Výsledky vyhledávání - "Lee Anne C. Boutilier"

An efficient helper-virus-free method for rescue of recombinant paramyxoviruses and rhadoviruses from a cell line suitable for vaccine development

Autor: J. Erik Johnson, Stephen A. Udem, R. Michael Hendry, Cheryl S. Kotash, Christopher L. Parks, Aaron S. Abramovitz, Krista J. Melville, Sannyu G. Heron, Susan E. Witko, Mohinder S. Sidhu, David K. Clarke, Rebecca M. Nowak, Lee Anne C. Boutilier

Publikováno v: Journal of Virological Methods. 135:91-101

Recovery of recombinant, negative-strand, nonsegmented RNA viruses from a genomic cDNA clone requires a rescue system that promotes de novo assembly of a functional ribonucleoprotein (RNP) complex in the cell cytoplasm. This is accomplished typically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c116e875bf05776830d61f2e47c2ee
https://doi.org/10.1016/j.jviromet.2006.02.006

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Alphavirus replicon particles encoding the fusion or attachment glycoproteins of respiratory syncytial virus elicit protective immune responses in BALB/c mice and functional serum antibodies in rhesus macaques

Autor: John H. Eldridge, Michael A. Egan, Nicole B. Terio, Krista J. Melville, Deborah Long, Amara Luckay, Lee Anne C. Boutilier, Christopher L. Parks, Rashed Abdullah, Stephen A. Udem, Robert A. Lerch, Matthew B. Elliott, Tong Chen, Siew-Yen Chong, Gerald E. Hancock

Publikováno v: Vaccine. 25(41)

Respiratory syncytial virus (RSV) is a major cause of acute respiratory tract disease in humans. Towards development of a prophylactic vaccine, we genetically engineered Venezuelan equine encephalitis virus (VEEV) replicons encoding the fusion (Fa) o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f11b66bf0fdcf90a01044f2fc2d93d
https://pubmed.ncbi.nlm.nih.gov/17850933

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Characterization of recombinant respiratory syncytial viruses with the region responsible for type 2 T-cell responses and pulmonary eosinophilia deleted from the attachment (G) protein

Autor: Robert A. Lerch, Natisha A. LaPierre, C. K. Gupta, Karin S. Pryharski, Matthew B. Elliott, Lee Anne C. Boutilier, Valerie B. Randolph, Kristen M. Heers Dack, Gerald E. Hancock, Krista J. Melville, Qingzhong Yu, Todd S. Laughlin, N. Campeol

Publikováno v: Journal of virology. 78(16)

It is essential that preventative vaccines for respiratory syncytial virus (RSV) elicit balanced T-cell responses. Immune responses dominated by type 2 T cells against RSV antigens are believed to cause exaggerated respiratory tract disease and may a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26244742bb8b23ecf31ca7bcc2778780
https://pubmed.ncbi.nlm.nih.gov/15280453

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