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Abstract Toxic protein aggregates can spread among neurons to promote human neurodegenerative disease pathology. We found that in C. elegans touch neurons intermediate filament proteins IFD-1 and IFD-2 associate with aggresome-like organelles and are

Externí odkaz: https://doaj.org/article/7789921720d54283b486c645e8eba774

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Accurate and Interpretable Machine Learning for Transparent Pricing of Health Insurance Plans

Autor: Kshirsagar, Rohun, Hsu, Li-Yen, Chaturvedi, Vatshank, Greenberg, Charles H., McClelland, Matthew, Mohan, Anushadevi, Shende, Wideet, Tilmans, Nicolas P., Frigato, Renzo, Guo, Min, Chheda, Ankit, Trotter, Meredith, Ray, Shonket, Lee, Arnold, Alvarado, Miguel

Health insurance companies cover half of the United States population through commercial employer-sponsored health plans and pay 1.2 trillion US dollars every year to cover medical expenses for their members. The actuary and underwriter roles at a he

Externí odkaz: http://arxiv.org/abs/2009.10990

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Lee Arnold

Autor: Lee Arnold

Publikováno v: ACM SIGGRAPH 2005 Electronic Art and Animation Catalog.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7fc2a6c7ffcc8d4dc6b45c1c836a1813
https://doi.org/10.1145/1086057.1086070

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Akademický článek

Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell

Autor: Yu Wang, Meghan Lee Arnold, Anna Joelle Smart, Guoqiang Wang, Rebecca J Androwski, Andres Morera, Ken CQ Nguyen, Peter J Schweinsberg, Ge Bai, Jason Cooper, David H Hall, Monica Driscoll, Barth D Grant

Publikováno v: eLife, Vol 12 (2023)

Caenorhabditis elegans neurons under stress can produce giant vesicles, several microns in diameter, called exophers. Current models suggest that exophers are neuroprotective, providing a mechanism for stressed neurons to eject toxic protein aggregat

Externí odkaz: https://doaj.org/article/f03cd4354e174bee8cd967a06a26154e

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