Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Leandro de Rezende"'
Autor:
Erika Piccirillo, Thiago G P Alegria, Karen F Discola, José R R Cussiol, Renato M Domingos, Marcos A de Oliveira, Leandro de Rezende, Luis E S Netto, Antonia T-do Amaral
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196918 (2018)
Organic hydroperoxide resistance (Ohr) enzymes are highly efficient Cys-based peroxidases that play central roles in bacterial response to fatty acid hydroperoxides and peroxynitrite, two oxidants that are generated during host-pathogen interactions.
Externí odkaz:
https://doaj.org/article/99244d479e80482aa4aa579b00b09e4a
Autor:
Lucas G. Viviani, Erika Piccirillo, Arquimedes Cheffer, Leandro de Rezende, Henning Ulrich, Ana Maria Carmona-Ribeiro, Antonia T.-do Amaral
Publikováno v:
Molecules, Vol 23, Iss 8, p 1876 (2018)
Promiscuous inhibition due to aggregate formation has been recognized as a major concern in drug discovery campaigns. Here, we report some aggregators identified in a virtual screening (VS) protocol to search for inhibitors of human ecto-5′-nucleot
Externí odkaz:
https://doaj.org/article/2be8da1c474d48bca2d8e63868a1ffdf
Publikováno v:
Revista de Saúde Pública, Vol 31, Iss 6, Pp 545-555 (1997)
INTRODUÇÃO: O encontro de Aedes albopictus na cidade de Cananéia, região Sudeste do Estado de São Paulo, Brasil, ensejou a ocasião de realizar observações que visassem avaliar a produtividade de criadouro grande e permanente. Como objetivo, a
Externí odkaz:
https://doaj.org/article/d812390fc1a040ba9a9d0ac69a7ced6f
Autor:
Alberto Malvezzi, Patrícia M Higa, Antonia T-do Amaral, Gustavo M Silva, Fabio C Gozzo, Emer S Ferro, Leandro M Castro, Leandro de Rezende, Gisele Monteiro, Marilene Demasi
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39408 (2012)
Thimet oligopeptidase (EP24.15) is a cysteine-rich metallopeptidase containing fifteen Cys residues and no intra-protein disulfide bonds. Previous work on this enzyme revealed that the oxidative oligomerization of EP24.15 is triggered by S-glutathiol
Externí odkaz:
https://doaj.org/article/d1eb6ac02a524b949c397368b1d21451
Publikováno v:
Revista de Saúde Pública, Vol 31, Iss 6, Pp 545-555
INTRODUÇÃO: O encontro de Aedes albopictus na cidade de Cananéia, região Sudeste do Estado de São Paulo, Brasil, ensejou a ocasião de realizar observações que visassem avaliar a produtividade de criadouro grande e permanente. Como objetivo, a
Externí odkaz:
https://doaj.org/article/44c991757a1741b1bbf8a91abd0b0ab6
Autor:
Ohara Augusto, Leandro de Rezende, Alex Inague, Lucas G. Viviani, Erika Piccirillo, Marisa Helena Gennari de Medeiros, Lucas S. Dantas, Graziella E. Ronsein, Sayuri Miyamoto, Antonia Tavares do Amaral
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Unsaturated lipids are oxidized by reactive oxygen species and enzymes, leading to the increased formation of lipid hydroperoxides and several electrophilic products. Lipid-derived electrophiles can modify macromolecules, such as proteins, resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8675eb4c5dde24163fca738e69e6d46d
Autor:
Sayuri Miyamoto, Lucas G. Viviani, Alex Inague, Ohara Augusto, Leandro de Rezende, Marisa Helena Gennari de Medeiros, Lucas S. Dantas, Antonia Tavares do Amaral, Graziella E. Ronsein, Erika Piccirillo
Lipid peroxidation generates a huge number of reactive electrophilic aldehyde products. These reactive aldehydes can modify macromolecules such as proteins, resulting in loss of function and/or aggregation. The accumulation of Cu,Zn-superoxide dismut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2adce62a52aed1dbbcb00a103b4501
https://doi.org/10.1101/740688
https://doi.org/10.1101/740688
Autor:
Lucas S. Dantas, Alex Inague, Lucas G. Viviani, Leandro de Rezende, Sayuri Miyamoto, Graziella E. Ronsein, Erika Piccirillo, Ohara Augusto, Antonia Tavares do Amaral, Marisa Helena Gennari de Medeiros
Publikováno v:
Free Radical Biology and Medicine. 162:338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5d0034a45d5989e192b034eecf2d492
https://doi.org/10.1016/j.freeradbiomed.2020.10.306
https://doi.org/10.1016/j.freeradbiomed.2020.10.306
Autor:
Leandro de Rezende, Leticia Marques de Peron, Antonia Tavares do Amaral, Marcus Tullius Scotti, Hamilton Mitsugu Ishiki, Luciana Scotti
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Quantitative structure–activity relationship (QSAR) models were proposed to correlate structural features or property descriptors of compounds with their corresponding biological activities. Because of the huge number of descriptors that encode dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecebf15702e466d54f1002a4ff7f90c2
https://doi.org/10.1016/j.chemolab.2016.03.023
https://doi.org/10.1016/j.chemolab.2016.03.023
Autor:
Priscila Milani, Leandro de Rezende, Leandro H. Andrade, Marilene Demasi, Antonia Tavares do Amaral
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Amides, boronic acids and ester derivatives from L-cysteine were synthesized via a simple, short and inexpensive synthetic route, in order to achieve a novel class of inhibitors for the 20S proteasome. IC50 values of up to 52 μM were obtained with L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbf6024a8183375fde8ea1bf4e9357b
https://doi.org/10.1039/c4nj00612g
https://doi.org/10.1039/c4nj00612g