Individual functions of the histone acetyl transferases CBP and p300 in regulating the inflammatory response of synovial fibroblasts

Autor: Malgorzata Maciukiewicz, Marcel Gabathuler, Gideon Isaac Lee, Caroline Ospelt, Miriam Marks, Matija Tomšič, Monika Krošel, Larissa Moser, Katja Klein, Oliver Distler

Publikováno v: Krošel, Monika; Gabathuler, Marcel; Maciukiewicz, Malgorzata; Moser, Larissa; Lee, Gideon Isaac; Marks, Miriam; Tomšič, Matija; Distler, Oliver; Ospelt, Caroline; Klein, Kerstin (2021). Individual functions of the histone acetyl transferases CBP and p300 in regulating the inflammatory response of synovial fibroblasts. Journal of autoimmunity, 123, p. 102709. Elsevier 10.1016/j.jaut.2021.102709

Chromatin remodeling, and a persistent histone 3 lysine 27 acetylation (H3K27ac) in particular, are associated with a sustained inflammatory response of synovial fibroblasts (SF) in rheumatoid arthritis (RA). Here we investigated individual functions

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https://pubmed.ncbi.nlm.nih.gov/34304080