Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Leandro H Gallo"'
Autor:
April N Meyer, Leandro H Gallo, Juyeon Ko, Guillermo Cardenas, Katelyn N Nelson, Asma Siari, Alexandre R Campos, Thomas C Whisenant, Daniel J Donoghue
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0206014 (2018)
Mutations at position K171 in the kinase activation loop of Inhibitor of κB kinase beta (IKKβ) occur in multiple myeloma, spleen marginal zone lymphoma and mantle cell lymphoma. Previously, we demonstrated that these result in constitutive kinase a
Externí odkaz:
https://doaj.org/article/7f375f0c173943949633ebeaa9b17bf7
Autor:
April N Meyer, Kristine A Drafahl, Christopher W McAndrew, Jennifer E Gilda, Leandro H Gallo, Martin Haas, Laurence M Brill, Daniel J Donoghue
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84497 (2013)
Signaling regulated by NFκB and related transcription factors is centrally important to many inflammatory and autoimmune diseases, cancer, and stress responses. The kinase that directly regulates the canonical NFκB transcriptional pathway, Inhibito
Externí odkaz:
https://doaj.org/article/94e790c838bc4b7db7445582e2055c14
Autor:
Leandro H Gallo
Publikováno v:
Oncotarget
Publikováno v:
Cytokine & Growth Factor Reviews. 26(4):425-449
The four receptor tyrosine kinases (RTKs) within the family of Fibroblast Growth Factor Receptors (FGFRs) are critical for normal development but also play an enormous role in oncogenesis. Mutations and/or abnormal expression often lead to constituti
Autor:
Martin Haas, April N. Meyer, Katelyn N. Nelson, Leandro H. Gallo, Daniel J. Donoghue, Khatereh Motamedchaboki
Publikováno v:
Cell cycle (Georgetown, Tex.), vol 13, iss 24
Cell Cycle
Cell Cycle
NFκB signaling plays a significant role in human disease, including breast and ovarian carcinoma, insulin resistance, embryonic lethality and liver degeneration, rheumatoid arthritis, aging and Multiple Myeloma (MM). Inhibitor of κB (IκB) kinase
Publikováno v:
Cell Cycle
Cell cycle (Georgetown, Tex.), vol 16, iss 7
Cell cycle (Georgetown, Tex.), vol 16, iss 7
Ubiquitination serves as a degradation mechanism of proteins, but is involved in additional cellular processes such as activation of NFκB inflammatory response and DNA damage repair. We highlight the E2 ubiquitin conjugating enzymes, E3 ubiquitin li