Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lee‐Jae Guo"'
Autor:
Sarah M. Schneider, Garett T. Sansom, Lee-Jae Guo, Shinji Furuya, Brad R. Weeks, Joe N. Kornegay
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2022)
BackgroundDuchenne muscular dystrophy (DMD) is an X-linked inherited myopathy that causes progressive skeletal and cardiac muscle disease. Heart lesions were described in the earliest DMD reports, and cardiomyopathy is now the leading cause of death.
Externí odkaz:
https://doaj.org/article/0393d9035c4542b9bd4bde72b9d9dd62
Autor:
Paul T Martin, Deborah A Zygmunt, Anna Ashbrook, Sonia Hamilton, Davin Packer, Sharla M Birch, Amanda K Bettis, Cynthia J Balog-Alvarez, Lee-Jae Guo, Peter P Nghiem, Joe N Kornegay
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248721 (2021)
We have examined the effects of intravenous (IV) delivery of rAAVrh74.MHCK7.GALGT2 in the golden retriever muscular dystrophy (GRMD) model of Duchenne Muscular Dystrophy (DMD). After baseline testing, GRMD dogs were treated at 3 months of age and rea
Externí odkaz:
https://doaj.org/article/8daea8ae30e441fc877a6ae566d3dfd6
Autor:
Lee‐Jae Guo, Jonathan H. Soslow, Amanda K. Bettis, Peter P. Nghiem, Kevin J. Cummings, Mark W. Lenox, Matthew W. Miller, Joe N. Kornegay, Christopher F. Spurney
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 16 (2019)
Background Duchenne muscular dystrophy (DMD) is an X‐linked disease that causes progressive muscle weakness. Affected boys typically die from respiratory or cardiac failure. Golden retriever muscular dystrophy (GRMD) is genetically homologous with
Externí odkaz:
https://doaj.org/article/21520871b58b4c7c9d2cda64abd81fc7
Autor:
Lee-Jae Guo, 郭立傑
96
Duplex Doppler ultrasonography is a valuable diagnostic tool in clinical medicine. Resistive index (RI), pulsatility index (PI), and systolic-to-diastolic flow velocities ratio (S/D ratio) are indirect measurements of blood flow resistance th
Duplex Doppler ultrasonography is a valuable diagnostic tool in clinical medicine. Resistive index (RI), pulsatility index (PI), and systolic-to-diastolic flow velocities ratio (S/D ratio) are indirect measurements of blood flow resistance th
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/40045503108364869142
Autor:
Sharla M. Birch, Michael W. Lawlor, Thomas J. Conlon, Lee-Jae Guo, Julie M. Crudele, Eleanor C. Hawkins, Peter P. Nghiem, Mihye Ahn, Hui Meng, Margaret J. Beatka, Brittany A. Fickau, Juan C. Prieto, Martin A. Styner, Michael J. Struharik, Courtney Shanks, Kristy J. Brown, Diane Golebiowski, Amanda K. Bettis, Cynthia J. Balog-Alvarez, Nathalie Clement, Kirsten E. Coleman, Manuela Corti, Xiufang Pan, Stephen D. Hauschka, J. Patrick Gonzalez, Carl A. Morris, Joel S. Schneider, Dongsheng Duan, Jeffrey S. Chamberlain, Barry J. Byrne, Joe. N. Kornegay
Publikováno v:
Science translational medicine. 15(677)
Duchenne muscular dystrophy (DMD) is a progressive muscle wasting disease caused by the absence of dystrophin, a membrane-stabilizing protein encoded by the DMD gene. Although mouse models of DMD provide insight into the potential of a corrective the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286334212cdab7cd1ec6f09084ab2d3f
https://pubmed.ncbi.nlm.nih.gov/36599002
https://pubmed.ncbi.nlm.nih.gov/36599002
Autor:
Sara Mata López, Amanda R Leal, Alexis M Rutledge, Peter P. Nghiem, Laney E Lord, Lee-Jae Guo, John Deramus, Alan Russell
Publikováno v:
Annals of Physical and Rehabilitation Medicine. 65:101611
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb0d4fdb001331d1fda9d8883e1f879
https://doi.org/10.1016/j.rehab.2021.101611
https://doi.org/10.1016/j.rehab.2021.101611
Autor:
Joe N. Kornegay, Christopher F. Spurney, Lee-Jae Guo, Jonathan H. Soslow, Peter P. Nghiem, Amanda K. Bettis
Publikováno v:
Circulation. 142
Introduction: Duchenne muscular dystrophy (DMD) and the genetically homologous model, golden retriever muscular dystrophy (GRMD), are x-linked conditions that cause progressive muscle wasting and cardiomyopathy. We previously defined a late onset DMD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f23e85ff21820da36c688a3f72d06138
https://doi.org/10.1161/circ.142.suppl_3.17108
https://doi.org/10.1161/circ.142.suppl_3.17108
Autor:
Mark Lenox, Kevin J. Cummings, Peter P. Nghiem, Jonathan H. Soslow, Christopher F. Spurney, Lee-Jae Guo, Matthew W. Miller, Amanda K. Bettis, Joe N. Kornegay
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Duchenne muscular dystrophy ( DMD ) is an X‐linked disease that causes progressive muscle weakness. Affected boys typically die from respiratory or cardiac failure. Golden retriever muscular dystrophy ( GRMD ) is genetically homologous w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8228205e0ab32c1bb6bc89ae138329
http://europepmc.org/articles/PMC6759898
http://europepmc.org/articles/PMC6759898
Autor:
Scott Jaques, Vidya Sridhar, Sarah Schneider, Stanislav Vitha, Heather Heath-Barnett, Amanda K. Bettis, Cynthia J. Balog-Alvarez, Alan C. Glowcwski, Lee-Jae Guo, Peter P. Nghiem, Joe N. Kornegay, Rachel Johnson
Publikováno v:
Molecular Imaging and Biology
Purpose Metabolic dysfunction in Duchenne muscular dystrophy (DMD) is characterized by reduced glycolytic and oxidative enzymes, decreased and abnormal mitochondria, decreased ATP, and increased oxidative stress. We analyzed glucose metabolism as a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0097e003b191b7c04886c6b80e3bb4f6
https://pubmed.ncbi.nlm.nih.gov/29508262
https://pubmed.ncbi.nlm.nih.gov/29508262
Autor:
Lee-Jae Guo, Amanda E. Coleman, Bruce W. Keene, Joe N. Kornegay, Sandra P. Tou, Sarah Schneider
Publikováno v:
Neuromuscular disorders : NMD. 26(6)
Golden retriever muscular dystrophy (GRMD) is a model for the genetically homologous human disease, Duchenne muscular dystrophy (DMD). Unlike the mildly affected mdx mouse, GRMD recapitulates the severe DMD phenotype. In addition to skeletal muscle i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef08cf37577bf237df52ef9814517344
https://pubmed.ncbi.nlm.nih.gov/27105608
https://pubmed.ncbi.nlm.nih.gov/27105608