Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Leanne Godinho"'
Autor:
Eleni Petridou, Leanne Godinho
Publikováno v:
Annual review of vision science. 8
The vertebrate retina is regarded as a simple part of the central nervous system (CNS) and thus amenable to investigations of the determinants of cell fate. Its five neuronal cell classes and one glial cell class all derive from a common pool of prog
Autor:
Thomas Misgeld, Eleni Petridou, Peter Engerer, Ruben Portugues, Philip R. Williams, Sachihiro C. Suzuki, Leanne Godinho, Takeshi Yoshimatsu
Publikováno v:
Current biology 31(21), 4870-4878.e5 (2021). doi:10.1016/j.cub.2021.08.049
Neuronal identity has long been thought of as immutable, so that once a cell acquires a specific fate, it is maintained for life.1 Studies using the overexpression of potent transcription factors to experimentally reprogram neuronal fate in the mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af134e4bd7aa37e4d25b83de3a9601c4
https://pub.dzne.de/record/163412
https://pub.dzne.de/record/163412
Autor:
Thomas Misgeld, Peter Engerer, Philip R. Williams, Nancy Obeng, Takeshi Yoshimatsu, Prisca Chapouton, Leanne Godinho, Sachihiro C. Suzuki, Benjamin Odermatt
Publikováno v:
EMBO J. 36, 1134-1146 (2017)
The EMBO journal 36(9), 1134-1146 (2017). doi:10.15252/embj.201694230
The EMBO Journal
The EMBO journal 36(9), 1134-1146 (2017). doi:10.15252/embj.201694230
The EMBO Journal
Conventionally, neuronal development is regarded to follow a stereotypic sequence of neurogenesis, migration, and differentiation. We demonstrate that this notion is not a general principle of neuronal development by documenting the timing of mitosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e252e8bd29ec5039148081f9cc2ca0
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=50618
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=50618
Autor:
Jovica Ninkovic, Susanne Sprungala, Lena Glashauser, Birgit Hesl, Leanne Godinho, Maike Fritschle, Kathrin Edelmann, Prisca Chapouton
Publikováno v:
Journal of Comparative Neurology. 521:3099-3115
The zebrafish has recently become a source of new data on the mechanisms of neural stem cell (NSC) maintenance and ongoing neurogenesis in adult brains. In this vertebrate, neurogenesis occurs at high levels in all ventricular regions of the brain, a
Publikováno v:
JoVE journal Developmental Biology(110), 53456 (2016). doi:10.3791/53456
In vivo imaging provides unprecedented access to the dynamic behavior of cellular and subcellular structures in their natural context. Performing such imaging experiments in higher vertebrates such as mammals generally requires surgical access to the
Autor:
Bettina Schmid, Alexander Hruscha, Thomas Misgeld, Christian Haass, Gabriela Plucińska, Dominik Paquet, Leanne Godinho
Publikováno v:
Journal of Neuroscience; Vol 32
The journal of neuroscience 32(46), 16203-16212 (2012). doi:10.1523/JNEUROSCI.1327-12.2012
The journal of neuroscience 32(46), 16203-16212 (2012). doi:10.1523/JNEUROSCI.1327-12.2012
Mitochondria provide ATP, maintain calcium homeostasis, and regulate apoptosis. Neurons, due to their size and complex geometry, are particularly dependent on the proper functioning and distribution of mitochondria. Thus disruptions of these organell
Autor:
Jovica Ninkovic, Timm Schroeder, Magdalena Götz, Gregor A. Pilz, Wieland B. Huttner, Maki Asami, Leanne Godinho
Publikováno v:
Development 138, 5067-5078 (2011)
Successful brain development requires tight regulation of sequential symmetric and asymmetric cell division. Although Pax6 is known to exert multiple roles in the developing nervous system, its role in the regulation of cell division is unknown. Here
Autor:
Graziella Di Cristo, Josh Huang, Leanne Godinho, Rachel O.L. Wong, Joshua L. Morgan, Timm Schubert, Rachel M. Huckfeldt
Publikováno v:
Nature neuroscience
Sensory neurons with common function are often non-randomly arranged and form dendritic territories that exhibit little overlap or tiling. Repulsive homotypic interactions underlie such patterns in cell organization in invertebrate neurons. In mammal
Publikováno v:
Cold Spring Harbor protocols. 2015(10)
With easy access to core facilities or commercial providers of pronuclear injections, generating simple Thy1-XFP transgenic mice (where XFP stands for any fluorescent protein) is now a possibility even for small laboratories. The generation of new Th
Publikováno v:
Cold Spring Harbor protocols. 2015(9)
New generations of Thy1-XFP transgenic mice (where XFP stands for any fluorescent protein) can now be readily generated, given the availability of core facilities or commercial providers of Thy1 pronuclear injections. Here, we provide a protocol for