Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Leandra V. Jackson"'
Autor:
Honyin Chiu, Roberta Buono, Leandra V. Jackson, Lee-or Herzog, Sharmila Mallya, Crystal S. Conn, Davide Ruggero, David A. Fruman
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102748- (2021)
Summary: The cap-binding protein eukaryotic initiation factor 4E (eIF4E) promotes translation of mRNAs associated with proliferation and survival and is an attractive target for cancer therapeutics. Here, we used Eif4e germline and conditional knocko
Externí odkaz:
https://doaj.org/article/16b020e145ba4a13bce416bb9af9a9f1
Autor:
Honyin Chiu, Sharmila Mallya, Phuongthao Nguyen, Annie Mai, Leandra V. Jackson, David G. Winkler, Jonathan P. DiNitto, Erin E. Brophy, Karen McGovern, Jeffery L. Kutok, David A. Fruman
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The class I phosphoinoside-3-kinases (PI3Ks) are important enzymes that relay signals from cell surface receptors to downstream mediators driving cellular functions. Elevated PI3K signaling is found in B cell malignancies and lymphocytes of patients
Externí odkaz:
https://doaj.org/article/b2271d917d6648c593623832e353bd28
Autor:
David A. Fruman, Lee-or Herzog, Davide Ruggero, Roberta Buono, Sharmila Mallya, Crystal S. Conn, Honyin Chiu, Leandra V. Jackson
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102748-(2021)
iScience, vol 24, iss 7
iScience
iScience, vol 24, iss 7
iScience
Summary The cap-binding protein eukaryotic initiation factor 4E (eIF4E) promotes translation of mRNAs associated with proliferation and survival and is an attractive target for cancer therapeutics. Here, we used Eif4e germline and conditional knockou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef344ac3d03875a93dccce79595b48e3
http://www.sciencedirect.com/science/article/pii/S2589004221007161
http://www.sciencedirect.com/science/article/pii/S2589004221007161
Autor:
Leandra V. Jackson, Honyin Chiu, Davide Ruggero, David A. Fruman, Annie Mai, Kwon Ik Oh, Ze'ev Ronai
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 202(2)
During an adaptive immune response, activated mature B cells give rise to Ab-secreting plasma cells to fight infection. B cells undergo Ab class switching to produce different classes of Abs with varying effector functions. The mammalian/mechanistic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bd58fcb420c01ff5cd24c3962ad779
https://pubmed.ncbi.nlm.nih.gov/30530594
https://pubmed.ncbi.nlm.nih.gov/30530594
Autor:
Ho-Jin Lee, Woochul Chang, Leandra V. Jackson, Anton M. Bennett, Hao Shi, Kisuk Min, Jae Sung Yi
The mitogen-activated protein kinases (MAPKs) have been shown to regulate skeletal muscle function. Previously, we showed that MAPK phosphatase-5 (MKP-5) negatively regulates myogenesis and regeneration of skeletal muscle through inhibition of p38 MA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76fcd4ed73cf0c26dd06ff25360b059
https://europepmc.org/articles/PMC5339744/
https://europepmc.org/articles/PMC5339744/
