Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Lee A, Gethings"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Omics-based biomarker technologies, including metabolic profiling (metabolomics/metabonomics) and lipidomics, are making a significant impact on disease understanding, drug development, and translational research. A wide range of patho-physi
Externí odkaz:
https://doaj.org/article/db8c1beb69784b7fbae96cf2910f2b92
Autor:
Johanna von Gerichten, Kyle Saunders, Melanie J. Bailey, Lee A. Gethings, Anthony Onoja, Nophar Geifman, Matt Spick
Publikováno v:
Metabolites, Vol 14, Iss 8, p 461 (2024)
Identification of features with high levels of confidence in liquid chromatography–mass spectrometry (LC–MS) lipidomics research is an essential part of biomarker discovery, but existing software platforms can give inconsistent results, even from
Externí odkaz:
https://doaj.org/article/f69f122041d04a2091a6a3e4389abb2e
Autor:
Tobias Kipura, Madlen Hotze, Alexa Hofer, Anna-Sophia Egger, Lea E. Timpen, Christiane A. Opitz, Paul A. Townsend, Lee A. Gethings, Kathrin Thedieck, Marcel Kwiatkowski
Publikováno v:
Metabolites, Vol 14, Iss 7, p 370 (2024)
Amino acids (AAs) and their metabolites are important building blocks, energy sources, and signaling molecules associated with various pathological phenotypes. The quantification of AA and tryptophan (TRP) metabolites in human serum and plasma is the
Externí odkaz:
https://doaj.org/article/55e625f04d3e46ea98d9e34b3d578d82
Autor:
Matt Spick, Ammara Muazzam, Hardev Pandha, Agnieszka Michael, Lee A. Gethings, Christopher J. Hughes, Nyasha Munjoma, Robert S. Plumb, Ian D. Wilson, Anthony D. Whetton, Paul A. Townsend, Nophar Geifman
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22604- (2023)
There is an unmet need for improved diagnostic testing and risk prediction for cases of prostate cancer (PCa) to improve care and reduce overtreatment of indolent disease. Here we have analysed the serum proteome and lipidome of 262 study participant
Externí odkaz:
https://doaj.org/article/f576a26c6dd04c70a60f53285740763e
Autor:
Bart Van Puyvelde, Simon Daled, Sander Willems, Ralf Gabriels, Anne Gonzalez de Peredo, Karima Chaoui, Emmanuelle Mouton-Barbosa, David Bouyssié, Kurt Boonen, Christopher J. Hughes, Lee A. Gethings, Yasset Perez-Riverol, Nic Bloomfield, Stephen Tate, Odile Schiltz, Lennart Martens, Dieter Deforce, Maarten Dhaenens
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-12 (2022)
Measurement(s) Digital Data Repository Technology Type(s) Digital Data Repository
Externí odkaz:
https://doaj.org/article/f0a8db72f31a46abb715ed17518c0a07
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Robust biological markers of dietary exposure are essential in improving the understanding of the link between diet and health outcomes. Polyphenolic compounds, including flavonoids, have been proposed to mitigate the risk of chronic disease
Externí odkaz:
https://doaj.org/article/8006c4dc784947648bcb93b26fdbeb8b
Publikováno v:
Metabolites, Vol 13, Iss 3, p 360 (2023)
There has been increasing interest in bacterial lipids in recent years due, in part, to their emerging role as molecular signalling molecules. Bacteroides thetaiotaomicron is an important member of the mammalian gut microbiota that has been shown to
Externí odkaz:
https://doaj.org/article/2dd7c7b1b3c944eb95cac180ed728a55
Autor:
Kenny Man, Mathieu Y. Brunet, Maria Fernandez‐Rhodes, Soraya Williams, Liam M. Heaney, Lee A. Gethings, Angelica Federici, Owen G. Davies, David Hoey, Sophie C. Cox
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 9, Pp n/a-n/a (2021)
Abstract Extracellular vesicles (EVs) are emerging in tissue engineering as promising acellular tools, circumventing many of the limitations associated with cell‐based therapies. Epigenetic regulation through histone deacetylase (HDAC) inhibition h
Externí odkaz:
https://doaj.org/article/b2f00d250dec44fa837f5f9ae6c149c1
Autor:
Matthew E. Daly, Kai Wang, Xiaoyan Pan, Rosa L. Depau, Justin Marsh, Francesco Capozzi, Phil Johnson, Lee A. Gethings, E. N. Clare Mills
Publikováno v:
Foods, Vol 11, Iss 14, p 2000 (2022)
Understanding how food processing may modify allergen bioaccessibility and the evolution of immunologically active peptides in the gastrointestinal tract is essential if knowledge-based approaches to reducing the allergenicity of food are to be reali
Externí odkaz:
https://doaj.org/article/8095405b14e14a208909996a2b91ff6f
Autor:
Matthew Daly, Sophie N. Bromilow, Chiara Nitride, Peter R. Shewry, Lee A. Gethings, E. N. Clare Mills
Publikováno v:
Frontiers in Nutrition, Vol 7 (2020)
Wheat gluten, and related prolamin proteins in rye, barley and oats cause the immune-mediated gluten intolerance syndrome, coeliac disease. Foods labelled as gluten-free which can be safely consumed by coeliac patients, must not contain gluten above
Externí odkaz:
https://doaj.org/article/14537fa886584c00af4501ec95e5678c