Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Leanna C. Read"'
Autor:
Anthony R. Dyer, John Boyce, George A. Burdock, Matthew C. Haas, Leanna C. Read, Richard Alsaker, Ioana G. Carabin
Publikováno v:
Food and Chemical Toxicology. 46:1659-1665
A proprietary whey growth factor extract (WGFE) or Lactermin (Lact milk; ermin growth factors) is a whey fraction of milk containing the major proteins lactoperoxidase and lactoferrin, together with a variety of minor proteins and peptides such as th
Autor:
Ross N. Butler, Julie M. Clarke, Gordon S. Howarth, Nicole C. Pelton, Leanna C. Read, Balazs Bajka
Publikováno v:
Cancer Biology & Therapy. 5:34-38
Mucositis is a debilitating side-effect of chemotherapy which affects the mucosa of the gastrointestinal tract, particularly the small intestine. Currently there are no simple, noninvasive methods to detect and monitor small intestinal function and t
Autor:
Cheryl Shoubridge, Leanna C. Read
Publikováno v:
Endocrinology. 144:1887-1893
During early postnatal development, the intestine is highly responsive to LR(3)IGF-I administration but refractory to IGF-I, in contrast to the mature intestine. Given that LR(3)IGF-I is an IGF-I analog that binds poorly to IGF binding proteins, the
Publikováno v:
Journal of Nutritional Immunology. 5:1-15
The mucosal immune response is not fully developed at birth. Maternal milk helps the neonate to adapt to an independent extrauterine life because it provides passive immunity against infections and promotes immune homeostasis against harmful immune r
Publikováno v:
Pediatric Research. 50:210-216
We determined the route of action of epidermal growth factor (EGF) [intraperitoneal (IP) versus intraamniotic administration] on adrenal development and whether its effects are mediated via the fetal hypothalamic-pituitary axis in the fetal rhesus mo
Publikováno v:
British Journal of Cancer
Chemotherapy or radiotherapy often cause mucosal damage in the gut (gut mucositis) in cancer patients. As a step to investigate mechanisms underlying subsequent intestinal repair, we have examined the expression profiles of hepatocyte growth factor (
Publikováno v:
Growth Factors. 18:119-133
Background Insulin-like growth factor-I (IGF-I) is currently under evaluation for the treatment of a variety of chronic disease conditions. We investigated the safety of long-term IGF-I administration in a rat model of inflammatory bowel disease whic
Publikováno v:
Helicobacter. 4:260-265
Background The mouse model using a human isolate of Helicobacter pylori is being widely accepted as an economical means of studying gastric infection. A noninvasive monitoring method would be useful for repeated testing to establish the time course o
Autor:
C. E. Mardell, Mary Familari, Cory J. Xian, Leanna C. Read, Johanna C. Cool, Andrew S. Giraud, Gordon S. Howarth
Publikováno v:
Europe PubMed Central
Trefoil factor TFF3 has been implicated in intestinal protection and repair. This study investigated the spatiotemporal relationship between TFF3 expression and morphological changes during intestinal damage and repair in a rat model of methotrexate-
Publikováno v:
Growth Factors. 15:279-292
We tested the ability of insulin-like growth factor-I (IGF-I) to reduce damage to the intestinal mucosa (mucositis) in rats injected with methotrexate. IGF-I was infused concurrent with methotrexate administration and compared to IGF-I administered f