Zobrazeno 1 - 10 of 36 pro vyhledávání: '"Leandro Cattelan, Souza"'
1
Involvement of Indoleamine-2,3-Dioxygenase and Kynurenine Pathway in Experimental Autoimmune Encephalomyelitis in Mice
Autor: Márcia Rósula Poetini Silva, Cristiano Ricardo Jesse, Silvana Peterini Boeira, Renata Giacomeli, Micheli Stéfani Zarzecki, Leandro Cattelan Souza, Marina Prigol
Publikováno v: Neurochemical Research. 45:2959-2977
The experimental autoimmune encephalomyelitis (EAE) is a model that mimics multiple sclerosis in rodents. Evidence has suggested that the activation of indoleamine-2,3-dioxygenase (IDO), the rate-limiting enzyme in the kynurenine pathway (KP), plays
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5305cd5094cdc6e25ab19005ae5aa4
https://doi.org/10.1007/s11064-020-03144-6
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2
ORY supplementation mitigates acetaminophen-induced acute liver failure in male mice: role of oxidative stress and apoptotic markers
Autor: Leandro Cattelan Souza, André Tiago Rossito Goes, Cristiano Ricardo Jesse, Lucian Del Fabbro, Silvana Peterini Boeira, Marcelo Gomes de Gomes
Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology. 393:2129-2137
The aim of the present study was to assess the possible protective effect of γ-oryzanol (ORY) supplementation in a model of acute liver failure (ALF) induced by acetaminophen (APAP) in mice. Male Swiss strain mice were supplemented with ORY (10 and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7650526e53d06834f87a223b2cf3645a
https://doi.org/10.1007/s00210-020-01930-1
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5
Chrysin protects against behavioral, cognitive and neurochemical alterations in a 6-hydroxydopamine model of Parkinson's disease
Autor: Ana Flávia Furian, Aliny A.B. Lobo Ladd, Ricardo Vinicius Nunes Arantes, Fernando Vagner Lobo Ladd, Leandro Cattelan Souza, Cristiano Ricardo Jesse, Mauro Schneider Oliveira, Lucian Del Fabbro, Astor Reis Simionato, Silvana Peterini Boeira, André Tiago Rossito Goes, Marcelo Gomes de Gomes
Publikováno v: Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2019-10-04T19:54:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-07-27 Fundacao de apoio a pesquisa do Estado do Rio Grande do Sul (FAPERGS) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448d2cbd36ea59a520c0cce8af343212
https://doi.org/10.1016/j.neulet.2019.05.036
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6
The flavonoid chrysin protects against zearalenone induced reproductive toxicity in male mice
Autor: Cristiano Ricardo Jesse, Marcelo Gomes de Gomes, Franciele Donato, Silvana Peterini Boeira, Ana Flávia Furian, André Tiago Rossito Goes, Leandro Cattelan Souza, Lucian Del Fabbro, Carlos Borges Filho
Publikováno v: Toxicon. 165:13-21
The mycotoxin zearalenone (ZEA) has strong estrogenic effects and elicits reproductive toxicity. Chrysin is a natural flavonoid found in many plant and has a broad range of pharmacological activities, including anticancer, antioxidant and anti-inflam
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568b6fdfd3d57eb6ac01c9babb01024f
https://doi.org/10.1016/j.toxicon.2019.04.004
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7
γ-Oryzanol supplementation modifies the inflammatory and oxidative response in fulminant hepatic failure in mice
Autor: Waseem Hassan, Franciele Donato, Carlos Borges Filho, Lucian Del Fabbro, Cristiano Ricardo Jesse, Robson Luiz Puntel, Marcelo Gomes de Gomes, Matheus Chimelo Bianchini, Silvana Peterini Boeira, Leandro Cattelan Souza, André Tiago Rossito Goes
Publikováno v: PharmaNutrition. 6:191-197
The lipopolysaccharide (LPS) and d -galactosamine (D-GalN)-induced hepatotoxicity is a classical model to elucidate the mechanisms and explore potential therapeutic drugs for fulminant hepatic failure (FHF). γ-Oryzanol (γ-ORY) has been showed to po
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::18c55cf8fb43c48f44727284b5f7047f
https://doi.org/10.1016/j.phanu.2018.10.002
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8
Hesperidin protects against behavioral alterations and loss of dopaminergic neurons in 6-OHDA-lesioned mice: the role of mitochondrial dysfunction and apoptosis
Autor: Silvana Peterini Boeira, Aliny A.B. Lobo Ladd, Amanda Lopez Moreira, Michelle S. Antunes, Fernando Vagner Lobo Ladd, Leandro Cattelan Souza
Publikováno v: Metabolic brain disease. 36(1)
Hesperidin is a flavonoid glycoside that is frequently found in citrus fruits. Our group have demonstrated that hesperidin has neuroprotective effect in 6-hydroxydopamine (6-OHDA) model of Parkinson’s disease (PD), mainly by antioxidant mechanisms.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769536eb2e5f2458bad0870c18f771dc
https://pubmed.ncbi.nlm.nih.gov/33057922
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10
Dietary hydrogenated vegetable fat exacerbates the activation of kynurenine pathway caused by peripheral lipopolysaccharide immune challenge in aged mice
Autor: Franciele Donato, Robson Luiz Puntel, Lucian Del Fabbro, André Tiago Rossito Goes, Marcelo Gomes de Gomes, Silvana Peterini Boeira, Cristiano Ricardo Jesse, Carlos Borges Filho, Leandro Cattelan Souza
Publikováno v: Chemico-Biological Interactions. 293:28-37
Sickness behavior is a normal immune response of body to fight infection, accompanied by endocrine and behavioral alterations. Lipopolysaccharide (LPS) causes sickness behavior in rodents through the increase of proinflammatory cytokines, generating
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726efda751ad7c6461aef60b847d61d0
https://doi.org/10.1016/j.cbi.2018.07.023
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