Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Leda BASSIT"'
Autor:
Leda Bassit, Heather B. Bowers, Morgan Greenleaf, Courtney Sabino, Eric Lai, Grace Yu, Anne Piantadosi, Ethan Wang, William O’Sick, Kaleb McLendon, Julie A. Sullivan, Raymond F. Schinazi, Gregory L. Damhorst, Wilbur Lam, Anuradha Rao
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103146- (2024)
Summary: The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Alpha variant in 2020 demonstrated the need for reanalysis of diagnostic tests to ensure detection of emerging variants. Here, we present a protocol for creati
Externí odkaz:
https://doaj.org/article/6cb0f46685a94759850651855458f963
Autor:
Gregory L. Damhorst, Jessica Lin, Jennifer K. Frediani, Julie A. Sullivan, Adrianna Westbrook, Kaleb McLendon, Tyler J. Baugh, William H. O'Sick, John D. Roback, Anne L. Piantadosi, Jesse J. Waggoner, Leda Bassit, Anuradha Rao, Morgan Greenleaf, Jared W. O'Neal, Seegar Swanson, Nira R. Pollock, Greg S. Martin, Wilbur A. Lam, Joshua M. Levy
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27188- (2024)
Limited data highlight the need to understand differences in SARS-CoV-2 omicron (B.1.1.529) variant viral load between the gold standard nasopharyngeal (NP) swab, mid-turbinate (MT)/anterior nasal swabs, oropharyngeal (OP) swabs, and saliva. MT, OP,
Externí odkaz:
https://doaj.org/article/a7d65bc25cf743e9b31ba65d19e08f0d
Autor:
Emmanuel Merigeon, Dong Yang, Elizabeth Ihms, Leda Bassit, Elizabeth Fitzpatrick, Colleen Jonsson, Raymond Schinazi, David Block, Henrik Olsen
Publikováno v:
Pathogens and Immunity, Vol 7, Iss 1 (2022)
Background: The continued emergence of SARS-CoV-2 variants has caused concern that a constantly evolving virus will escape vaccines and antibody therapies. New approaches are needed. Methods: We created and manufactured an ACE2 extracellular domain
Externí odkaz:
https://doaj.org/article/fcc9b60707804cfbab69eb0d55de91c4
Autor:
Jennifer K. Frediani, Joshua M. Levy, Anuradha Rao, Leda Bassit, Janet Figueroa, Miriam B. Vos, Anna Wood, Robert Jerris, Van Leung-Pineda, Mark D. Gonzalez, Beverly B. Rogers, Maud Mavigner, Raymond F. Schinazi, Nils Schoof, Jesse J. Waggoner, Russell R. Kempker, Paulina A. Rebolledo, Jared W. O’Neal, Cheryl Stone, Ann Chahroudi, Claudia R. Morris, Allie Suessmith, Julie Sullivan, Sarah Farmer, Amanda Foster, John D. Roback, Thanuja Ramachandra, CaDeidre Washington, Kristie Le, Maria C. Cordero, Annette Esper, Eric J. Nehl, Yun F. Wang, Erika A. Tyburski, Greg S. Martin, Wilbur A. Lam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract While there has been significant progress in the development of rapid COVID-19 diagnostics, as the pandemic unfolds, new challenges have emerged, including whether these technologies can reliably detect the more infectious variants of concer
Externí odkaz:
https://doaj.org/article/30016094be9f470888a58161d2407fd5
Autor:
Eric Nehl, Stacy Heilman, David Ku, David Gottfried, Sarah Farmer, Robert Mannino, Erika Tyburski, Julie Sullivan, Allison Suessmith, Leda Bassit, Janet Figueroa, Anna Wood, Traci Leong, Anuradha Rao, Beverly Rogers, Robert Jerris, Sunita Park, Mark Gonzalez, Jennifer Frediani, Claudia Morris, Joshua Levy, Nils Schoof, Maud Mavigner, John Roback, Kristen Herzegh, Natia Saakadze, Jess Ingersoll, Narayana Cheedarla, Andrew Neish, Bradley Hanberry, Christopher Porter, Annette Esper, Russell Kempker, Paulina Rebolledo, Pamela McGuinness, Frederick Balagadde, Rebecca Gore, Ainat Koren, Nira Pollock, Eugene Rogers, Karl Simin, Nathaniel Hafer, Mary Ann Picard, Chiara Ghezzi, David McManus, Bryan Buchholz, Christina Rostad, Viviana Claveria, Thanuja Ramachandra, Yun F. Wang, CaDeidre Washington, Cheryl Stone, Mark Griffiths, Ray Schinazi, Ann Chahroudi, Miriam Vos, Oliver Brand, Greg Martin, Wilbur Lam
