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Correction: Convergent synthesis of thiodiazole dioxides from simple ketones and amines through an unusual nitrogen-migration mechanism.

Autor: Punjajom K; Department of Chemistry, University of California Berkeley CA 94720 USA rsarpong@berkeley.edu., Sinclair PP; Department of Chemistry, University of California Berkeley CA 94720 USA rsarpong@berkeley.edu., Saha I; Janssen Research and Development San Diego California 92121 USA pgarciar@its.jnj.com terry.lebold@gmail.com., Seierstad M; Janssen Research and Development San Diego California 92121 USA pgarciar@its.jnj.com terry.lebold@gmail.com., Ameriks MK; Janssen Research and Development San Diego California 92121 USA pgarciar@its.jnj.com terry.lebold@gmail.com., García-Reynaga P; Janssen Research and Development San Diego California 92121 USA pgarciar@its.jnj.com terry.lebold@gmail.com., Lebold TP; Janssen Research and Development San Diego California 92121 USA pgarciar@its.jnj.com terry.lebold@gmail.com., Sarpong R; Department of Chemistry, University of California Berkeley CA 94720 USA rsarpong@berkeley.edu.

Publikováno v: Chemical science [Chem Sci] 2024 Jun 24; Vol. 15 (28), pp. 11145-11147. Date of Electronic Publication: 2024 Jun 24 (Print Publication: 2024).

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Akademický článek

Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions.

Autor: McCarver S; Janssen Research and Development, San Diego, California 92121-1126, United States., Hanna L; Janssen Research and Development, San Diego, California 92121-1126, United States., Samant A; Janssen Research and Development, San Diego, California 92121-1126, United States., Thompson AA; Janssen Research and Development, San Diego, California 92121-1126, United States., Seierstad M; Janssen Research and Development, San Diego, California 92121-1126, United States., Saha A; Janssen Research and Development, San Diego, California 92121-1126, United States., Wu D; Janssen Research and Development, San Diego, California 92121-1126, United States., Lord B; Janssen Research and Development, San Diego, California 92121-1126, United States., Sutton SW; Janssen Research and Development, San Diego, California 92121-1126, United States., Shah V; Janssen Research and Development, San Diego, California 92121-1126, United States., Milligan CM; Janssen Research and Development, San Diego, California 92121-1126, United States., Wennerholm M; Janssen Research and Development, San Diego, California 92121-1126, United States., Shelton J; Janssen Research and Development, San Diego, California 92121-1126, United States., Lebold TP; Janssen Research and Development, San Diego, California 92121-1126, United States., Shireman BT; Janssen Research and Development, San Diego, California 92121-1126, United States.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2024 Mar 07; Vol. 15 (4), pp. 486-492. Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).

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Akademický článek

Synthesis of Highly Functionalized 4-Iodo-7-azaindazoles via Condensation/Diels-Alder/Retro-Diels-Alder Cyclization of Iodoalkynones and 2-Hydrazineylpyrimidines.

Autor: Swift EC; Discovery Process Research, Janssen R&D, San Diego, California 92121, United States., Sales ZS; Discovery Process Research, Janssen R&D, San Diego, California 92121, United States., Wu D; Discovery Chemistry, Janssen R&D, San Diego, California 92121, United States., Matviitsuk A; Discovery Process Research, Janssen R&D, San Diego, California 92121, United States., Pippel DJ; Discovery Process Research, Janssen R&D, San Diego, California 92121, United States., Lebold TP; Discovery Chemistry, Janssen R&D, San Diego, California 92121, United States.

Publikováno v: Organic letters [Org Lett] 2023 Dec 08; Vol. 25 (48), pp. 8711-8715. Date of Electronic Publication: 2023 Nov 22.

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Akademický článek

Convergent synthesis of thiodiazole dioxides from simple ketones and amines through an unusual nitrogen-migration mechanism.

Publikováno v: Chemical science [Chem Sci] 2023 Nov 27; Vol. 15 (1), pp. 328-335. Date of Electronic Publication: 2023 Nov 27 (Print Publication: 2023).

