Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Leanne B. Gasink"'
Autor:
Joseph W. Chow, Gregory G. Stone, Angela Wardman, Jie Song, Helen Broadhurst, Paul Newell, Zhangjing Chen, Leanne B. Gasink, Katrina Yates
Publikováno v:
Journal of Antimicrobial Chemotherapy. 73:2519-2523
Objectives This analysis evaluated the clinical activity of ceftazidime/avibactam against MDR Enterobacteriaceae and Pseudomonas aeruginosa isolates pooled from the adult Phase III clinical trials in patients with complicated intra-abdominal infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc443efc47adc93073dc5a61d43579f
https://doi.org/10.1093/jac/dky204
https://doi.org/10.1093/jac/dky204
Autor:
George H. Talbot, Elyse Seltzer, Thomas M. File, John Saviski, Lisa Goldberg, Wolfgang W Wicha, Leanne B. Gasink, Anita Das, Carolyn Sweeney, Steven P Gelone, Susanne Paukner
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Monotherapy with lefamulin, a novel, pleuromutilin antibiotic with intravenous and oral formulation options, was noninferior to moxifloxacin for efficacy and generally safe and well tolerated for community-acquired bacterial pneumonia (CABP). Lefamul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b3a364b61738c77e355130b4058373
https://pubmed.ncbi.nlm.nih.gov/30722059
https://pubmed.ncbi.nlm.nih.gov/30722059
Autor:
Jack D. Sobel, Leanne B. Gasink, Florian M.E. Wagenlehner, Katrina Yates, Jon Armstrong, Paul Newell, Xiangning Huang, Gregory G. Stone
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
There is an urgent need for new strategies to reduce carbapenem consumption. Ceftazidime-avibactam was highly effective for empiric treatment of complicated urinary tract infection, including in patients with ceftazidime-nonsusceptible pathogens, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8bf6a15eec729cb337531c75d68b64
https://doi.org/10.1093/cid/ciw378
https://doi.org/10.1093/cid/ciw378
Autor:
Greg Stone, Leanne B. Gasink, Angela Wardman, Paul Newell, Peter J. Laud, Jon Armstrong, Yehuda Carmeli
Publikováno v:
The Lancet Infectious Diseases. 16:661-673
Summary Background Carbapenems are frequently the last line of defence in serious infections due to multidrug-resistant Gram-negative bacteria, but their use is threatened by the growing prevalence of carbapenemase-producing pathogens. Ceftazidime-av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54ffc8f37248a44e1f10d741116e7999
https://doi.org/10.1016/s1473-3099(16)30004-4
https://doi.org/10.1016/s1473-3099(16)30004-4
Autor:
Douglas R. Rank, Jon Armstrong, Leanne B. Gasink, Jan Pachl, Helen Broadhurst, John E. Mazuski, Lily Llorens, Greg Stone, Paul Newell
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
In this randomized phase 3 trial, ceftazidime-avibactam plus metronidazole was noninferior to meropenem in treating complicated intra-abdominal infection, with similar efficacy against ceftazidime-resistant and ceftazidime-susceptible pathogens and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0071fa872a114bf623b0d915ca62ada7
http://europepmc.org/articles/PMC4872289
http://europepmc.org/articles/PMC4872289
Autor:
Thomas M File, Lisa Goldberg, Anita Das, Carolyn Sweeney, John Saviski, Steven P Gelone, Elyse Seltzer, Susanne Paukner, Wolfgang W Wicha, George H Talbot, Leanne B Gasink
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69(11)
Lefamulin, a pleuromutilin antibiotic, is active against pathogens commonly causing community-acquired bacterial pneumonia (CABP). The Lefamulin Evaluation Against Pneumonia (LEAP 1) study was a global noninferiority trial to evaluate the efficacy an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86167f4a7ce4acbb1d23687af88f3e8a
https://pubmed.ncbi.nlm.nih.gov/31822903
https://pubmed.ncbi.nlm.nih.gov/31822903
Autor:
Lisa Goldberg, Anita Das, John Saviski, George H. Talbot, Carolyn Sweeney, Elyse Seltzer, Leanne B. Gasink, Steven P Gelone, Thomas M. File, Susanne Paukner
Publikováno v:
Open Forum Infectious Diseases
Background New CABP treatments with targeted activity and improved tolerability are needed. LEF, a novel pleuromutilin antibiotic that binds to a conserved region of the bacterial ribosome, is in development for IV or oral CABP treatment. This Phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa738128fddc055d6d01a91b3179c05
https://doi.org/10.1093/ofid/ofy210.2039
https://doi.org/10.1093/ofid/ofy210.2039
Autor:
Susanne Paukner, Carolyn Sweeney, Jennifer Schranz, Lisa Goldberg, Christian Sandrock, Leanne B. Gasink, Patricia Spera, Wolfgang W Wicha, Elizabeth Alexander, Anita Das, Steven P Gelone, Gregory J. Moran
Publikováno v:
JAMA. 322:1661
Importance New antibacterials are needed to treat community-acquired bacterial pneumonia (CABP) because of growing antibacterial resistance and safety concerns with standard care. Objective To evaluate the efficacy and adverse events of a 5-day oral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39bb9b88f36663e667ee29262e4b42c
https://doi.org/10.1001/jama.2019.15468
https://doi.org/10.1001/jama.2019.15468
Autor:
P. Pfeiffenberger, Ingi Lee, Todd D. Barton, Leanne B. Gasink, D. Blyth, Emily A. Blumberg, K.D. Sims, Vivianna M. Van Deerlin
Publikováno v:
Transplant Infectious Disease. 14:149-155
Background Cytomegalovirus (CMV) disease typically occurs during the first year after solid organ transplantation, after cessation of antiviral prophylaxis. CMV occurring after the first year is uncommon and not well described. Methods We conducted a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7903aa169e8555b66987a54e9b6657
https://doi.org/10.1111/j.1399-3062.2011.00705.x
https://doi.org/10.1111/j.1399-3062.2011.00705.x
Autor:
Colleen M. Brensinger, Valerianna Amorosa, Emily A. Blumberg, Vincent Lo Re, Ingi Lee, Russell Localio, Ebbing Lautenbach, Leanne B. Gasink
Publikováno v:
The Journal of Heart and Lung Transplantation. 30:1266-1274
Background Transplant centers are reluctant to perform heart transplantation in patients with hepatitis C virus (HCV) infection because augmented immunosuppression could potentially increase mortality. However, there have been few studies examining w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033d64f9055216834d6d33a5a1c27db5
https://doi.org/10.1016/j.healun.2011.06.003
https://doi.org/10.1016/j.healun.2011.06.003