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 2, Pp 142-151 (2021)
Faced with the COVID-19 pandemic, the US system for developing and testing technologies was challenged in unparalleled ways. This article describes the multi-institutional, transdisciplinary team of the “RADxSM Tech Test Verification Core” and it
Externí odkaz:
https://doaj.org/article/97dd1f4fe14142b5900fb67b6edd4cb6
Autor:
Richard Creager, John Blackwood, Thomas Pribyl, Leda Bassit, Anuradha Rao, Morgan Greenleaf, Filipp Frank, Wilbur Lam, Eric Ortlund, Raymond Schinazi, Alexander Greninger, Mia Cirrincione, Dale Gort, Emily Kennedy, Adam Samuta, Megan Shaw, Brian Walsh, Eric Lai
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 2, Pp 286-290 (2021)
Goal: Monitoring the genetic diversity and emerging mutations of SARS-CoV-2 is crucial for understanding the evolution of the virus and assuring the performance of diagnostic tests, vaccines, and therapies against COVID-19. SARS-CoV-2 is still adapti
Externí odkaz:
https://doaj.org/article/02ba3987acda41658b1292e501fb96ab
Autor:
Anuradha Rao, Leda Bassit, Jessica Lin, Kiran Verma, Heather B. Bowers, Kimberly Pachura, Morgan Greenleaf, Julie Sullivan, Eric Lai, Richard S. Creager, Thomas Pribyl, John Blackwood, Anne L. Piantadosi, Raymond Schinazi, Greg S. Martin, Wilbur A. Lam
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103968- (2022)
Summary: As the emergence of SARS-CoV-2 variants brings the global pandemic to new levels, the performance of current rapid antigen tests against variants of concern and interest (VOC/I) is of significant public health concern. Here, we report assess
Externí odkaz:
https://doaj.org/article/acaf683acb5d412396d48a6ce2af977b
Autor:
Dharmeshkumar Patel, Suzane K. Ono, Leda Bassit, Kiran Verma, Franck Amblard, Raymond F. Schinazi
Publikováno v:
Molecules, Vol 27, Iss 17, p 5413 (2022)
Viral resistance is a worldwide problem mitigating the effectiveness of antiviral drugs. Mutations in the drug-targeting proteins are the primary mechanism for the emergence of drug resistance. It is essential to identify the drug resistance mutation
Externí odkaz:
https://doaj.org/article/d1e679fdc1854943b098379c587c31b7
Autor:
Sijia Tao, Keivan Zandi, Leda Bassit, Yee Tsuey Ong, Kiran Verma, Peng Liu, Jessica A. Downs-Bowen, Tamara McBrayer, Julia C. LeCher, James J. Kohler, Philip R. Tedbury, Baek Kim, Franck Amblard, Stefan G. Sarafianos, Raymond F. Schinazi
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 2, Iss , Pp 100045- (2021)
Remdesivir, a monophosphate prodrug of nucleoside analog GS-441524, is widely used for the treatment of moderate to severe COVID-19. It has been suggested to use GS-441524 instead of remdesivir in the clinic and in new inhalation formulations. Thus,
Externí odkaz:
https://doaj.org/article/d94330ccb3e0445a8d9165b90ad608da
Autor:
Keivan Zandi, Katie Musall, Adrian Oo, Dongdong Cao, Bo Liang, Pouya Hassandarvish, Shuiyun Lan, Ryan L. Slack, Karen A. Kirby, Leda Bassit, Franck Amblard, Baek Kim, Sazaly AbuBakar, Stefan G. Sarafianos, Raymond F. Schinazi
Publikováno v:
Microorganisms, Vol 9, Iss 5, p 893 (2021)
Coronavirus Disease 2019 (COVID-19) is a deadly emerging infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Because SARS-CoV-2 is easily transmitted through the air and has a relatively long incubation time, CO
Externí odkaz:
https://doaj.org/article/dbef7a9e52e146ea93a2afb9a5a52c12