Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lee Anne McLean"'
Autor:
Charles E Geyer, Michael Untch, Aleix Prat, Priya Rastogi, Naoki Niikura, Elton Mathias, Lee Anne McLean, Yibin Wang, Sibylle Loibl
Publikováno v:
Cancer Research. 82:OT1-02
Background Preoperative chemotherapy in combination with trastuzumab and pertuzumab is a preferred regimen for treating patients (pts) with HER2-positive, invasive, early breast cancer (BC). Pts who have received such treatment but still have residua
Autor:
Sukrut Shah, Vladimir Kostorov, Lee Anne McLean, Takashi Kojima, Jong-Mu Sun, Ying Zhu, Manish A. Shah, Lin Shen, Mustafa Ozguroglu, Antoine Adenis, Toshihiko Doi, Peter C. Enzinger, Ken Kato, Byoung Chul Cho, Cinta Hierro, Jaafar Bennouna
Publikováno v:
Future Oncology. 15:1057-1066
MUSTAFA, OZGUROGLU/0000-0002-8417-8628 WOS:000468121800002 PubMed ID: 30735435 Background: Treatment options for patients with advanced esophageal or esophagogastric junction (EGJ) cancer are limited. Current guidelines for first-line treatment of ad
Autor:
Yibin Wang, Lee Anne McLean, Aleix Prat, Sibylle Loibl, Priya Rastogi, Naoki Niikura, Charles E. Geyer, Michael Untch, Elton Mathias
Publikováno v:
Cancer Research. 81:OT-03
Background Preoperative chemotherapy in combination with trastuzumab and pertuzumab is a preferred regimen for treating patients (pts) with HER2-positive, invasive, early breast cancer (BC). Pts who have received such treatment but still have residua
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 101:144-151
BACKGROUND Aliskiren is the first orally bioavailable direct renin inhibitor approved for the treatment of hypertension in adults. Juvenile toxicity studies in rats were initiated to support treatment in the pediatric population. METHODS In Study 1,
Autor:
Armin Wolf, Francois Pognan, Nandita Shangari, Lee Anne McLean, Elba Cruz, Parul Patel, Salah-Dine Chibout, Shruthi Sampath, Pierre Moulin, Steve Busch, Chiara Buono, Albert Reising, Maya Gurnani
Publikováno v:
Toxicological Sciences
Toxicological Sciences; Vol 126
Toxicological Sciences; Vol 126
Lens explant cultures were used to assess the mechanism of drug-induced cataractogenic potential of NVS001, a peroxisome proliferator-activated receptor delta (PPARδ) agonist, which resulted in cataract in all treated animals during a 13-week rat st
Autor:
Mihael H. Polymeropoulos, Lee Anne McLean, Renaud Capdeville, Rachel Helene Malinowski, Marlene A. Dressman, Martee L. Hensley, Insa Gathmann
Publikováno v:
Clinical Cancer Research. 10:2265-2271
Purpose: Imatinib, an inhibitor of the Bcr-Abl tyrosine kinase, is indicated for the treatment of patients with Philadelphia chromosome-positive chronic myeloid leukemia. We examined genotypes from patients enrolled in the International Randomized St
Autor:
Robert L. Hong, Lee Anne McLean, James K. Bubien, G. Yancey Gillespie, Catherine M. Fuller, Timothy B. Mapstone, Kailin Lee, Dale J. Benos, James M. Markert, Steven R. Gullans
Publikováno v:
Physiological Genomics. 5:21-33
Gene expression profiling of three human temporal lobe brain tissue samples (normal) and four primary glioblastoma multiforme (GBM) tumors using oligonucleotide microarrays was done. Moreover, confirmation of altered expression was performed by whole
Publikováno v:
Toxicology and applied pharmacology. 275(1)
Juvenile rat toxicity studies with the direct renin inhibitor aliskiren were initiated to support treatment in the pediatric population. In Study 1, aliskiren was administered orally to juvenile rats at doses of 0, 30, 100 or 300 mg/kg/day with repea
Publikováno v:
Birth defects research. Part B, Developmental and reproductive toxicology. 101(2)
Aliskiren is the first orally bioavailable direct renin inhibitor approved for the treatment of hypertension in adults. Juvenile toxicity studies in rats were initiated to support treatment in the pediatric population.In Study 1, aliskiren oral admin
Autor:
Lee Anne McLean, Marlene A. Dressman, Mihael H. Polymeropoulos, Renaud Capdeville, Insa Gathmann
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 10(1 Pt 1)
Purpose: To better understand the molecular basis of cytogenetic response in chronic myeloid leukemia patients treated with imatinib, we studied gene expression profiles from a total of 100 patients from a large, multinational Phase III clinical tria