Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Leda Coelewij"'
Autor:
Alexandra E. Oppong, Leda Coelewij, Georgia Robertson, Lucia Martin-Gutierrez, Kirsty E. Waddington, Pierre Dönnes, Petra Nytrova, Rachel Farrell, Inés Pineda-Torra, Elizabeth C. Jury
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109225- (2024)
Summary: There are no blood-based biomarkers distinguishing patients with relapsing-remitting (RRMS) from secondary progressive multiple sclerosis (SPMS) although evidence supports metabolomic changes according to MS disease severity. Here machine le
Externí odkaz:
https://doaj.org/article/71777b4f62664398a66e0208bc11171f
Autor:
Chinar R. Parikh, Jaya K. Ponnampalam, George Seligmann, Leda Coelewij, Ines Pineda-Torra, Elizabeth C. Jury, Coziana Ciurtin
Publikováno v:
Therapeutic Advances in Musculoskeletal Disease, Vol 13 (2021)
The treatment of inflammatory arthritis has been revolutionised by the introduction of biologic treatments. Many biologic agents are currently licensed for use in both paediatric and adult patients with inflammatory arthritis and contribute to improv
Externí odkaz:
https://doaj.org/article/74660426bcef4a518370a981bdabc35a
Autor:
Kirsty E. Waddington, Artemis Papadaki, Leda Coelewij, Marsilio Adriani, Petra Nytrova, Eva Kubala Havrdova, Anna Fogdell-Hahn, Rachel Farrell, Pierre Dönnes, Inés Pineda-Torra, Elizabeth C. Jury
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background: Neutralizing anti-drug antibodies (ADA) can greatly reduce the efficacy of biopharmaceuticals used to treat patients with multiple sclerosis (MS). However, the biological factors pre-disposing an individual to develop ADA are poorly chara
Externí odkaz:
https://doaj.org/article/3f18697f0ea04704bfe363826743d56e
Autor:
Jaya Ponnampalam, George Seligmann, Ines Pineda-Torra, Chinar R. Parikh, Leda Coelewij, Coziana Ciurtin, Elizabeth C. Jury
Publikováno v:
Therapeutic Advances in Musculoskeletal Disease, Vol 13 (2021)
Therapeutic Advances in Musculoskeletal Disease
Therapeutic Advances in Musculoskeletal Disease
The treatment of inflammatory arthritis has been revolutionised by the introduction of biologic treatments. Many biologic agents are currently licensed for use in both paediatric and adult patients with inflammatory arthritis and contribute to improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c3f0d4a4608d8359ef27c711591bfa
https://doaj.org/article/74660426bcef4a518370a981bdabc35a
https://doaj.org/article/74660426bcef4a518370a981bdabc35a
Autor:
Andrew Nicolaides, Filipa Farinha, Ines Pineda-Torra, Edward J. Smith, Elvira Chocano, Kirsty E Waddington, Sara Croca, Leda Coelewij, Thomas McDonnell, Elizabeth C. Jury, Jyoti Bakshi, George Robinson, Maura Griffin, Pierre Dönnes, Anisur Rahman, Junjie Peng
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Patients with systemic lupus erythematosus (SLE) have an increased risk of developing cardiovascular disease. Standard serum lipid measurements in clinical practice do not predict cardiovascular disease risk in patients with SLE. More deta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee8bf26d3e158b38f42e2e543766912
https://pubmed.ncbi.nlm.nih.gov/33535791
https://pubmed.ncbi.nlm.nih.gov/33535791
Autor:
Yiannis Ioannou, Junjie Peng, Hannah Peckham, Coziana Ciurtin, Anna Radziszewska, Elizabeth C. Jury, Ines Pineda-Torra, George Robinson, Chris Wincup, Pierre Dönnes, Leda Coelewij, Meena Naja, David A. Isenberg
Publikováno v:
The Lancet Rheumatology
Summary Background Juvenile-onset systemic lupus erythematosus (SLE) is a rare autoimmune rheumatic disease characterised by more severe disease manifestations, earlier damage accrual, and higher mortality than in adult-onset SLE. We aimed to use mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfeb4c8709c340d345e6644356ffa290
https://pubmed.ncbi.nlm.nih.gov/32818204
https://pubmed.ncbi.nlm.nih.gov/32818204
Autor:
Elvira Chocano, Junjie Peng, Filipa Farinha, Andrew Nicolaides, Anisur Rahman, Kirsty E Waddington, Edward J. Smith, Ines Pineda-Torra, George Robinson, Thomas McDonnell, Sara Croca, Maura Griffin, Pierre Dönnes, Elizabeth C. Jury, Leda Coelewij
BackgroundPatients with systemic lupus erythematosus (SLE) have an increased risk of developing cardiovascular disease (CVD) and 30-40% have sub-clinical atherosclerosis on vascular ultrasound scanning. Standard measurements of serum lipids in clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96ba0b233b4899769f42c16bb1ce348
https://doi.org/10.1101/2020.08.11.20172536
https://doi.org/10.1101/2020.08.11.20172536
Autor:
George Robinson, Yiannis Ioannou, Coziana Ciurtin, Kirsty E Waddington, David A. Isenberg, Anna Radziszewska, Hannah Peckham, Ines Pineda-Torra, Chris Wincup, Leda Coelewij, Elizabeth C. Jury, Junjie Peng
Publikováno v:
Poster presentations.
Background Cardiovascular disease is the leading cause of mortality in patients with Juvenile-onset Systemic Lupus Erythematosus (JSLE) not attributable to lupus flare. This study used a multi-omic approach to investigate cardiovascular risk (CVR) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b752f53f4a020d8d4c395e356ae0ae56
https://doi.org/10.1136/lupus-2020-eurolupus.213
https://doi.org/10.1136/lupus-2020-eurolupus.213
Publikováno v:
Behavior Genetics
A previous study of exome-sequenced schizophrenia cases and controls reported an excess of singleton, gene-disruptive variants among cases, concentrated in particular gene sets. The dataset included a number of subjects with a substantial Finnish con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a07184c6e051808c060302dee59c0b
https://doi.org/10.1007/s10519-018-9893-3
https://doi.org/10.1007/s10519-018-9893-3
Autor:
Yiannis Ioannou, Ines Pineda-Torra, Chris Wincup, Pierre Dönnes, Anna Radziszewska, Leda Coelewij, Coziana Ciurtin, Elizabeth C. Jury, George Robinson, David A. Isenberg, Junjie Peng, Hannah Peckham
Juvenile-Onset systemic lupus erythematosus (JSLE) is an autoimmune rheumatic disease characterised by systemic inflammation and organ damage, with disease onset often coinciding with puberty. JSLE is associated with more severe disease manifestation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7eb680a20bb54a6ce496c8ca3964d48
https://doi.org/10.1101/19007765
https://doi.org/10.1101/19007765