribosome has evolved an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c5b23b76a28436af4f608df37fcab0
https://doi.org/10.1016/j.jmb.2017.04.019
https://doi.org/10.1016/j.jmb.2017.04.019
Autor:
Lee C. Speight, Zachary M Hostetler, Camden M. Driggers, Jeffery G. Saven, Lea Z. Mbengi, Rahul M. Kohli, José A. Villegas, John J. Perona, Robert J. Blizzard, Itthipol Sungwienwong, E. James Petersson, Ryan A. Mehl, Joseph J. Porter
Publikováno v:
Organic & Biomolecular Chemistry. 15:3603-3610
The amino acid acridon-2-ylalanine (Acd) can be a valuable probe of protein dynamics, either alone or as part of a Förster resonance energy transfer (FRET) or photo-induced electron transfer (eT) probe pair. We have previously reported the genetic i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa81492101a864299bb76a8b05dfbaef
https://doi.org/10.1039/c7ob00582b
https://doi.org/10.1039/c7ob00582b
Autor:
Murugesh Padmanarayana, Colin P. Johnson, Lee C. Speight, Nicole Hams, Ryan A. Mehl, E. James Petersson
Publikováno v:
Biochemistry
Otoferlin is a transmembrane protein consisting of six C2 domains, proposed to act as a calcium sensor for exocytosis. Although otoferlin is believed to bind calcium and lipids, the lipid specificity and identity of the calcium binding domains are co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e617f9471b7e00ebbdc85ffc32aeea41
https://doi.org/10.1021/bi5004469
https://doi.org/10.1021/bi5004469
Autor:
Ryan A. Mehl, Lee C. Speight, Anand K. Muthusamy, Rebecca F. Wissner, Jacob M. Goldberg, Taylor S. Willi, John B. Warner, E. James Petersson, Bradley F. Woodman
Publikováno v:
Journal of the American Chemical Society. 135:18806-18814
The amino acid acridon-2-ylalanine (Acd) can be a valuable probe of protein conformational change because it is a long lifetime, visible wavelength fluorophore that is small enough to be incorporat...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eb0791e88377aa0dc3a7e21f71e610b
https://doi.org/10.1021/ja403247j
https://doi.org/10.1021/ja403247j
Publikováno v:
Journal of the American Chemical Society. 134(14)
Fluorescent probe pairs that can be selectively excited in the presence of Trp and Tyr are of great utility in studying conformational changes in proteins. However, the size of these probe pairs can restrict their incorporation to small portions of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c543010499302e1b7ee48ec399431be4
https://pubmed.ncbi.nlm.nih.gov/22471784
https://pubmed.ncbi.nlm.nih.gov/22471784
Autor:
Lee C. Speight, Robert J. Hinkle, Yajing Lian, Heather E. Stevenson, Melissa M. Sprachman, M. Christa Mattern, Lauren A. Katkish
Publikováno v:
Tetrahedron. 65(34)
The rapid synthesis of cis-2,6-disubstituted dihydropyrans is achieved in a three-component, one-pot cascade reaction. BiBr(3)-ediated addition of ketene silyl acetals or silyl enol ethers to beta,gamma-unsaturated cis-4-trimethylsilyl-3-butenal prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777d279f36bc857ace9550851de659b3
https://pubmed.ncbi.nlm.nih.gov/20161364
https://pubmed.ncbi.nlm.nih.gov/20161364
Autor:
Lee C. Speight, M. Christa Mattern, Melissa M. Sprachman, Lauren A. Katkish, Yajing Lian, Heather E. Stevenson, Robert J. Hinkle
Publikováno v:
ChemInform. 40
The rapid synthesis of cis-2,6-disubstituted dihydropyrans is achieved in a three-component, one-pot cascade reaction. BiBr(3)-ediated addition of ketene silyl acetals or silyl enol ethers to beta,gamma-unsaturated cis-4-trimethylsilyl-3-butenal prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e4a42b8f95416c9ffdda42f262db4f6
https://doi.org/10.1002/chin.200952155
https://doi.org/10.1002/chin.200952155
Publikováno v:
Australian Journal of Chemistry. 67:686
Fluorescence methods allow one to monitor protein conformational changes, protein–protein associations, and proteolysis in real time, at the single molecule level and in living cells. The information gained in such experiments is a function of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::132778e8317f0c57de753ec95f702ba3
https://doi.org/10.1071/ch13554
https://doi.org/10.1071/ch13554