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pro vyhledávání: '"Leanza Liu"'
Autor:
Anthony Zaki, Israel Hodish, Dennis Larkin, Leena Haataja, Peter Arvan, Leanza Liu, Ahmed B. Al-Khafaji, Afaf Absood, Ming Liu
Publikováno v:
Diabetes
OBJECTIVE Endoplasmic reticulum (ER) stress has been described in pancreatic β-cells after onset of diabetes—a situation in which failing β-cells have exhausted available compensatory mechanisms. Herein we have compared two mouse models expressin
Autor:
Ming Liu, Leanza Liu, Aaron M. Adams, Dennis Larkin, Israel Hodish, Gautam Rajpal, Ronald W. Holz, Peter Arvan
Publikováno v:
Journal of Biological Chemistry. 285:685-694
It has previously been shown that misfolded mutant Akita proinsulin in the endoplasmic reticulum engages directly in protein complexes either with nonmutant proinsulin or with "hProCpepGFP" (human proinsulin bearing emerald-GFP within the C-peptide),