Translating prognostic quantification of c-MYC and BCL2 from tissue microarrays to whole slide images in diffuse large B-cell lymphoma using deep learning

Autor: Thomas E. Tavolara, M. Khalid Khan Niazi, Andrew L. Feldman, David L. Jaye, Christopher Flowers, Lee A.D. Cooper, Metin N. Gurcan

Publikováno v: Diagnostic Pathology, Vol 19, Iss 1, Pp 1-13 (2024)

Abstract Background c-MYC and BCL2 positivity are important prognostic factors for diffuse large B-cell lymphoma. However, manual quantification is subject to significant intra- and inter-observer variability. We developed an automated method for qua

Externí odkaz: https://doaj.org/article/7c68eb8f1a58429a94ccbcc88f6fa070

Learning from crowds for automated histopathological image segmentation

Autor: López-Pérez, Miguel, Morales-Álvarez, Pablo, Cooper, Lee A.D., Felicelli, Christopher, Goldstein, Jeffery, Vadasz, Brian, Molina, Rafael, Katsaggelos, Aggelos K.

Publikováno v: In Computerized Medical Imaging and Graphics March 2024 112

Automated Deep Learning-Based Diagnosis and Molecular Characterization of Acute Myeloid Leukemia Using Flow Cytometry

Autor: Lewis, Joshua E., Cooper, Lee A.D., Jaye, David L., Pozdnyakova, Olga

Publikováno v: In Modern Pathology January 2024 37(1)

Machine learning classification of placental villous infarction, perivillous fibrin deposition, and intervillous thrombus

Autor: Goldstein, Jeffery A., Nateghi, Ramin, Irmakci, Ismail, Cooper, Lee A.D.

Publikováno v: In Placenta April 2023 135:43-50

Glioma progression is shaped by genetic evolution and microenvironment interactions

Autor: Varn, Frederick S., Johnson, Kevin C., Martinek, Jan, Huse, Jason T., Nasrallah, MacLean P., Wesseling, Pieter, Cooper, Lee A.D., Malta, Tathiane M., Wade, Taylor E., Sabedot, Thais S., Brat, Daniel, Gould, Peter V., Wöehrer, Adelheid, Aldape, Kenneth, Ismail, Azzam, Sivajothi, Santhosh K., Barthel, Floris P., Kim, Hoon, Kocakavuk, Emre, Ahmed, Nazia, White, Kieron, Datta, Indrani, Moon, Hyo-Eun, Pollock, Steven, Goldfarb, Christine, Lee, Ga-Hyun, Garofano, Luciano, Anderson, Kevin J., Nehar-Belaid, Djamel, Barnholtz-Sloan, Jill S., Bakas, Spyridon, Byrne, Annette T., D’Angelo, Fulvio, Gan, Hui K., Khasraw, Mustafa, Migliozzi, Simona, Ryan Ormond, D., Ha Paek, Sun, Van Meir, Erwin G., Walenkamp, Annemiek M.E., Watts, Colin, Weiss, Tobias, Weller, Michael, Alfaro, Kristin D., Amin, Samirkumar B., Ashley, David M., Bock, Christoph, Brodbelt, Andrew, Bulsara, Ketan R., Castro, Ana Valeria, Connelly, Jennifer M., Costello, Joseph F., de Groot, John F., Finocchiaro, Gaetano, French, Pim J., Golebiewska, Anna, Hau, Ann C., Hong, Chibo, Horbinski, Craig, Kannan, Kasthuri S., Kouwenhoven, Mathilde CM., Lasorella, Anna, LaViolette, Peter S., Ligon, Keith L., Lowman, Allison K., Mehta, Shwetal, Miletic, Hrvoje, Molinaro, Annette M., Ng, Ho Keung, Niclou, Simone P., Niers, Johanna M., Phillips, Joanna J., Rabadan, Raul, Rao, Ganesh, Reifenberger, Guido, Sanai, Nader, Short, Susan C., Sillevis Smitt, Peter, Sloan, Andrew E., Smits, Marion, Snyder, James M., Suzuki, Hiromichi, Tabatabai, Ghazaleh, Tanner, Georgette, Tomaszewski, William H., Wells, Michael, Westerman, Bart A., Wheeler, Helen, Xie, Jichun, Alfred Yung, W.K., Zadeh, Gelareh, Zhao, Junfei, Palucka, Karolina, Stead, Lucy F., Poisson, Laila M., Noushmehr, Houtan, Iavarone, Antonio, Verhaak, Roel GW., Ormond, D. Ryan, Paek, Sun Ha, Verhaak, Roel G.W.

Publikováno v: In Cell 9 June 2022 185(12):2184-2199