Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Leanne C. McKay"'
Autor:
Douglas R, Corfield, Leanne C, McKay
Publikováno v:
Advances in experimental medicine and biology. 903
A limited number of studies using differing imaging approaches suggest that there are regional variation in the cerebrovascular response to hypercapnia and hypoxia. However there are limitations to these studies. In particular, it is not clear if exi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f51f9b4a775ab902826c6f61157e65a0
https://pubmed.ncbi.nlm.nih.gov/27343095
https://pubmed.ncbi.nlm.nih.gov/27343095
Autor:
Douglas R. Corfield, Leanne C. McKay
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781489976765
A limited number of studies using differing imaging approaches suggest that there are regional variation in the cerebrovascular response to hypercapnia and hypoxia. However there are limitations to these studies. In particular, it is not clear if exi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31ca8b8a43914312ee416e74ccce959b
https://doi.org/10.1007/978-1-4899-7678-9_11
https://doi.org/10.1007/978-1-4899-7678-9_11
Sub-cortical and brainstem sites associated with chemo-stimulated increases in ventilation in humans
Autor:
Leanne C. McKay, Hugo D. Critchley, Richard S.J. Frackowiak, Kevin Murphy, Douglas R. Corfield
Publikováno v:
NeuroImage. 49:2526-2535
We investigated the neural basis for spontaneous chemo-stimulated increases in ventilation in awake, healthy humans. Blood oxygen level dependent (BOLD) functional MRI was performed in nine healthy subjects using T2* weighted echo planar imaging. Bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084d4b8fcaa4bb6e34fa41d77da79fbc
https://doi.org/10.1016/j.neuroimage.2009.11.007
https://doi.org/10.1016/j.neuroimage.2009.11.007
Publikováno v:
NeuroImage. 40:1824-1832
Few tasks are simpler to perform than a breath hold; however, the neural basis underlying this voluntary inhibitory behaviour, which must suppress spontaneous respiratory motor output, is unknown. Here, using blood oxygen level-dependent functional m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056457a5953c2e3407e4992699da35f9
https://doi.org/10.1016/j.neuroimage.2008.01.058
https://doi.org/10.1016/j.neuroimage.2008.01.058
Publikováno v:
The Journal of Physiology. 557:13-18
The aim of this study was to determine if episodic hypoxia evokes persistent increases of genioglossus muscle (GG) activity, termed long-term facilitation (LTF), in neonatal rats in vivo. Experiments were performed on anaesthetized, spontaneously bre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d061be1583d85dcb11df3619bfb3c546
https://doi.org/10.1113/jphysiol.2004.064006
https://doi.org/10.1113/jphysiol.2004.064006
Autor:
Karleyton C. Evans, Lewis Adams, Richard S. J. Frackowiak, Douglas R. Corfield, Leanne C. McKay, Robert B. Banzett
Publikováno v:
Journal of Neurophysiology. 88:1500-1511
Air hunger (uncomfortable urge to breathe) is a component of dyspnea (shortness of breath). Three human H215O positron emission tomography (PET) studies have identified activation of phylogenetically ancient structures in limbic and paralimbic region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b66f4b57f37fbb2cabed2e39adc77f7
https://doi.org/10.1152/jn.2002.88.3.1500
https://doi.org/10.1152/jn.2002.88.3.1500
Publikováno v:
Nature Neuroscience. 8:1142-1144
Ablation of preBötzinger complex (preBötC) neurons, critical for respiratory rhythm generation, resulted in a progressive, increasingly severe disruption of respiratory pattern, initially during sleep and then also during wakefulness in adult rats.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f61ccb45df8b197074c159a99530237
https://doi.org/10.1038/nn1517
https://doi.org/10.1038/nn1517
Sleep represents a period of vulnerability to ventilatory irregularities, even in healthy individuals. Moreover, the presence of disease magnifies both the risk and the consequences of sleep-disordered breathing. Respiratory disorders during sleep ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1973b923a06497f6f7059f3ea89d0885
https://doi.org/10.1183/1025448x.00023909
https://doi.org/10.1183/1025448x.00023909
Autor:
Jack L. Feldman, Leanne C. McKay
Rationale: In adult rats, bilateral ablation of pre-Botzinger complex (preBotC) neurokinin 1–expressing (NK1R) neurons leads to a progressive and irreversible disruption in breathing pattern, initially during sleep, eventually resulting in an ataxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3280508d755682d6c91ae4efc915e57b
https://europepmc.org/articles/PMC2441928/
https://europepmc.org/articles/PMC2441928/
Publikováno v:
Europe PubMed Central
To investigate the functional neuroanatomy of voluntary respiratory control, blood O2 level-dependent functional magnetic resonance imaging was performed in six healthy right-handed individuals during voluntary hyperpnea. Functional images of the who
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07048037dfc55ba0fc36c4565e2d0ebe
https://pubmed.ncbi.nlm.nih.gov/12754178
https://pubmed.ncbi.nlm.nih.gov/12754178