Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Leanne R, Donahue"'
Autor:
Luye An, Dahihm Kim, Leanne R. Donahue, Menansili Abraham Mejooli, Chi-Yong Eom, Nozomi Nishimura, Andrew C. White
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Vitiligo is an autoimmune skin disease caused by cutaneous melanocyte loss. Although phototherapy and T cell suppression therapy have been widely used to induce epidermal re-pigmentation, full pigmentation recovery is rarely achieved due to
Externí odkaz:
https://doaj.org/article/eb02cc32c1ff4d63a42479f825e79c80
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Cellular extrinsic environmental factors contribute to tumour development. Here, the authors show that gastric acid stress stimulates tumour formation from a defined tumour-competent Krt5 + /Krt15 + foregut basal progenitor cell population.
Externí odkaz:
https://doaj.org/article/7869f89b2952464bb4c94fa9d186093f
Autor:
Mridusmita Saikia, Marlena M. Holter, Leanne R. Donahue, Isaac S. Lee, Qiaonan C. Zheng, Journey L. Wise, Jenna E. Todero, Daryl J. Phuong, Darline Garibay, Reilly Coch, Kyle W. Sloop, Adolfo Garcia-Ocana, Charles G. Danko, Bethany P. Cummings
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that potentiates glucose-stimulated insulin secretion. GLP-1 is classically produced by gut L cells; however, under certain circumstances α cells can express the prohormone convertase required f
Externí odkaz:
https://doaj.org/article/d8231da5c1ae478aaa15444e8576fb6f
Autor:
Gerlinde R. Van de Walle, Rebecca M. Harman, Leanne R. Donahue, Arianna P Bartlett, Sanjna P Das, Gat Rauner
Publikováno v:
Cancer and Metastasis Reviews. 40:47-69
Traditional laboratory model organisms are indispensable for cancer research and have provided insight into numerous mechanisms that contribute to cancer development and progression in humans. However, these models do have some limitations, most nota
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47b6dcba348e0cd2ed6139300fb0b951
https://doi.org/10.1007/s10555-020-09930-6
https://doi.org/10.1007/s10555-020-09930-6
Autor:
Rebecca M, Harman, Sanjna P, Das, Arianna P, Bartlett, Gat, Rauner, Leanne R, Donahue, Gerlinde R, Van de Walle
Publikováno v:
Cancer metastasis reviews. 40(1)
Traditional laboratory model organisms are indispensable for cancer research and have provided insight into numerous mechanisms that contribute to cancer development and progression in humans. However, these models do have some limitations, most nota
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c91f9dd661b565fd375f6ec8e6c6136
https://pubmed.ncbi.nlm.nih.gov/33111160
https://pubmed.ncbi.nlm.nih.gov/33111160
Autor:
Kyle W. Sloop, M. Dodson Michael, Leanne R. Donahue, Karolina E. Zaborska, Darline Garibay, Andrew C. White, Jon Lou, Bethany P. Cummings, Margot H. Weissman, Andrew D. Miller, Seon A. Lee, Erica A. Sloma
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 967-973 (2018)
Cell reports
Cell reports
SUMMARY Bariatric surgery, such as vertical sleeve gastrectomy (VSG), causes high rates of type 2 diabetes remission and remarkable increases in postprandial glucagon-like peptide-1 (GLP-1) secretion. GLP-1 plays a critical role in islet function by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e471a5e60fdd1f288c92ccdce3048e8
http://www.sciencedirect.com/science/article/pii/S2211124718304960
http://www.sciencedirect.com/science/article/pii/S2211124718304960
Publikováno v:
The Journal of investigative dermatology. 140(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21a581fe0efa615a36cfa6eb6be9a90
https://pubmed.ncbi.nlm.nih.gov/31981577
https://pubmed.ncbi.nlm.nih.gov/31981577
Publikováno v:
Journal of visualized experiments : JoVE. (148)
Cutaneous melanoma is well known as the most aggressive skin cancer. Although the risk factors and major genetic alterations continue to be documented with increasing depth, the incidence rate of cutaneous melanoma has shown a rapid and continuous in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff5e26b8d7ae3faa9b9a9548546d49a
https://pubmed.ncbi.nlm.nih.gov/31233013
https://pubmed.ncbi.nlm.nih.gov/31233013
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature communications, vol 10, iss 1
The effective prevention of tumor initiation, especially for potentially inoperable tumors, will be beneficial to obtain an overall higher quality of our health and life. Hence, thorough understanding of the pathophysiological mechanisms of early tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c167f128019379f48d74acf06b708744
http://europepmc.org/articles/PMC6527614
http://europepmc.org/articles/PMC6527614
Publikováno v:
Cancer Research. 80:PR08-PR08
Cutaneous melanoma is the most lethal form of skin cancer. However, the molecular mechanisms and environmental factors that can promote melanoma initiation and development from skin without an identified precursor lesion are not well defined. In thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eae30eb7d9c506d06d43ee85c0728132
https://doi.org/10.1158/1538-7445.mel2019-pr08
https://doi.org/10.1158/1538-7445.mel2019-pr08