Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Lee Ann MacMillan‐Crow"'
Autor:
Keishla M. Rodríguez-Graciani, Xavier R. Chapa-Dubocq, Lee Ann MacMillan-Crow, Sabzali Javadov
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 6, Pp 1101-1114 (2020)
Externí odkaz:
https://doaj.org/article/b33d899e72fb4fed9ae82b5cc71694d8
Autor:
Andrew R. Kulek, Vishnu V. R. Undyala, Anthony R. Anzell, Sarita Raghunayakula, Lee Ann MacMillan-Crow, Thomas H. Sanderson, Karin Przyklenk
Publikováno v:
Cells, Vol 11, Iss 19, p 3083 (2022)
Disruption of mitochondrial structure/function is well-recognized to be a determinant of cell death in cardiomyocytes subjected to lethal episodes of ischemia-reperfusion (IR). However, the precise mitochondrial event(s) that precipitate lethal IR in
Externí odkaz:
https://doaj.org/article/5f7aee62b8e046d39d7c38a21688594a
Publikováno v:
Antioxidants, Vol 10, Iss 8, p 1272 (2021)
Kidneys from deceased donors undergo cold storage (CS) preservation before transplantation. Although CS is a clinical necessity for extending organ quality preservation, CS causes mitochondrial and renal injury. Specifically, many studies, including
Externí odkaz:
https://doaj.org/article/718d9ee7b67a4250af3cf17fc37f9bb2
Autor:
Nirmala Parajuli, Stephen Shrum, Julia Tobacyk, Alex Harb, John M Arthur, Lee Ann MacMillan-Crow
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185542 (2017)
The majority of transplanted kidneys are procured from deceased donors which all require exposure to cold storage (CS) for successful transplantation. Unfortunately, this CS leads to renal and mitochondrial damage but, specific mitochondrial targets
Externí odkaz:
https://doaj.org/article/841594e297274f0ea0dcf1074463c410
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 348-357 (2014)
Superoxide is widely regarded as the primary reactive oxygen species (ROS) which initiates downstream oxidative stress. Increased oxidative stress contributes, in part, to many disease conditions such as cancer, atherosclerosis, ischemia/reperfusion,
Externí odkaz:
https://doaj.org/article/0e4bc2f8f0ab4267a70ef9c7dce0cf29
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48590 (2012)
Cold preservation has greatly facilitated the use of cadaveric kidneys for transplantation but damage occurs during the preservation episode. It is well established that oxidant production increases during cold renal preservation and mitochondria are
Externí odkaz:
https://doaj.org/article/e80c95dcf5d04b038e0e8bd066d228ab
Autor:
Balamurugan Packialakshmi, Ian J. Stewart, David M. Burmeister, Xiaoming Zhou, Kevin K. Chung, Xiao C. Li, Manoocher Soleimani, Jia L. Zhuo, Lee Ann MacMillan‐Crow
Publikováno v:
The FASEB Journal. 36
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 3049
Cannabinoids exert anti-cancer actions; however, the underlying cytotoxic mechanisms and the cannabinoid receptors (CBRs) involved remain unclear. In this study, CBRs were characterized in several cancer cell lines. Radioligand binding screens surpri
Publikováno v:
Antioxidants, Vol 10, Iss 1272, p 1272 (2021)
Antioxidants
Volume 10
Issue 8
Antioxidants
Volume 10
Issue 8
Kidneys from deceased donors undergo cold storage (CS) preservation before transplantation. Although CS is a clinical necessity for extending organ quality preservation, CS causes mitochondrial and renal injury. Specifically, many studies, including
Publikováno v:
Mitochondrion
Mitochondria continually undergo fission and fusion which allow mitochondria to rapidly change their shape, size, and function throughout the cell life cycle. OMA1, a zinc metalloproteinase enzyme, is a key regulator of the mitochondrial fusion machi