Efficacy and Safety of Pacritinib vs Placebo for Patients With Severe COVID-19: A Phase 2 Randomized Clinical Trial.

Autor: Cafardi J; The Carl and Edyth Lindner Center for Research and Education at The Christ Hospital, Cincinnati, Ohio., Miller C; Ascension St Agnes Cancer Institute, Baltimore, Maryland., Terebelo H; Ascension St John Newland Medical Associates, Southfield, Michigan., Tewell C; Ascension Medical Group St Vincent Carmel Infectious Disease, Carmel, Indiana., Benzaquen S; Albert Einstein Medical Center, Philadelphia, Pennsylvania., Park D; Providence St Jude Medical Center, Providence Medical Foundation, Fullerton, California., Egan P; Lifespan Cancer Institute, Rhode Island Hospital, Providence., Lebovic D; Ascension St John Hospital, Detroit, Michigan., Pettit K; Bone Marrow Transplant & Leukemia Clinic, C. S. Mott Children's Hospital, Ann Arbor, Michigan., Whitman E; Atlantic Health System, Morristown, New Jersey., Tremblay D; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Feld J; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Buckley S; CTI BioPharma, Seattle, Washington., Roman-Torres K; CTI BioPharma, Seattle, Washington., Smith J; CTI BioPharma, Seattle, Washington., Craig A; CTI BioPharma, Seattle, Washington., Mascarenhas J; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

Publikováno v: JAMA network open [JAMA Netw Open] 2022 Dec 01; Vol. 5 (12), pp. e2242918. Date of Electronic Publication: 2022 Dec 01.

More than an Incidentaloma: The Nonreportable NIPT.

Autor: Jay AM; Ascension St. John Genetics, 19229 Mack Ave, Grosse Pointe, MI 48236, USA., Mason B; Ascension St. John Obstetrics and Gynecology, 22151 Moross Rd I, Suite, Grosse Pointe, MI 48236, USA., Lebovic D; Ascension St. John, Hematology and Oncology, 19229 Mack Ave, Grosse Pointe, MI 48236, USA., Chuba P; Ascension St. John Macomb, Radiation Oncology, 11800 Twelve Mile Rd, Warren, MI 48093, USA.

Publikováno v: Case reports in obstetrics and gynecology [Case Rep Obstet Gynecol] 2022 Apr 30; Vol. 2022, pp. 2496057. Date of Electronic Publication: 2022 Apr 30 (Print Publication: 2022).

Carfilzomib and dexamethasone versus bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma (ENDEAVOR): And randomised, phase 3, open-label, multicentre study

