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Repairing a deleterious domestication variant in a floral regulator gene of tomato by base editing.

Autor: Glaus AN; Department of Plant Molecular Biology, University of Lausanne, Lausanne, Switzerland.; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland., Brechet M; Department of Plant Molecular Biology, University of Lausanne, Lausanne, Switzerland.; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland., Swinnen G; Department of Plant Molecular Biology, University of Lausanne, Lausanne, Switzerland.; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland., Lebeigle L; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland., Iwaszkiewicz J; Molecular Modeling Group, Swiss Institute of Bioinformatics, Lausanne, Switzerland., Ambrosini G; Bioinformatics Competence Centre, University of Lausanne, Lausanne, Switzerland.; Bioinformatics Competence Centre, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Julca I; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland., Zhang J; Boyce Thompson Institute for Plant Research, Ithaca, NY, USA., Roberts R; Boyce Thompson Institute for Plant Research, Ithaca, NY, USA., Iseli C; Bioinformatics Competence Centre, University of Lausanne, Lausanne, Switzerland.; Bioinformatics Competence Centre, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Guex N; Bioinformatics Competence Centre, University of Lausanne, Lausanne, Switzerland.; Bioinformatics Competence Centre, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Jiménez-Gómez J; Centro de Biotecnología y Genómica de Plantas (CBGP), Madrid, Spain., Glover N; SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland., Martin GB; Boyce Thompson Institute for Plant Research, Ithaca, NY, USA.; Plant Pathology and Plant-Microbe Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, NY, USA., Strickler S; Boyce Thompson Institute for Plant Research, Ithaca, NY, USA.; Plant Science and Conservation Chicago Botanic Garden, Glencoe, IL, USA.; Plant Biology and Conservation Program Northwestern University, Evanston, IL, USA., Soyk S; Department of Plant Molecular Biology, University of Lausanne, Lausanne, Switzerland. sebastian.soyk@unil.ch.; Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland. sebastian.soyk@unil.ch.

Publikováno v: Nature genetics [Nat Genet] 2025 Jan 02. Date of Electronic Publication: 2025 Jan 02.