Genetic mechanisms governing sporulation initiation in Clostridioides difficile

Autor: Lee, Cheyenne D, Rizvi, Arshad, Edwards, Adrianne N, DiCandia, Michael A, Vargas Cuebas, Germán G, Monteiro, Marcos P, McBride, Shonna M

Publikováno v: In Current Opinion in Microbiology April 2022 66:32-38

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Glycine fermentation by C. difficile promotes virulence and spore formation, and is induced by host cathelicidin.

Autor: Rizvi A; Department of Microbiology and Immunology, Emory University School of Medicine, Emory Antibiotic Resistance Center , Atlanta, Georgia, USA., Vargas-Cuebas G; Department of Microbiology and Immunology, Emory University School of Medicine, Emory Antibiotic Resistance Center , Atlanta, Georgia, USA., Edwards AN; Department of Microbiology and Immunology, Emory University School of Medicine, Emory Antibiotic Resistance Center , Atlanta, Georgia, USA., DiCandia MA; Department of Microbiology and Immunology, Emory University School of Medicine, Emory Antibiotic Resistance Center , Atlanta, Georgia, USA., Carter ZA; Department of Microbiology and Immunology, Emory University School of Medicine, Emory Antibiotic Resistance Center , Atlanta, Georgia, USA., Lee CD; Department of Microbiology and Immunology, Emory University School of Medicine, Emory Antibiotic Resistance Center , Atlanta, Georgia, USA., Monteiro MP; Department of Microbiology and Immunology, Emory University School of Medicine, Emory Antibiotic Resistance Center , Atlanta, Georgia, USA., McBride SM; Department of Microbiology and Immunology, Emory University School of Medicine, Emory Antibiotic Resistance Center , Atlanta, Georgia, USA.

Publikováno v: Infection and immunity [Infect Immun] 2023 Oct 17; Vol. 91 (10), pp. e0031923. Date of Electronic Publication: 2023 Sep 27.