Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lee, Marcus CS"'
Autor:
Armstrong, Jane F, Campo, Brice, Alexander, Stephen PH, Arendse, Lauren B, Cheng, Xiu, Davenport, Anthony P, Faccenda, Elena, Fidock, David A, Godinez-Macias, Karla P, Harding, Simon D, Kato, Nobutaka, Lee, Marcus CS, Luth, Madeline R, Mazitschek, Ralph, Mittal, Nimisha, Niles, Jacquin C, Okombo, John, Ottilie, Sabine, Pasaje, Charisse Flerida A, Probst, Alexandra S, Rawat, Mukul, Rocamora, Frances, Sakata-Kato, Tomoyo, Southan, Christopher, Spedding, Michael, Tye, Mark A, Yang, Tuo, Zhao, Na, Davies, Jamie A
Antimalarial drug discovery has until recently been driven by high-throughput phenotypic cellular screening, allowing millions of compounds to be assayed and delivering clinical drug candidates. In this review, we will focus on target-based approache
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::4d380130dac8fd2fb970369c12f8763e
https://www.repository.cam.ac.uk/handle/1810/350816
https://www.repository.cam.ac.uk/handle/1810/350816
Autor:
Armstrong, Jane, Campo, Brice, Alexander, Stephen P H, Arendse, Lauren B, Cheng, Xiu, Davenport, Anthony P, Faccenda, Elena, Fidock, David A, Godinez-Macias, Karla P, Harding, Simon D, Kato, Nobutaka, Lee, Marcus CS, Luth, Madeline R, Mazitschek, Ralph, Mittal, Nimisha, Niles, Jacquin C, Okombo, John, Ottilie, Sabine, Pasaje, Charisse Flerida A, Probst, Alexandra S, Rawat, Mikul, Rocamora, Frances, Sakata-Kato, Tomoyo, Southan, Christopher, Spedding, Michael, Tye, Mark A, Yang, Tuo, Zhao, Na, Davies, Jamie A
Publikováno v:
Armstrong, J, Campo, B, Alexander, S P H, Arendse, L B, Cheng, X, Davenport, A P, Faccenda, E, Fidock, D A, Godinez-Macias, K P, Harding, S D, Kato, N, Lee, M CS, Luth, M R, Mazitschek, R, Mittal, N, Niles, J C, Okombo, J, Ottilie, S, Pasaje, C F A, Probst, A S, Rawat, M, Rocamora, F, Sakata-Kato, T, Southan, C, Spedding, M, Tye, M A, Yang, T, Zhao, N & Davies, J A 2023, ' Advances in Malaria Pharmacology and the online Guide to MALARIA PHARMACOLOGY : IUPHAR review 38 ', British Journal of Pharmacology, vol. 180, no. 15, pp. 1899-1929 . https://doi.org/10.1111/bph.16144
Antimalarial drug discovery has until recently been driven by high-throughput phenotypic cellular screening, allowing millions of compounds to be assayed and delivering clinical drug candidates. In this review, we will focus on target-based approache
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::c6bbe9df822ebed40bf906a8529a3082
https://www.pure.ed.ac.uk/ws/files/363876435/British_J_Pharmacology_2023_Armstrong_Advances_in_malaria_pharmacology_and_the_online_guide_to_MALARIA_PHARMACOLOGY_.pdf
https://www.pure.ed.ac.uk/ws/files/363876435/British_J_Pharmacology_2023_Armstrong_Advances_in_malaria_pharmacology_and_the_online_guide_to_MALARIA_PHARMACOLOGY_.pdf
Autor:
Armstrong, Jane F, Campo, Brice, Alexander, Stephen PH, Arendse, Lauren B, Cheng, Xiu, Davenport, Anthony P, Faccenda, Elena, Fidock, David A, Godinez-Macias, Karla P, Harding, Simon D, Kato, Nobutaka, Lee, Marcus CS, Luth, Madeline R, Mazitschek, Ralph, Mittal, Nimisha, Niles, Jacquin C, Okombo, John, Ottilie, Sabine, Pasaje, Charisse Flerida A, Probst, Alexandra S, Rawat, Mukul, Rocamora, Frances, Sakata-Kato, Tomoyo, Southan, Christopher, Spedding, Michael, Tye, Mark A, Yang, Tuo, Zhao, Na, Davies, Jamie A
Antimalarial drug discovery has until recently been driven by high-throughput phenotypic cellular screening, allowing millions of compounds to be assayed and delivering clinical drug candidates. In this review, we will focus on target-based approache
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0cf51aafb72c5e96478c9c66d234134
https://www.repository.cam.ac.uk/handle/1810/350119
https://www.repository.cam.ac.uk/handle/1810/350119
Autor:
Hoshizaki, Johanna, Adjalley, Sophie H, Thathy, Vandana, Judge, Kim, Berriman, Matthew, Reid, Adam J, Lee, Marcus CS
Acknowledgements: We thank Chris Newbold for his role in supporting the generation of the short-read sequencing. We thank Emma Betteridge, Alexander Dove and Sanger Scientific Operations for their assistance in generating the long-read RNA sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82614352692bf5221b547bc9d51ae279
