Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Leath A Tonkin"'
Autor:
Susan E Lott, Jacqueline E Villalta, Gary P Schroth, Shujun Luo, Leath A Tonkin, Michael B Eisen
Publikováno v:
PLoS Biology, Vol 9, Iss 2, p e1000590 (2011)
When Drosophila melanogaster embryos initiate zygotic transcription around mitotic cycle 10, the dose-sensitive expression of specialized genes on the X chromosome triggers a sex-determination cascade that, among other things, compensates for differe
Externí odkaz:
https://doaj.org/article/ad0d851dd23c428091d5041bc13a2c8e
Autor:
Robert K Bradley, Xiao-Yong Li, Cole Trapnell, Stuart Davidson, Lior Pachter, Hou Cheng Chu, Leath A Tonkin, Mark D Biggin, Michael B Eisen
Publikováno v:
PLoS Biology, Vol 8, Iss 3, p e1000343 (2010)
Changes in gene expression play an important role in evolution, yet the molecular mechanisms underlying regulatory evolution are poorly understood. Here we compare genome-wide binding of the six transcription factors that initiate segmentation along
Externí odkaz:
https://doaj.org/article/bfe81bb20dd34582b08f1d3cc52607fd
Autor:
Brenda L. Bass, Thomas M Brodigan, Michael Krause, Leath A. Tonkin, Lisa Saccomanno, Daniel P. Morse
Publikováno v:
The EMBO Journal. 21:6025-6035
Here we take advantage of the well-characterized and simple nervous system of Caenorhabditis elegans to further our understanding of the functions of RNA editing. We describe the two C.elegans ADAR genes, adr-1 and adr-2, and characterize strains con
Autor:
Maarten H.K. Linskens, Walter Funk, Kaylene J. Chambers, Leath A. Tonkin, Edwin Chang, Dawne N. Shelton
Publikováno v:
Gene, 218(1). Elsevier
We have identified and cloned a cDNA encoding a new member of the monooxygenase family of enzymes. This novel enzyme, which we call MOX (monooxygenase X; unknown substrate) is a clear sequence homologue of the enzyme dopamine b-hydroxylase (DBH ). MO
Autor:
Maarten H.K. Linskens, Shahin M. Saati, William H. Andrews, Bryant Villeponteau, Junli Feng, Walter Funk, Brett E. Enlow, Leath A. Tonkin
Publikováno v:
Nucleic Acids Research, 23(16). Oxford University Press
Recently, a novel PCR-based technique, differential display (DD), has facilitated the study of differentially expressed genes at the mRNA level. We report here an improved version of DD, which we call Enhanced Differential Display (EDD). We have modi
Autor:
Mani Yahyavi, Leath A. Tonkin, Anne Slavotinek, Jason Flannick, Elliott H. Sherr, Jiang Li, Adele Schneider, Nelson Lopez Jimenez, Tanya Bardakjian
Publikováno v:
BMC Medical Genetics, Vol 12, Iss 1, p 172 (2011)
BMC Medical Genetics
Lopez Jimenez, Nelson; Flannick, Jason; Yahyavi, Mani; Li, Jiang; Bardakjian, Tanya; Tonkin, Leath; et al.(2011). Targeted next-generation sequencing in anophthalmia and microphthalmia patients confirms SOX2, OTX2 and FOXE3 mutations. BMC Medical Genetics, 12(1), 172. doi: http://dx.doi.org/10.1186/1471-2350-12-172. Retrieved from: http://www.escholarship.org/uc/item/6m4912xq
BMC Medical Genetics
Lopez Jimenez, Nelson; Flannick, Jason; Yahyavi, Mani; Li, Jiang; Bardakjian, Tanya; Tonkin, Leath; et al.(2011). Targeted next-generation sequencing in anophthalmia and microphthalmia patients confirms SOX2, OTX2 and FOXE3 mutations. BMC Medical Genetics, 12(1), 172. doi: http://dx.doi.org/10.1186/1471-2350-12-172. Retrieved from: http://www.escholarship.org/uc/item/6m4912xq
Background Anophthalmia/microphthalmia (A/M) is caused by mutations in several different transcription factors, but mutations in each causative gene are relatively rare, emphasizing the need for a testing approach that screens multiple genes simultan
Autor:
Jacqueline E. Villalta, Michael B. Eisen, Leath A. Tonkin, Gary P. Schroth, Susan E. Lott, Shujun Luo
Publikováno v:
PLoS biology, vol 9, iss 2
PLoS Biology, Vol 9, Iss 2, p e1000590 (2011)
PLoS Biology
Lott, SE; Villalta, JE; Schroth, GP; Luo, S; Tonkin, LA; & Eisen, MB. (2011). Noncanonical compensation of zygotic X transcription in early Drosophila melanogaster development revealed through single-embryo RNA-Seq. PLoS Biology, 9(2). doi: 10.1371/journal.pbio.1000590. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7g09z2t1
PLoS Biology, Vol 9, Iss 2, p e1000590 (2011)
PLoS Biology
Lott, SE; Villalta, JE; Schroth, GP; Luo, S; Tonkin, LA; & Eisen, MB. (2011). Noncanonical compensation of zygotic X transcription in early Drosophila melanogaster development revealed through single-embryo RNA-Seq. PLoS Biology, 9(2). doi: 10.1371/journal.pbio.1000590. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7g09z2t1
When Drosophila melanogaster embryos initiate zygotic transcription around mitotic cycle 10, the dose-sensitive expression of specialized genes on the X chromosome triggers a sex-determination cascade that, among other things, compensates for differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7b55ba50e1d9e2abce5d7d32a1c213
https://escholarship.org/uc/item/7g09z2t1
https://escholarship.org/uc/item/7g09z2t1
Autor:
Mark D. Biggin, Xiao-Yong Li, Cole Trapnell, Michael B. Eisen, Hou Cheng Chu, Lior Pachter, Stuart M. Davidson, Robert K. Bradley, Leath A. Tonkin
Publikováno v:
PLoS Biology
PLoS Biology, Vol 8, Iss 3, p e1000343 (2010)
PLoS Biology, Vol 8, Iss 3, p e1000343 (2010)
Genome-wide comparison of transcription factor binding between related Drosophila species highlights how sequence changes affect the biochemical events that underlie animal development.
Changes in gene expression play an important role in evolut
Changes in gene expression play an important role in evolut
Autor:
Leath A. Tonkin, Kathleen Collins, Brandon Hogstad, Ravi Sachidanandam, Colin D. Malone, Gregory J. Hannon, Mary T. Couvillion, Suzanne R. Lee
PAZ/PIWI domain (PPD) proteins carrying small RNAs (sRNAs) function in gene and genome regulation. The ciliate Tetrahymena thermophila encodes numerous PPD proteins exclusively of the Piwi clade. We show that the three Tetrahymena Piwi family protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ce52f4a64727a2ed2db8ce4f10bbdf
https://europepmc.org/articles/PMC2751968/
https://europepmc.org/articles/PMC2751968/