Isolation and structural characterization of bioactive compound from Aristolochia sprucei aqueous extract with anti-myotoxic activity

Autor: Isela I. González Rodríguez, Aleff F. Francisco, Leandro S. Moreira-Dill, Aristides Quintero, César L.S. Guimarães, Carlos A.H. Fernandes, Agnes A.S. Takeda, Fernando B. Zanchi, Cléopatra A.S. Caldeira, Paulo S. Pereira, Marcos R.M. Fontes, Juliana P. Zuliani, Andreimar M. Soares

Publikováno v: Toxicon: X, Vol 7, Iss , Pp 100049- (2020)

A bioactive compound isolated from the stem extract of Aristolochia sprucei through High Performance Liquid Chromatography (HPLC) was identified via Nuclear Magnetic Resonance (NMR) as the aristolochic acid (AA). This compound showed an inhibitory ef

Externí odkaz: https://doaj.org/article/340a7050427f47e2a3f687e03dfcce76

Inhibition of the Myotoxicity Induced by Bothrops jararacussu Venom and Isolated Phospholipases A2 by Specific Camelid Single-Domain Antibody Fragments.

Autor: Nidiane D R Prado, Soraya S Pereira, Michele P da Silva, Michelle S S Morais, Anderson M Kayano, Leandro S Moreira-Dill, Marcos B Luiz, Fernando B Zanchi, André L Fuly, Maribel E F Huacca, Cleberson F Fernandes, Leonardo A Calderon, Juliana P Zuliani, Luiz H Pereira da Silva, Andreimar M Soares, Rodrigo G Stabeli, Carla F C Fernandes

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0151363 (2016)

Antivenoms, produced using animal hyperimmune plasma, remains the standard therapy for snakebites. Although effective against systemic damages, conventional antivenoms have limited efficacy against local tissue damage. Additionally, the hypersensitiv

Externí odkaz: https://doaj.org/article/0a8b433c329f4416aaea944975dc51fa

Factors influencing terrestriality in primates of the Americas and Madagascar

Autor: Timothy M. Eppley, Selwyn Hoeks, Colin A. Chapman, Jörg U. Ganzhorn, Katie Hall, Megan A. Owen, Dara B. Adams, Néstor Allgas, Katherine R. Amato, McAntonin Andriamahaihavana, John F. Aristizabal, Andrea L. Baden, Michela Balestri, Adrian A. Barnett, Júlio César Bicca-Marques, Mark Bowler, Sarah A. Boyle, Meredith Brown, Damien Caillaud, Cláudia Calegaro-Marques, Christina J. Campbell, Marco Campera, Fernando A. Campos, Tatiane S. Cardoso, Xyomara Carretero-Pinzón, Jane Champion, Óscar M. Chaves, Chloe Chen-Kraus, Ian C. Colquhoun, Brittany Dean, Colin Dubrueil, Kelsey M. Ellis, Elizabeth M. Erhart, Kayley J. E. Evans, Linda M. Fedigan, Annika M. Felton, Renata G. Ferreira, Claudia Fichtel, Manuel L. Fonseca, Isadora P. Fontes, Vanessa B. Fortes, Ivanyr Fumian, Dean Gibson, Guilherme B. Guzzo, Kayla S. Hartwell, Eckhard W. Heymann, Renato R. Hilário, Sheila M. Holmes, Mitchell T. Irwin, Steig E. Johnson, Peter M. Kappeler, Elizabeth A. Kelley, Tony King, Christoph Knogge, Flávia Koch, Martin M. Kowalewski, Liselot R. Lange, M. Elise Lauterbur, Edward E. Louis, Meredith C. Lutz, Jesús Martínez, Amanda D. Melin, Fabiano R. de Melo, Tsimisento H. Mihaminekena, Monica S. Mogilewsky, Leandro S. Moreira, Letícia A. Moura, Carina B. Muhle, Mariana B. Nagy-Reis, Marilyn A. Norconk, Hugh Notman, M. Teague O’Mara, Julia Ostner, Erik R. Patel, Mary S. M. Pavelka, Braulio Pinacho-Guendulain, Leila M. Porter, Gilberto Pozo-Montuy, Becky E. Raboy, Vololonirina Rahalinarivo, Njaratiana A. Raharinoro, Zafimahery Rakotomalala, Gabriel Ramos-Fernández, Delaïd C. Rasamisoa, Jonah Ratsimbazafy, Maholy Ravaloharimanitra, Josia Razafindramanana, Tojotanjona P. Razanaparany, Nicoletta Righini, Nicola M. Robson, Jonas da Rosa Gonçalves, Justin Sanamo, Nicole Santacruz, Hiroki Sato, Michelle L. Sauther, Clara J. Scarry, Juan Carlos Serio-Silva, Sam Shanee, Poliana G. A. de Souza Lins, Andrew C. Smith, Sandra E. Smith Aguilar, João Pedro Souza-Alves, Vanessa Katherinne Stavis, Kim J. E. Steffens, Anita I. Stone, Karen B. Strier, Scott A. Suarez, Maurício Talebi, Stacey R. Tecot, M. Paula Tujague, Kim Valenta, Sarie Van Belle, Natalie Vasey, Robert B. Wallace, Gilroy Welch, Patricia C. Wright, Giuseppe Donati, Luca Santini

Publikováno v: Proceedings of the National Academy of Sciences USA, 119, 1-10
Proceedings of the National Academy of Sciences USA, 119, 42, pp. 1-10

Among mammals, the order Primates is exceptional in having a high taxonomic richness in which the taxa are arboreal, semiterrestrial, or terrestrial. Although habitual terrestriality is pervasive among the apes and African and Asian monkeys (catarrhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33a5f4f4831cd0bf9f4325e6ad6fe9c
http://hdl.handle.net/2066/287845

Gallic acid anti-myotoxic activity and mechanism of action, a snake venom phospholipase A2 toxin inhibitor, isolated from the medicinal plant Anacardium humile

Autor: Leandro S. Moreira-Dill, Carlos A.H. Fernandes, Antoniel A. S. Gomes, César L.S. Guimarães, Saulo L. da Silva, Tássia Rafaella Costa, H.C. Oliveira, Paulo Pereira, Aleff Ferreira Francisco, Marcos R.M. Fontes, Fábio F. Cardoso, Silvana Marcussi, Andreimar Martins Soares, Juliana P. Zuliani

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2022-04-28T19:41:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-31 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a943139beca3ead09a71683525ceac9

Novel camelid antibody fragments targeting recombinant nucleoprotein of Araucaria hantavirus: a prototype for an early diagnosis of Hantavirus Pulmonary Syndrome.

Autor: Soraya S Pereira, Leandro S Moreira-Dill, Michelle S S Morais, Nidiane D R Prado, Marcos L Barros, Andrea C Koishi, Giovanny A C A Mazarrotto, Giselle M Gonçalves, Juliana P Zuliani, Leonardo A Calderon, Andreimar M Soares, Luiz H Pereira da Silva, Claudia N Duarte dos Santos, Carla F C Fernandes, Rodrigo G Stabeli

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e108067 (2014)

In addition to conventional antibodies, camelids produce immunoglobulins G composed exclusively of heavy chains in which the antigen binding site is formed only by single domains called VHH. Their particular characteristics make VHHs interesting tool

Externí odkaz: https://doaj.org/article/0a08672d1450495bbcb7ef4f6f3d7921