Classification models for identifying skin sensitizers using in vitro alternatives to animal testing

Autor: Lee, Serom

Allergic contact dermatitis (ACD) is an inflammatory disease that occurs when chemicals known as sensitizers come in contact with the skin. Recent European legislation prohibits animal based screens of cosmetic ingredients. Current alternatives to an

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In vitro methods for screening transdermal formulations.

Autor: Tsai PC; Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers - The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA.; The Center for Dermal Research, New Jersey Center for Biomaterials, Rutgers - The State University of New Jersey, 145 Bevier Rd, Piscataway, NJ 08854, USA., Lee S; Department of Biomedical Engineering, Rutgers - The State University of New Jersey, 599 Taylor Road, Piscataway, NJ 08854, USA., Michniak-Kohn B; Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers - The State University of New Jersey, 160 Frelinghuysen Road, Piscataway, NJ 08854, USA.; The Center for Dermal Research, New Jersey Center for Biomaterials, Rutgers - The State University of New Jersey, 145 Bevier Rd, Piscataway, NJ 08854, USA.

Publikováno v: Therapeutic delivery [Ther Deliv] 2015; Vol. 6 (9), pp. 1043-52. Date of Electronic Publication: 2015 Sep 30.