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Akademický článek

Skeletal Editing Approach to Bridge-Functionalized Bicyclo[1.1.1]pentanes from Azabicyclo[2.1.1]hexanes.

Autor: Wright BA; Department of Chemistry, University of California, Berkeley, California 94720, United States., Matviitsuk A; Janssen Research and Development, San Diego, California 92121, United States., Black MJ; Department of Chemistry, University of California, Berkeley, California 94720, United States., García-Reynaga P; Janssen Research and Development, San Diego, California 92121, United States., Hanna LE; Janssen Research and Development, San Diego, California 92121, United States., Herrmann AT; Janssen Research and Development, San Diego, California 92121, United States., Ameriks MK; Janssen Research and Development, San Diego, California 92121, United States., Sarpong R; Department of Chemistry, University of California, Berkeley, California 94720, United States., Lebold TP; Janssen Research and Development, San Diego, California 92121, United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2023 May 24; Vol. 145 (20), pp. 10960-10966. Date of Electronic Publication: 2023 May 05.

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Akademický článek

Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans.

Autor: Salvadore G; Janssen Research & Development, LLC, Titusville, NJ, USA., Bonaventure P; Janssen Research & Development, LLC, San Diego, CA, USA. pbonave1@its.jnj.com., Shekhar A; Departments of Psychiatry, and Pharmacology, Indiana University, School of Medicine, Indianapolis, IN, USA., Johnson PL; Department of Anatomy, Physiology and Cell Biology, Indiana University, School of Medicine, Indianapolis, IN, USA., Lord B; Janssen Research & Development, LLC, San Diego, CA, USA., Shireman BT; Janssen Research & Development, LLC, San Diego, CA, USA., Lebold TP; Janssen Research & Development, LLC, San Diego, CA, USA., Nepomuceno D; Janssen Research & Development, LLC, San Diego, CA, USA., Dugovic C; Janssen Research & Development, LLC, San Diego, CA, USA., Brooks S; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands., Zuiker R; Centre for Human Drug Research, Leiden, The Netherlands., Bleys C; Janssen Research & Development, LLC, Beerse, Belgium., Tatikola K; Janssen Scientific Affairs, LLC, Titusville, NJ, USA., Remmerie B; Janssen Research & Development, LLC, Beerse, Belgium., Jacobs GE; Centre for Human Drug Research, Leiden, The Netherlands.; Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands., Schruers K; Research School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands., Moyer J; Janssen Research & Development, LLC, Titusville, NJ, USA., Nash A; Janssen Scientific Affairs, LLC, Titusville, NJ, USA., Van Nueten LGM; Janssen Research & Development, LLC, Beerse, Belgium., Drevets WC; Janssen Research & Development, LLC, San Diego, CA, USA.

Publikováno v: Translational psychiatry [Transl Psychiatry] 2020 Sep 07; Vol. 10 (1), pp. 308. Date of Electronic Publication: 2020 Sep 07.

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Akademický článek

A Benzyne Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossonidine (Davisine).

Autor: Kou KGM; Department of Chemistry , University of California, Berkeley , Berkeley , California 94720 , United States., Pflueger JJ; Department of Chemistry , University of California, Berkeley , Berkeley , California 94720 , United States., Kiho T; Department of Chemistry , University of California, Berkeley , Berkeley , California 94720 , United States., Morrill LC; Department of Chemistry , University of California, Berkeley , Berkeley , California 94720 , United States., Fisher EL; Department of Chemistry , University of California, Berkeley , Berkeley , California 94720 , United States., Clagg K; Department of Chemistry , University of California, Berkeley , Berkeley , California 94720 , United States., Lebold TP; Department of Chemistry , University of California, Berkeley , Berkeley , California 94720 , United States., Kisunzu JK; Department of Chemistry & Biochemistry , Colorado College , Colorado Springs , Colorado 80903 , United States., Sarpong R; Department of Chemistry , University of California, Berkeley , Berkeley , California 94720 , United States.

Publikováno v: Journal of the American Chemical Society [J Am Chem Soc] 2018 Jul 05; Vol. 140 (26), pp. 8105-8109. Date of Electronic Publication: 2018 Jun 19.

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