High Monocyte Count and Expression of

Autor: Anna-Maja, Åberg, Sofia Halin, Bergström, Elin, Thysell, Lee-Ann, Tjon-Kon-Fat, Jonas A, Nilsson, Anders, Widmark, Camilla, Thellenberg-Karlsson, Anders, Bergh, Pernilla, Wikström, Marie, Lundholm

Publikováno v: Cancers

Simple Summary Prostate tumors are heterogeneous with unpredictable outcomes, ranging from harmless to aggressive, metastatic and deadly disease. Current diagnostic methods have limited ability to predict disease aggressiveness. New biomarkers are ur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6ad329491e8beb196339472ec6f2132e
https://pubmed.ncbi.nlm.nih.gov/34067757

Real-Time Monitoring of Nuclear Factor κB Activity in Cultured Cells and in Animal Models

Autor: Christian E. Badr, Johanna M. Niers, Lee-Ann Tjon-Kon-Fat, David P. Noske, Thomas Wurdinger, Bakhos A. Tannous

Publikováno v: Molecular Imaging, Vol 8 (2009)

Nuclear factor κB (NF-κB) is a transcription factor that plays a major role in many human disorders, including immune diseases and cancer. We designed a reporter system based on NF-κB responsive promoter elements driving expression of the secreted

Externí odkaz: https://doaj.org/article/b40a1e096c794f3dac3ecf00eb1ce8f3

Platelets harbor prostate cancer biomarkers and the ability to predict therapeutic response to abiraterone in castration resistant patients

Autor: Marie Lundholm, Camilla Thellenberg-Karlsson, Thomas Wurdinger, Pernilla Wikström, Lee-Ann Tjon-Kon-Fat, Anders Widmark, Rolf Jonas Nilsson, Mona Schröder

Publikováno v: Prostate, 78(1), 48-53. Wiley-Liss Inc.
Tjon-Kon-Fat, L-A, Lundholm, M, Schröder, M, Wurdinger, T, Thellenberg-Karlsson, C, Widmark, A, Wikström, P & Nilsson, R J A 2018, ' Platelets harbor prostate cancer biomarkers and the ability to predict therapeutic response to abiraterone in castration resistant patients ', Prostate, vol. 78, no. 1, pp. 48-53 . https://doi.org/10.1002/pros.23443

Background: Novel therapies for castration resistant prostate cancer (CRPC) have been introduced in the clinic with possibilities for individualized treatment plans. Best practice of those expensive drugs requires predictive biomarker monitoring. Thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153c39abe2cb97f81c75ccb69f01e41f
https://research.vumc.nl/en/publications/567e6983-365a-432b-abaa-46c44a3ddea0

Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets

Autor: Anna E. Huis In ‘t Veld, Michel M van den Heuvel, Pieter Wesseling, Niki Karachaliou, Nik Sol, Aniko V. Fejes, Adrianus J. de Langen, Michal Heger, Pepijn Schellen, Laura L. Meijer, Jilian D. Schoonhoven, Hanne Meijers-Heijboer, Sjors G J G In 't Veld, Bakhos A. Tannous, Irsan E. Kooi, Jose Gomez-Arroyo, Jillian Bracht, Rafael Rosell, Anna Larissa N. Niemeijer, Joep Killestein, Mirte Muller, Michelle Esenkbrink, Egbert F. Smit, Imo E. Hoefer, Jihane Tannous, Elizabeth Lee-Lewandrowski, Geert Kazemier, Heleen Verschueren, Francesca Favaro, Sander Idema, Bauke Ylstra, François Rustenburg, Rolf T. Urbanus, W. Peter Vandertop, Laurine E. Wedekind, Christine Mannhalter, Harm Jan Bogaard, Cyra E. Leurs, Adrienne Vancura, Lee Ann Tjon Kon Fat, Edward Post, Leon J Wils, Myron G. Best, Saskia C.A. de Jager, R. Jonas A. Nilsson, Jaap C. Reijneveld, Gerard Pasterkamp, Tessa Y S Le Large, Kent B. Lewandrowski, Elisa Giovannetti, Daan van den Broek, David P. Noske, Thomas Wurdinger

Publikováno v: Cancer Cell, 32(2), 238-252.e9. Cell Press
Cancer Cell
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Cancer Cell, 32, 238-252.e9
Best, M G, Sol, N, In ‘t Veld, S G J G, Vancura, A, Muller, M, Niemeijer, A L N, Fejes, A V, Tjon Kon Fat, L A, Huis In ‘t Veld, A E, Leurs, C, Le Large, T Y, Meijer, L L, Kooi, I E, Rustenburg, F, Schellen, P, Verschueren, H, Post, E, Wedekind, L E, Bracht, J, Esenkbrink, M, Wils, L, Favaro, F, Schoonhoven, J D, Tannous, J, Meijers-Heijboer, H, Kazemier, G, Giovannetti, E, Reijneveld, J C, Idema, S, Killestein, J, Heger, M, de Jager, S C, Urbanus, R T, Hoefer, I E, Pasterkamp, G, Mannhalter, C, Gomez-Arroyo, J, Bogaard, H J, Noske, D P, Vandertop, W P, van den Broek, D, Ylstra, B, Nilsson, R J A, Wesseling, P, Karachaliou, N, Rosell, R, Lee-Lewandrowski, E, Lewandrowski, K B, Tannous, B A, de Langen, A J, Smit, E F, van den Heuvel, M M & Wurdinger, T 2017, ' Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets ', Cancer Cell, vol. 32, no. 2, pp. 238-252.e9 . https://doi.org/10.1016/j.ccell.2017.07.004
Cancer Cell, 32(2), 238. Cell Press
Cancer Cell, 32, 2, pp. 238-252.e9
Cancer cell, 32(2), 238-252.e9. Cell Press

Summary Blood-based liquid biopsies, including tumor-educated blood platelets (TEPs), have emerged as promising biomarker sources for non-invasive detection of cancer. Here we demonstrate that particle-swarm optimization (PSO)-enhanced algorithms ena

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b4b869f8ee10ef55699cd8a7901a32
https://doi.org/10.1016/j.ccell.2017.07.004

Abstract 3158: Prostate cancer derived biomarkers within platelets have the ability to predict therapeutic response in castration resistant patients

Autor: Lee-Ann Tjon-Kon-Fat, Thomas Wurdinger, Jonas Nilsson, Camilla Thellenberg-Karlsson, Marie Lundholm, Pernilla Wikström, Anders Widmark

Publikováno v: Cancer Research. 76:3158-3158

Background: Novel therapies for castration resistant prostate cancer (CRPC) have been introduced in the clinic with possibilities for individualized treatment plans. Best practice of those expensive drugs requires predictive biomarker monitoring. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ebd82257d4755b0c6ddbbab4376d631
https://doi.org/10.1158/1538-7445.am2016-3158