Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Lee A. Shapiro"'
Autor:
Jaclyn Iannucci, Reagan Dominy, Shreya Bandopadhyay, E. Madison Arthur, Brenda Noarbe, Amandine Jullienne, Margret Krkasharyan, Richard P. Tobin, Aleksandr Pereverzev, Samantha Beevers, Lavanya Venkatasamy, Karienn A. Souza, Daniel C. Jupiter, Alan Dabney, Andre Obenaus, M. Karen Newell-Rogers, Lee A. Shapiro
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-24 (2024)
Abstract Background Traumatic brain injury (TBI) is a significant risk factor for Alzheimer’s disease (AD), and accumulating evidence supports a role for adaptive immune B and T cells in both TBI and AD pathogenesis. We previously identified B cell
Externí odkaz:
https://doaj.org/article/7fbfabe044294bf4bcec2f591179eada
Autor:
Fushun Wang, Wei Wang, Simeng Gu, Dan Qi, Nathan A. Smith, Weiguo Peng, Wei Dong, Jiajin Yuan, Binbin Zhao, Ying Mao, Peng Cao, Qing Richard Lu, Lee A. Shapiro, S. Stephen Yi, Erxi Wu, Jason H. Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Despite extensive research on astrocytic Ca2+ in synaptic transmission, its contribution to the modulation of sensory transmission during different brain states remains largely unknown. Here, by using two-photon microscopy and whole-cell rec
Externí odkaz:
https://doaj.org/article/64660405c12e4785a602c29e47963d5e
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16084 (2023)
Traumatic brain injury (TBI) is a major health concern. Each year, over 50 million individuals worldwide suffer from TBI, and this leads to a number of acute and chronic health issues. These include affective and cognitive impairment, as well as an i
Externí odkaz:
https://doaj.org/article/19fa202b3f1e42858d2523806933834f
Autor:
Sanjib Mukherjee, Gabriel M. Arisi, Kaley Mims, Gabriela Hollingsworth, Katherine O’Neil, Lee A. Shapiro
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background Traumatic brain injury (TBI) occurs in as many as 64–74 million people worldwide each year and often results in one or more post-traumatic syndromes, including depression, cognitive, emotional, and behavioral deficits. TBI can a
Externí odkaz:
https://doaj.org/article/731c9edd9d3f411bb03e195c744e39a5
Autor:
M. Karen Newell-Rogers, Amanda Duong, Rizwan Nazarali, Richard P. Tobin, Susannah K. Rogers, Lee A. Shapiro
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9851 (2022)
TBI induces splenic B and T cell expansion that contributes to neuroinflammation and neurodegeneration. The vagus nerve, the longest of the cranial nerves, is the predominant parasympathetic pathway allowing the central nervous system (CNS) control o
Externí odkaz:
https://doaj.org/article/a61b346caaf54e85bcbb078e8d58aaa0
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/50d2c7326ffc48698d779a68a35b5d84
Autor:
M. Karen Newell-Rogers, Susannah K. Rogers, Richard P. Tobin, Sanjib Mukherjee, Lee A. Shapiro
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7448 (2020)
Traumatic brain injury (TBI) precedes the onset of epilepsy in up to 15–20% of symptomatic epilepsies and up to 5% of all epilepsy. Treatment of acquired epilepsies, including post-traumatic epilepsy (PTE), presents clinical challenges, including f
Externí odkaz:
https://doaj.org/article/9f765ab149ec4ed79e067e70539f1047
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 276 (2019)
Neuroinflammation is implicated in a host of neurological insults, such as traumatic brain injury (TBI), ischemic stroke, Alzheimer’s disease, Parkinson’s disease, and epilepsy. The immune response to central nervous system (CNS) injury involves
Externí odkaz:
https://doaj.org/article/17362082d3e74c85be6a9f262749fccf
Publikováno v:
Neural Plasticity, Vol 2018 (2018)
Externí odkaz:
https://doaj.org/article/46a2498183ec403293767085f60a4bea
Autor:
Lee A. Shapiro
Publikováno v:
Cell Transplantation, Vol 26 (2017)
Traumatic brain injury (TBI) is a devastating disorder causing negative outcomes in millions of people each year. Despite the alarming number of brain injuries and the long-term detrimental outcomes that can be associated with TBI, treatment options
Externí odkaz:
https://doaj.org/article/32b4a0a8571040cf9c58f6e0bc505d4f