Výsledky vyhledávání - "Lee, Chao Zong"

Dissertation/ Thesis

Characterization of the active site of Escherichia coli methionine aminopeptidase by site - directed mutagenesis

Autor: Lee, Chao Zong, 李昭蓉

83
Methionine aminopeptidase (MAP) is a cobalt-dependent metalloenzyme which specifically cleaves the initial methionine from nascently synthesized proteins. MAP has been studied in pro karyotes and eukaryotes, but the structural and functional

Externí odkaz: http://ndltd.ncl.edu.tw/handle/29707743101817002546

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Wild-type FUS corrects ALS-like disease induced by cytoplasmic mutant FUS through autoregulation

Autor: Sanjuan-Ruiz, Inmaculada, Govea-Perez, Noé, Mcalonis-Downes, Melissa, Dieterle, Stéphane, Megat, Salim, Dirrig-Grosch, Sylvie, Picchiarelli, Gina, Piol, Diana, Zhu, Qiang, Myers, Brian, Lee, Chao-Zong, Cleveland, Don, Lagier-Tourenne, Clotilde, da Cruz, Sandrine, Dupuis, Luc

Publikováno v: Molecular Neurodegeneration
Molecular Neurodegeneration, BioMed Central, 2021, 16 (1), pp.61. ⟨10.1186/s13024-021-00477-w⟩
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-14 (2021)
Molecular Neurodegeneration, 2021, 16 (1), pp.61. ⟨10.1186/s13024-021-00477-w⟩

Mutations in FUS, an RNA-binding protein involved in multiple steps of RNA metabolism, are associated with the most severe forms of amyotrophic lateral sclerosis (ALS). Accumulation of cytoplasmic FUS is likely to be a major culprit in the toxicity o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::be28404c1db1f965f6058231e8bd2aa8
http://europepmc.org/articles/PMC8419956

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