Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Lee A. Davies"'
Autor:
Lee A. Davies, Graciela A. Nunez-Alonso, Henry L. Hebel, Ron K. Scheule, Seng H. Cheng, Stephen C. Hyde, Deborah R. Gill
Publikováno v:
BioTechniques, Vol 49, Iss 3, Pp 666-668 (2010)
Nonviral gene therapy utilizing plasmid DNA (pDNA) complexed with cationic lipids (lipoplexes) or cationic polymers (polyplexes) has demonstrated considerable potential for the treatment of a variety of diseases. However, progress toward clinical app
Externí odkaz:
https://doaj.org/article/3e046d23ba124e4cbd0b7377bfd128a7
Publikováno v:
Corporate Governance: The international journal of business in society, 2009, Vol. 9, Issue 1, pp. 50-57.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/14720700910936056
Autor:
Eric WFW Alton, David K Armstrong, Deborah Ashby, Katie J Bayfield, Diana Bilton, Emily V Bloomfield, A Christopher Boyd, June Brand, Ruaridh Buchan, Roberto Calcedo, Paula Carvelli, Mario Chan, Seng H Cheng, David S Collie, Steve Cunningham, Heather E Davidson, Gwyneth Davies, Jane C Davies, Lee A Davies, Maria H Dewar, Ann Doherty, Jackie Donovan, Natalie S Dwyer, Hala I Elgmati, Rosanna F Featherstone, Jemyr Gavino, Sabrina Gea-Sorli, Duncan M Geddes, James SR Gibson, Deborah R Gill, Andrew P Greening, Uta Griesenbach, David M Hansell, Katharine Harman, Tracy E Higgins, Samantha L Hodges, Stephen C Hyde, Laura Hyndman, J Alastair Innes, Joseph Jacob, Nancy Jones, Brian F Keogh, Maria P Limberis, Paul Lloyd-Evans, Alan W Maclean, Michelle C Manvell, Dominique McCormick, Michael McGovern, Gerry McLachlan, Cuixiang Meng, M Angeles Montero, Hazel Milligan, Laura J Moyce, Gordon D Murray, Andrew G Nicholson, Tina Osadolor, Javier Parra-Leiton, David J Porteous, Ian A Pringle, Emma K Punch, Kamila M Pytel, Alexandra L Quittner, Gina Rivellini, Clare J Saunders, Ronald K Scheule, Sarah Sheard, Nicholas J Simmonds, Keith Smith, Stephen N Smith, Najwa Soussi, Samia Soussi, Emma J Spearing, Barbara J Stevenson, Stephanie G Sumner-Jones, Minna Turkkila, Rosa P Ureta, Michael D Waller, Marguerite Y Wasowicz, James M Wilson, Paul Wolstenholme-Hogg, on behalf of the UK Cystic Fibrosis Gene Therapy Consortium
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 3, Iss 5 (2016)
Background: Cystic fibrosis (CF) is a chronic, life-limiting disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene leading to abnormal airway surface ion transport, chronic lung infections, inflammation and eventual re
Externí odkaz:
https://doaj.org/article/09b29fe1b155492fba24a177fe4be24c
Publikováno v:
Business Strategy Series, 2007, Vol. 8, Issue 4, pp. 246-253.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/17515630710684295
Publikováno v:
Leadership & Organization Development Journal, 2007, Vol. 28, Issue 3, pp. 196-208.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/01437730710739639
Publikováno v:
Handbook of Business Strategy, 2005, Vol. 6, Issue 1, pp. 177-184.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/08944310510557206
Autor:
Kenneth L Clark, Stephen A Hughes, Pallav Bulsara, Jill Coates, Kitty Moores, Joel Parry, Michael Carr, Ruth J Mayer, Paul Wilson, Chris Gruenloh, Daren Levin, Jill Darton, Wolf-Michael Weber, Katja Sobczak, Deborah R Gill, Stephen C Hyde, Lee A Davies, Ian A Pringle, Stephanie G Sumner-Jones, Vasant Jadhav, Sharon Jamison, Walter R Strapps, Victoria Pickering, Mark R Edbrooke
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Lung pathology in cystic fibrosis is linked to dehydration of the airways epithelial surface which in part results from inappropriately raised sodium reabsorption through the epithelial sodium channel (ENaC). To identify a small-interfering RNA (siRN
Externí odkaz:
https://doaj.org/article/b78fb7e93ba44314a82b90606a64ce1b
Autor:
Stephen C. Hyde, Tiong Kit Tan, Ian A. Pringle, Alain Townsend, Pramila Rijal, Deborah R. Gill, Lee A. Davies
Influenza A is a major global health threat causing >500,000 deaths annually. Neither prior infections nor current vaccines provide lasting protection, mainly due to rapid antigenic evolution of the viral haemagglutinin (HA) protein. Broadly neutrali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0710a0d9d7a5e00ac8e84b08d4a3ec0
https://doi.org/10.1016/s1525-0016(16)33240-3
https://doi.org/10.1016/s1525-0016(16)33240-3
Autor:
M M Connolly, Stephen C. Hyde, Stephanie G. Sumner-Jones, Ian A. Pringle, Martin Schleef, Lee A. Davies, Deborah R. Gill, Reto P. Bazzani
Publikováno v:
Biomaterials. 93:20-26
Non-viral aerosol gene therapy offers great potential for treating chronic lung diseases of the airways such as cystic fibrosis (CF). Early clinical trials showed that transgene expression in the airways was transient whereas maximal duration of tran
Autor:
Kamila M Pytel, Jean-François Gélinas, Deborah R. Gill, Lee A. Davies, Amit C. Nathwani, Stephen C. Hyde, Lidia Cammack, Makoto Inoue, Ian A. Pringle, Caroline Moran, Eric W.F.W. Alton, S Tsugumine, Michael C. Paul-Smith, Mario Chan, Takashi Hironaka, Loren Cameron, Cuixiang Meng, Uta Griesenbach, Jenny McIntosh, Robyn V. Bell
Publikováno v:
Gene Therapy
We have shown that a lentiviral vector (rSIV.F/HN) pseudotyped with the F and HN proteins from Sendai virus generates high levels of intracellular proteins after lung transduction. Here, we evaluate the use of rSIV.F/HN for production of secreted pro