Sialic acids on B cells are crucial for their survival and provide protection against apoptosis

Autor: Alexandra T. Linder, Michael Schmidt, Julia Hitschfel, Markus Abeln, Pascal Schneider, Rita Gerardy-Schahn, Anja K. Münster-Kühnel, Lars Nitschke

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol. 119, no. 25, pp. e2201129119

Sialic acids (Sias) on the B cell membrane are involved in cell migration, in the control of the complement system and, as sialic acid–binding immunoglobulin-like lectin (Siglec) ligands, in the regulation of cellular signaling. We studied the role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e33d6638733242bb0050825fdebd85d
https://pubmed.ncbi.nlm.nih.gov/35696562

Biochemical and structural studies of target lectin SapL1 from the emerging opportunistic microfungus Scedosporium apiospermum

Autor: Martínez-Alarcón, Dania, Balloy, Viviane, Bouchara, Jean-Philippe, Pieters, Roland, varrot, Annabelle

Publikováno v: 'Scientific Reports ', vol: 11, pages: 16109-1-16109-14 (2021)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11, pp.16109. ⟨10.1038/s41598-021-95008-4⟩
Scientific Reports, 2021, 11, pp.16109. ⟨10.1038/s41598-021-95008-4⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)

International audience; Scedosporium apiospermum is an emerging opportunistic fungal pathogen responsible for life-threatening infections in humans. Host–pathogen interactions often implicate lectins that have become therapeutic targets for the dev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e44e712f9328d6a0654137ef96872346
https://pubmed.ncbi.nlm.nih.gov/34373510

Biochemical and structural studies of target lectin SapL1 from the emerging opportunistic microfungus Scedosporium apiospermum

Publikováno v: Scientific Reports. 11(1):1

Scedosporium apiospermum is an emerging opportunistic fungal pathogen responsible for life-threatening infections in humans. Host-pathogen interactions often implicate lectins that have become therapeutic targets for the development of carbohydrate m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::c447775bfed5c4a667d7606cfd902371
https://hdl.handle.net/1874/418054

Glial response to 17β-estradiol in neonatal rats with excitotoxic brain injury

Autor: Raffaella Moretti, Christiane Charriaut-Marlangue, Pierre Gressens, Jérôme Mairesse, Leslie Schwendimann, Jérémie Dalous, Assia Fafouri, Olivier Baud, Anne-Laure Schang, Didier Chevenne, Marina Colella, Julien Pansiot, Hoa Pham

Publikováno v: Pansiot, J, Pham, H, Dalous, J, Chevenne, D, Colella, M, Schwendimann, L, Fafouri, A, Mairesse, J, Moretti, R, Schang, A-L, Charriaut-Marlangue, C, Gressens, P & Baud, O 2016, ' Glial response to 17β-estradiol in neonatal rats with excitotoxic brain injury ', Experimental Neurology, vol. 282, pp. 56-65 . https://doi.org/10.1016/j.expneurol.2016.05.024
Experimental Neurology, Vol. 282 (2016) pp. 56-65

White-matter injury is the most common cause of the adverse neurodevelopmental outcomes observed in preterm infants. Only few options exist to prevent perinatal brain injury associated to preterm delivery. 17β-estradiol (E2) is the predominant estro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e184f6e04eec96f4f71390795ad18d3
https://doi.org/10.1016/j.expneurol.2016.05.024

Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection

Autor: Tara E Sutherland, Dominik Rückerl, Nicola Logan, Sheelagh Duncan, Thomas A Wynn, Judith E Allen

Publikováno v: Sutherland, T E, Rückerl, D, Logan, N, Duncan, S, Wynn, T A & Allen, J E 2018, ' Ym1 induces RELMα and rescues IL-4Rα deficiency in lung repair during nematode infection ', PLoS Pathogens, vol. 14, no. 11, e1007423 . https://doi.org/10.1371/journal.ppat.1007423
PLoS Pathogens, Vol 14, Iss 11, p e1007423 (2018)

Ym1 and RELMα are established effector molecules closely synonymous with Th2-type inflammation and associated pathology. Here, we show that whilst largely dependent on IL-4Rα signaling during a type 2 response, Ym1 and RELMα also have IL-4Rα-inde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fdc30104cb594467c4da19babd53da78
https://doi.org/10.1371/journal.ppat.1007423