Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Lech Wojtczak"'
Autor:
Peter Schönfeld, Lech Wojtczak
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 6, Pp 943-954 (2016)
Short- and medium-chain fatty acids (SCFAs and MCFAs), independently of their cellular signaling functions, are important substrates of the energy metabolism and anabolic processes in mammals. SCFAs are mostly generated by colonic bacteria and are pr
Externí odkaz:
https://doaj.org/article/32707432dd18488d90553bbda6be1de5
Autor:
Paulo J. Oliveira, Agnieszka Karkucinska-Wieckowska, José A. Teixeira, Lech Wojtczak, Daniel Chavarria, Fernanda Borges, Mariusz R. Wieckowski
Publikováno v:
Current Medicinal Chemistry. 26:3376-3406
Mitochondria are cytoplasmic double-membraned organelles that are involved in a myriad of key cellular regulatory processes. The loss of mitochondrial function is related to the pathogenesis of several human diseases. Over the last decades, an increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434b54bff10a046ce37307dba0f19148
https://doi.org/10.2174/0929867324666170529101810
https://doi.org/10.2174/0929867324666170529101810
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2310
Mitochondria are the organelles where the most fundamental processes of energy transformation within the cell are located. They are also involved in several processes like apoptosis and autophagy, reactive oxygen species formation, and calcium signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dc9328d8529df8aeaa51f792ba89c30
https://pubmed.ncbi.nlm.nih.gov/34096000
https://pubmed.ncbi.nlm.nih.gov/34096000
Publikováno v:
Methods in Molecular Biology ISBN: 9781071614327
Mitochondria are the organelles where the most fundamental processes of energy transformation within the cell are located. They are also involved in several processes like apoptosis and autophagy, reactive oxygen species formation, and calcium signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53eaac657be6aed13e640ed0f505b04f
https://doi.org/10.1007/978-1-0716-1433-4_7
https://doi.org/10.1007/978-1-0716-1433-4_7
Autor:
Lech Wojtczak, Mariusz R. Więckowski
Publikováno v:
Postępy Biochemii. 62:298-302
An outline of studies on the mitochondrial large conductance permeability pore is presented starting from the early observations in the 1950s on the large amplitude mitochondrial swelling, through the concept of the permeability transition and variou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38562655d75511e4771ceaf490d161aa
https://doi.org/10.18388/pb.2016_29
https://doi.org/10.18388/pb.2016_29
Publikováno v:
Free Radical Biology and Medicine. 47:503-509
Preparations of rat liver mitochondria, but not of brain and heart mitochondria, produce large quantities of reactive oxygen species (ROS) in the presence of palmitoyl-CoA and other long-chain acyl-CoAs. Palmitoyl-CoA inhibited respiration of rat liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d163f416a30ee06de9a4574910e55058
https://doi.org/10.1016/j.freeradbiomed.2009.05.006
https://doi.org/10.1016/j.freeradbiomed.2009.05.006
Publikováno v:
Toxicology and Applied Pharmacology. 231:34-42
The mechanisms of toxic effects of divalent cations of three heavy metals Hg, Cd and Cu in rat ascites hepatoma AS-30D cells cultivated in vitro were compared. It was found that the toxicity of these ions, applied in the micromolar range (10-500 micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436ecc63f0d76b60a098c1d7c934887d
https://doi.org/10.1016/j.taap.2008.03.017
https://doi.org/10.1016/j.taap.2008.03.017
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1757(12):1568-1574
Using AS-30D rat ascites hepatoma cells, we studied the modulating action of various antioxidants, inhibitors of mitochondrial permeability transition pore and inhibitors of the respiratory chain on Cd(2+)-produced cytotoxicity. It was found that Cd(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0788f0abe0b54b407c56b839c3104e83
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1657(2-3):151-163
Effects of N-acylethanolamines (NAEs): N-arachidonoylethanolamine (anandamide), N-oleoylethanolamine and N-palmitoylethanolamine, on energy coupling and permeability of rat heart mitochondria were investigated. In nominally Ca2+-free media, these com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ed4b8bc03d750b85ff221fe1b39cc4
Publikováno v:
FEBS Letters. 569:169-172
We have previously observed (summarized in BioFactors 17 (2003) 61) that pantothenic acid, pantothenol and other derivatives that are precursors of CoA protect cells and whole organs against peroxidative damage by increasing the content of cell gluta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4cb3122672c02d525f1642123ddc19
https://doi.org/10.1016/j.febslet.2004.05.044
https://doi.org/10.1016/j.febslet.2004.05.044