Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Lebaron C. Agostini"'
Autor:
Grace A. McCarthy, Aditi Jain, Roberto Di Niro, Christopher W. Schultz, Wei Jiang, Charles J Yeo, Jessica Bowers, Jennifer Finan, Kelly Rhodes, Lou Casta, Vivi Hou, Anthony Stefanoni, Samantha Z. Brown, Avinoam Nevler, Lebaron C. Agostini, Lori Getts, Robert Getts, Jonathan R. Brody
Publikováno v:
Translational Oncology, Vol 32, Iss , Pp 101662- (2023)
Introduction: Standard-of-care systemic chemotherapies for pancreatic ductal adenocarcinoma (PDAC) currently have limited clinical benefits, in addition to causing adverse side effects in many patients. One factor known to contribute to the poor chem
Externí odkaz:
https://doaj.org/article/1a3343d576a846809073e9eb6d5af670
Publikováno v:
BioTechniques, Vol 68, Iss 2, Pp 101-105 (2020)
The use of RNA electrophoretic mobility shift assays (REMSAs) for analysis of RNA–protein interactions have been limited to lengthy assay time and qualitative assessment. To vastly improve assay efficiency, feasibility and quality of data procured
Externí odkaz:
https://doaj.org/article/30b7111d698a44e8a20a63bfc89643d0
Autor:
Karen M. Bussard, Jonathan R. Brody, Gang Ning, Lebaron C. Agostini, Manish Neupane, Alison B. Shupp
Supplemental Table 1. Antibodies used for immunofluorescence Supplemental Table 2. Antibodies used for western blotting Supplemental Figure 1: EO-MCF7 sEVs decrease MCF7 proliferation. Supplemental Figure 2: Primary EO sEVs regulate MDA-MB-231 S-phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cd35ba7596b9517388dda9c1c10ffc
https://doi.org/10.1158/1541-7786.22527006
https://doi.org/10.1158/1541-7786.22527006
Autor:
Jonathan R. Brody, Charles J. Yeo, Karen M. Bussard, Grace McCarthy, Avinoam Nevler, Alison Shupp, Aditi Jain, Lebaron C. Agostini
Figure S3 shows IHC staining and quantification of Ki67 and phospho-h2ax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0a2c19185bdfebb95e3bdee6adbdb3
https://doi.org/10.1158/1541-7786.22526366
https://doi.org/10.1158/1541-7786.22526366
Autor:
Jonathan R. Brody, William H. Gmeiner, Charles J. Yeo, Komaraiah Palle, Talia Golan, Lebaron C. Agostini, Avinoam Nevler, Chinnadurai Mani, Aditi Jain, Alex O. Haber
AraC-FdUMP[10] (CF10) is a second-generation polymeric fluoropyrimidine that targets both thymidylate synthase (TS), the target of 5-fluorouracil (5-FU), and DNA topoisomerase 1 (Top1), the target of irinotecan, two drugs that are key components of F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbeb761e931f5550b765a86612d1904c
https://doi.org/10.1158/1541-7786.c.6545126.v1
https://doi.org/10.1158/1541-7786.c.6545126.v1
Autor:
Jonathan R. Brody, Charles J. Yeo, Karen M. Bussard, Grace McCarthy, Avinoam Nevler, Alison Shupp, Aditi Jain, Lebaron C. Agostini
The DNA damage response (DDR) pathway sets the stage for tumorigenesis and provides both an opportunity for drug efficacy and resistance. Therapeutic approaches to target the DDR pathway include aiming to increase the efficacy of cytotoxic chemothera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfbb755a0b43ace0d442549e53ecf603
https://doi.org/10.1158/1541-7786.c.6545066.v1
https://doi.org/10.1158/1541-7786.c.6545066.v1
Autor:
Jonathan R. Brody, William H. Gmeiner, Charles J. Yeo, Komaraiah Palle, Talia Golan, Lebaron C. Agostini, Avinoam Nevler, Chinnadurai Mani, Aditi Jain, Alex O. Haber
S1. (A) Representative graph of 5-day picogreen survival assay with PDX139, a patient derived xenograft line. (B) Representative images of 10-day colony growth inhibition assays with crystal violet staining in indicated PDAC cell lines. (C) Graph of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c297fc72f9734b6d4226904ebc294ef
https://doi.org/10.1158/1541-7786.22526537.v1
https://doi.org/10.1158/1541-7786.22526537.v1
Autor:
Karen M. Bussard, Jonathan R. Brody, Gang Ning, Lebaron C. Agostini, Manish Neupane, Alison B. Shupp
Bone is a common site of cancer metastasis, including cancers such as breast, prostate, and multiple myeloma. Disseminated tumor cells (DTC) shed from a primary tumor may travel to bone and can survive undetected for years before proliferating to for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11457c1781993ac518c4e8aaef1bfa26
https://doi.org/10.1158/1541-7786.c.6545289.v1
https://doi.org/10.1158/1541-7786.c.6545289.v1
Autor:
Jonathan R. Brody, Allan M. Jordan, Dominic I. James, Donald Ogilvie, Michael J. Pishvaian, Talia Golan, Kenneth P. Olive, Jordan M. Winter, Charles J. Yeo, Dikla Atias, Yulia Glick Gorman, Chani Stossel, Maria Raitses-Gurevich, Ian D. Waddell, Kate M. Smith, Cinthya Yabar Lowder, Christopher W. Schultz, Joseph Cozzitorto, Avinoam Nevler, AnnJosette Ramirez, Saswati N. Chand, Grace A. McCarthy, Lebaron C. Agostini, Aditi Jain
Supplementary Fig S7 describes western blot and RTPCR of PARG in modified shPARG cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12baac012d9c7c055a7134059d275323
https://doi.org/10.1158/0008-5472.22421175
https://doi.org/10.1158/0008-5472.22421175
Autor:
Jonathan R. Brody, Allan M. Jordan, Dominic I. James, Donald Ogilvie, Michael J. Pishvaian, Talia Golan, Kenneth P. Olive, Jordan M. Winter, Charles J. Yeo, Dikla Atias, Yulia Glick Gorman, Chani Stossel, Maria Raitses-Gurevich, Ian D. Waddell, Kate M. Smith, Cinthya Yabar Lowder, Christopher W. Schultz, Joseph Cozzitorto, Avinoam Nevler, AnnJosette Ramirez, Saswati N. Chand, Grace A. McCarthy, Lebaron C. Agostini, Aditi Jain
Patients with metastatic pancreatic ductal adenocarcinoma (PDAC) have an average survival of less than 1 year, underscoring the importance of evaluating novel targets with matched targeted agents. We recently identified that poly (ADP) ribose glycohy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2caad1a0117fff7a23cc205bcb261f20
https://doi.org/10.1158/0008-5472.c.6510855.v1
https://doi.org/10.1158/0008-5472.c.6510855.v1