Autor: Dimopoulos, Ma, Moreau, P, Palumbo, A, Joshua, D, Pour, L, Hájek, R, Facon, T, Ludwig, H, Oriol, A, Goldschmidt, H, Rosiñol, L, Straub, J, Suvorov, A, Araujo, C, Rimashevskaya, E, Pika, T, Gaidano, G, Weisel, K, Goranova Marinova, V, Schwarer, A, Minuk, L, Masszi, T, Karamanesht, I, Offidani, M, Hungria, V, Spencer, A, Orlowski, Rz, Gillenwater, Hh, Mohamed, N, Feng, S, Chng, Wj, ENDEAVOR Investigators: Leahy, M, Kerridge, I, Durrant, S, Cooney, J, Horvath, N, Rowlings, P, Hahn, U, Fay, K, Renwick, W, Quach, H, Taylor, K, Ho, Sj, Johnston, A, Kasparu, H, Delforge, M, Schots, H, Vekemans, Mc, Offner, F, Wu, Kl, Doyen, C, Bittencourt, R, Duarte, G, Maiolino, A, Schaan, M, Scheliga, A, Zadra, C, Gercheva, L, Mihaylov, G, Grudeva Popova, Z, Sandhu, I, Reiman, A, Kanjeekal, S, Dueck, G, Leblanc, R, Tay, J, White, D, Maisnar, V, Scudla, V, Gregora, E, Hajek, R, Stoppa, Am, Karlin, L, Garderet, L, Fermand, Jp, Lenain, P, Rigaudeau, S, Eveillard, Jr, Escoffre Barbe, M, Knop, S, Kropff, M, Rollig, C, Munder, M, Langer, C, Mugge, Lo, Hanel, M, Niederwieser, D, Dimopoulos, M, Egyed, M, Szomor, A, Borbenyi, Z, Illes, A, Yehuda, Db, Benyamini, N, Nagler, A, Mittleman, M, Izhar, H, Cavo, M, De Fabritiis, P, Petrini, Mario, Foa, R, Gobbi, M, Rossi, G, Guglielmelli, T, Lazzaro, A, Musto, P, Gozzetti, A, Takazako, N, Izumi, T, Chou, T, Ozaki, S, Hatake, K, Suzuki, K, Uike, N, Asakura, S, Kosugi, H, Handa, H, Matsumoto, M, Tobinai, K, Iida, S, Kizaki, M, Miyamoto, T, Shibayama, H, Ando, K, Ishikawa, T, Ishida, T, Sugiura, I, Izutsu, K, Taniwaki, M, Lee, Jh, Kim, K, Kim, Js, Min, Ck, Yoon, Ss, Lee, Jo, Suh, C, Simpson, D, Ganly, P, Blacklock, H, Doocey, R, Chiruka, S, Hellmann, A, Gornik, S, Komarnicki, M, Malgorzata, Calbecka, Grosicki, S, Jurczyszyn, A, Stoia, R, Gheorghita, E, Danaila, Cd, Abdulkadyrov, K, Zaritskiy, A, Andreeva, N, Balakireva, T, Podoltseva, E, Rossiev, V, Pristupa, A, Hsieh, Ws, Gopalakrishnan, Sk, Mistrik, M, Rocafiguera, Ao, Mateos, V, Rubia, J, Dachs, Lr, Sanchez, Jm, Alegre, A, Bargay, J, de Oteyza JP, Martinez, J, Chen, Ty, Lin, Tl, Liu, Jh, Wang, Mc, Yeh, Sp, Huang, Sy, Vinnyk, Y, Kriachok, I, Pylypenko, H, Shparyk, Y, Kaplan, P, Karamanesht, L, Rekhtman, G, Romanyuk, N, Kaiser, M, Mehta, A, Williams, C, Basu, S, Rabin, N, Ramasamy, K, Hunter, H, Tholouli, E, Lebovic, D, Siegel, D, Wang, M, Niesvizky, R, Kovacsovics, T, Hurd, D, Gabrail, N, Matous, J, Pendergrass, K, Agrawal, M, Boccia, R, Chandra, S, Kassim, A, Stanisic, S, Coleman, M, Gersten, T, Braunschweig, I, Chowdhury, S, Sahovic, E.

BACKGROUND: Bortezomib with dexamethasone is a standard treatment option for relapsed or refractory multiple myeloma. Carfilzomib with dexamethasone has shown promising activity in patients in this disease setting. The aim of this study was to compar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba65034270a7f1716f664ed2276b519e
http://hdl.handle.net/11573/935153

In vivo CAR T cell therapy against angioimmunoblastic T cell lymphoma.

Autor: Krug, Adrien^1,2 (AUTHOR), Saidane, Aymen^1,2 (AUTHOR), Martinello, Chiara¹ (AUTHOR), Fusil, Floriane³ (AUTHOR), Michels, Alexander⁴ (AUTHOR), Buchholz, Christian J.^4,5 (AUTHOR), Ricci, Jean-Ehrland^1,2 (AUTHOR), Verhoeyen, Els^1,2,3 (AUTHOR) els.verhoeyen@unice.fr

Publikováno v: Journal of Experimental & Clinical Cancer Research (17569966). 9/14/2024, Vol. 43 Issue 1, p1-18. 18p.

Ubiquitination and deubiquitination in cancer: from mechanisms to novel therapeutic approaches.

Autor: Liu, Fangfang^1,2 (AUTHOR), Chen, Jingyu³ (AUTHOR), Li, Kai⁴ (AUTHOR), Li, Haochen⁴ (AUTHOR), Zhu, Yiyi⁴ (AUTHOR), Zhai, Yubo⁵ (AUTHOR), Lu, Bingbing⁵ (AUTHOR), Fan, Yanle² (AUTHOR), Liu, Ziyue⁵ (AUTHOR), Chen, Xiaojie⁶ (AUTHOR), Jia, Xuechao⁷ (AUTHOR) xcjia@hci-cn.org, Dong, Zigang^1,2,5 (AUTHOR) dongzg@zzu.edu.cn, Liu, Kangdong^1,5 (AUTHOR) kdliu@zzu.edu.cn

Publikováno v: Molecular Cancer. 7/25/2024, Vol. 23 Issue 1, p1-50. 50p.