Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lee B. Honig"'
Autor:
Liora S. Katz, Gabriel Brill, Pili Zhang, Anil Kumar, Sharon Baumel-Alterzon, Lee B. Honig, Nicolás Gómez-Banoy, Esra Karakose, Marius Tanase, Ludivine Doridot, Alexandra Alvarsson, Bennett Davenport, Peng Wang, Luca Lambertini, Sarah A. Stanley, Dirk Homann, Andrew F. Stewart, James C. Lo, Mark A. Herman, Adolfo Garcia-Ocaña, Donald K. Scott
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
ChREBP is a glucose-responsive transcription factor, which regulates glucose-mediated proliferation and cell death in pancreatic β-cells. Here the authors show that the acute feed forward induction of ChREBPβ is required for adaptive β-cell expans
Externí odkaz:
https://doaj.org/article/f2c908c5343543e98a1a127b3ec55963
Autor:
Liora S. Katz, Gabriel Brill, Pili Zhang, Anil Kumar, Sharon Baumel-Alterzon, Lee B. Honig, Nicolás Gómez-Banoy, Esra Karakose, Marius Tanase, Ludivine Doridot, Alexandra Alvarsson, Bennett Davenport, Peng Wang, Luca Lambertini, Sarah A. Stanley, Dirk Homann, Andrew F. Stewart, James C. Lo, Mark A. Herman, Adolfo Garcia-Ocaña, Donald K. Scott
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/de30955e01f54ed4b9fb1d77ba69bc7b
Autor:
Cole M. Haynes, Adolfo Garcia-Ocaña, Misung Kim, Dirk Homann, Bennett Davenport, Mark A. Herman, Liora S. Katz, Jerry E. Chipuk, Lucy Li, Anna M Schulz, Donald K. Scott, Lee B Honig, Anil Kumar
Publikováno v:
Diabetes
Patients with both major forms of diabetes would benefit from therapies that increase β-cell mass. Glucose, a natural mitogen, drives adaptive expansion of β-cell mass by promoting β-cell proliferation. We previously demonstrated that a carbohydra
Autor:
Mélanie Ethier, Liora S. Katz, Lee B Honig, Donald K. Scott, Mallikarjuna R. Metukuri, Vincent Poitout, Gabriel Brill, Julien Ghislain, Hasna Maachi, Grace Fergusson
Publikováno v:
Diabetes
The molecular mechanisms of β-cell compensation to metabolic stress are poorly understood. We previously observed that nutrient-induced β-cell proliferation in rats is dependent on Epidermal Growth Factor Receptor (EGFR) signaling. The aim of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7941aefe05cb3971db47282c6ab6fc95
https://doi.org/10.1101/683003
https://doi.org/10.1101/683003
Publikováno v:
American Journal of Food Science and Technology. 2:175-178
SCFA(Short Chain Fatty Acids) are readily absorbed in the gastrointestinal tract and play an important role in the maintenance of gut health. The deficiency of SCFA (particularly acetic, propionic and butyric) may affect the pathogenesis of a diverse