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Ibuprofen is deleterious for the development of first trimester human fetal ovary ex vivo

Autor: Leverrier-Penna, S., Mitchell, R. T., Becker, E., Lecante, L., Ben Maamar, M., Homer, N., Lavoue, V., Kristensen, D. M., Dejucq-Rainsford, N., Jegou, B., Mazaud-Guittot, S.

Publikováno v: Human Reproduction
Human Reproduction, Oxford University Press (OUP), 2018, 33 (3), pp.482-493. ⟨10.1093/humrep/dex383⟩
Human Reproduction, 2018, 33 (3), pp.482-493. ⟨10.1093/humrep/dex383⟩
Leverrier-Penna, S, Mitchell, R, Becker, E B E, Lecante, L, Ben Maamar, M, Homer, N, Lavoué, V, Kristensen, D M, Dejucq-Rainsford, N, Jégou, B & Mazaud-guittot, S 2018, ' Ibuprofen is deleterious for the development of first trimester human fetal ovary ex vivo ', Human Reproduction . https://doi.org/10.1093/humrep/dex383
Leverrier-Penna, S, Mitchell, R T, Becker, E, Lecante, L, Ben Maamar, M, Homer, N, Lavoue, V, Kristensen, D M, Dejucq-Rainsford, N, Jegou, B & Mazaud-Guittot, S 2018, ' Ibuprofen is deleterious for the development of first trimester human fetal ovary ex vivo ', Human Reproduction, vol. 33, no. 3, pp. 482-493 . https://doi.org/10.1093/humrep/dex383

International audience; STUDY QUESTION Does ibuprofen use during the first trimester of pregnancy interfere with the development of the human fetal ovary? SUMMARY ANSWER In human fetuses, ibuprofen exposure is deleterious for ovarian germ cells. WHAT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ab73175ee48b06363417980ee3845888
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01739999/file/dex383.pdf

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Ibuprofen is deleterious for the development of first trimester human fetal ovary ex vivo.

Autor: Leverrier-Penna S; Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail) UMR_S 1085, F-35000Rennes, France., Mitchell RT; MRC Centre for Reproductive Health, University of Edinburgh, The Queens Medical Research Institute, 47 Little France Crescent, EdinburghEH16 4TJ, UK., Becker E; Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail) UMR_S 1085, F-35000Rennes, France., Lecante L; Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail) UMR_S 1085, F-35000Rennes, France., Ben Maamar M; Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail) UMR_S 1085, F-35000Rennes, France., Homer N; MRC Centre for Reproductive Health, University of Edinburgh, The Queens Medical Research Institute, 47 Little France Crescent, EdinburghEH16 4TJ, UK., Lavoué V; CHU Rennes, Service Gynécologie et Obstetrique, F-35000Rennes, France., Kristensen DM; Novo Nordisk Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Dejucq-Rainsford N; Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail) UMR_S 1085, F-35000Rennes, France., Jégou B; Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail) UMR_S 1085, F-35000 Rennes, France.; EHESP-School of Public health, Avenue du Professeur Léon-Bernard, F-35043 Rennes, France., Mazaud-Guittot S; Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail) UMR_S 1085, F-35000Rennes, France.

Publikováno v: Human reproduction (Oxford, England) [Hum Reprod] 2018 Mar 01; Vol. 33 (3), pp. 482-493.