Autor:
Baragaña, Beatriz, Hallyburton, Irene, Lee, Marcus CS, Norcross, Neil R, Grimaldi, Raffaella, Otto, Thomas D, Proto, William R, Blagborough, Andrew M, Meister, Stephan, Wirjanata, Grennady, Ruecker, Andrea, Upton, Leanna M, Abraham, Tara S, Almeida, Mariana J, Pradhan, Anupam, Porzelle, Achim, Luksch, Torsten, Martínez, María Santos, Bolscher, Judith M, Woodland, Andrew, Norval, Suzanne, Zuccotto, Fabio, Thomas, John, Simeons, Frederick, Stojanovski, Laste, Osuna-Cabello, Maria, Brock, Paddy M, Churcher, Tom S, Sala, Katarzyna A, Zakutansky, Sara E, Jiménez-Díaz, María Belén, Sanz, Laura Maria, Riley, Jennifer, Basak, Rajshekhar, Campbell, Michael, Avery, Vicky M, Sauerwein, Robert W, Dechering, Koen J, Noviyanti, Rintis, Campo, Brice, Frearson, Julie A, Angulo-Barturen, Iñigo, Ferrer-Bazaga, Santiago, Gamo, Francisco Javier, Wyatt, Paul G, Leroy, Didier, Siegl, Peter, Delves, Michael J, Kyle, Dennis E, Wittlin, Sergio, Marfurt, Jutta, Price, Ric N, Sinden, Robert E, Winzeler, Elizabeth A, Charman, Susan A, Bebrevska, Lidiya, Gray, David W, Campbell, Simon, Fairlamb, Alan H, Willis, Paul A, Rayner, Julian C, Fidock, David A, Read, Kevin D, Gilbert, Ian H
Publikováno v:
Nature, vol 522, iss 7556
There is an urgent need for new drugs to treat malaria, with broad therapeutic potential and novel modes of action, to widen the scope of treatment and to overcome emerging drug resistance. Here we describe the discovery of DDD107498, a compound with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::9ae0e7acbcdadc88d5abe0bbdf2135ad
https://escholarship.org/uc/item/1m64023f
https://escholarship.org/uc/item/1m64023f
Autor:
Karpiyevich, Maryia, Adjalley, Sophie, Mol, Marco, Ascher, David, Mason, Bethany, Van Der Heden Van Noort, Gerbrand, Laman, Heike, Ovaa, Huib, Lee, Marcus CS, Artavanis-Tsakonas, Katerina
Plasmodium parasites are the causative agents of malaria, a disease with wide public health repercussions. Increasing drug resistance and the absence of a vaccine make finding new chemotherapeutic strategies imperative. Components of the ubiquitin an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59e38571f95f66764645256a61ee42f2
Autor:
Carrasquilla, Manuela, Adjalley, Sophie, Sanderson, Theo, Marin-Menendez, Alejandro, Coyle, Rachael, Montandon, Ruddy, Rayner, Julian C, Pance, Alena, Lee, Marcus CS
The recurrent emergence of drug resistance in Plasmodium falciparum increases the urgency to genetically validate drug resistance mechanisms and identify new targets. Reverse genetics have facilitated genome-scale knockout screens in Plasmodium bergh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52a193df17036bdf18fbf54179b1ebb8
Autor:
Artavanis-Tsakonas, Katerina, Karpiyevich, Maryia, Adjalley, Sophie, Mol, Marco, Ascher, David, Mason, Bethany, Van Der Heden Van Noort, Gerbrand, Laman, Heike, Ovaa, Huib, Lee, Marcus CS
Plasmodium parasites are the causative agents of malaria, a disease with wide public health repercussions. Increasing drug resistance and the absence of a vaccine make finding new chemotherapeutic strategies imperative. Components of the ubiquitin an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b07c2c8683e12a473fa779e66856714
Autor:
Karpiyevich, Maryia, Adjalley, Sophie, Mol, Marco, Ascher, David B, Mason, Bethany, Van Der Heden Van Noort, Gerbrand, Laman, Heike, Ovaa, Huib, Lee, Marcus CS, Artavanis-Tsakonas, Katerina
Plasmodium parasites are the causative agents of malaria, a disease with wide public health repercussions. Increasing drug resistance and the absence of a vaccine make finding new chemotherapeutic strategies imperative. Components of the ubiquitin an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d7a524022400a2cd448d08f1f766ff6
Autor:
Lee MC; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032 USA., Fidock DA; Department of Microbiology and Immunology, Columbia University College of Physicians and Surgeons, New York, NY 10032 USA ; Division of Infectious Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032 USA.
Publikováno v:
Genome medicine [Genome Med] 2014 Aug 26; Vol. 6 (8), pp. 63. Date of Electronic Publication: 2014 Aug 26 (Print Publication: 2014).
