Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Leander Blaas"'
Autor:
Marco Gerling, Nikè V. J. A. Büller, Leonard M. Kirn, Simon Joost, Oliver Frings, Benjamin Englert, Åsa Bergström, Raoul V. Kuiper, Leander Blaas, Mattheus C. B. Wielenga, Sven Almer, Anja A. Kühl, Erik Fredlund, Gijs R. van den Brink, Rune Toftgård
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
The Hedgehog signalling pathway can drive tumorigenesis. Here, the authors show that in a colitis-associated colon cancer model downstream Hedgehog signalling is restricted to the stroma and its over-activation can inhibit tumorigenesis, associated w
Externí odkaz:
https://doaj.org/article/3935658324894f5a9a9d4187bc7ac949
Autor:
Kashyap Dave, Inderpreet Sur, Jian Yan, Jilin Zhang, Eevi Kaasinen, Fan Zhong, Leander Blaas, Xiaoze Li, Shabnam Kharazi, Charlotte Gustafsson, Ayla De Paepe, Robert Månsson, Jussi Taipale
Publikováno v:
eLife, Vol 6 (2017)
The gene desert upstream of the MYC oncogene on chromosome 8q24 contains susceptibility loci for several major forms of human cancer. The region shows high conservation between human and mouse and contains multiple MYC enhancers that are activated in
Externí odkaz:
https://doaj.org/article/ad07a1bc56c84ce8ae8366de52425672
Publikováno v:
BioTechniques, Vol 43, Iss 5, Pp 659-664 (2007)
The use of bacterial artificial chromosomes (BACs) modified via homologous recombination in Escherichia coli has become a powerful tool in the transgenic field. Homologous recombination allows the manipulation of BACs in very different ways. However,
Externí odkaz:
https://doaj.org/article/a445b3bc623e470e96e4a199b0009c62
Autor:
Marco Gerling, Nikè V.J.A. Büller, Leonard M Kirn, Simon Joost, Oliver Frings, Benjamin Englert, Åsa Bergström, Raoul V. Kuiper, Leander Blaas, Mattheus C. B. Wielenga, Sven Almer, Anja A. Kühl, Erik Fredlund, Gijs R. van den Brink, Rune Toftgård
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-2 (2016)
Nature Communications 7:12321 doi: (2016); Published 5 Aug 2016; Updated 13 Sep 2016 In Fig. 6f of this Article, the labelling of the two immunohistochemistry images was inadvertently changed from ‘Haematoxylin, ki67’ to ‘Haematoxylin, Casp-3
Externí odkaz:
https://doaj.org/article/b0cffc70de824cc8bc75273b919c7b05
Autor:
Patricia Stiedl, Sonja M. Kessler, Leander Blaas, Michael Trauner, Mathias Müller, Emilio Casanova, Harald Esterbauer, Beatrice Grabner, Johannes Haybaeck, Martin Bilban, Gernot Zollner, Wolfgang Mikulits, Victoria Stanek, Robert McMahon, Jasmin Svinka, Thierry Claudel, Robert Eferl
Publikováno v:
Hepatology. 61:613-626
Growth hormone (GH) resistance has been associated with liver cirrhosis in humans but its contribution to the disease remains controversial. In order to elucidate whether GH resistance plays a causal role in the establishment and development of liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0c097df7ac99e4dafa9b9a98e26c5c
https://doi.org/10.1002/hep.27408
https://doi.org/10.1002/hep.27408
Publikováno v:
Protocol Exchange.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9ce13c027aeb3aaa6bb856b44dbb730
https://doi.org/10.1038/protex.2017.067
https://doi.org/10.1038/protex.2017.067
Autor:
Charlotte Gustafsson, Jussi Taipale, Shabnam Kharazi, Ayla De Paepe, Jilin Zhang, Xiaoze Li, Jian Yan, Kashyap Dave, Robert Månsson, Leander Blaas, Eevi Kaasinen, Inderpreet Sur, Fan Zhong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e04b2692a2fe87bac4d03572cf37c44e
https://doi.org/10.7554/elife.23382.029
https://doi.org/10.7554/elife.23382.029
Autor:
Ayla De Paepe, Leander Blaas, Jussi Taipale, Jian Yan, Charlotte Gustafsson, Shabnam Kharazi, Fan Zhong, Eevi Kaasinen, Robert Månsson, Jilin Zhang, Xiaoze Li, Kashyap Dave, Inderpreet Sur
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
The gene desert upstream of the MYC oncogene on chromosome 8q24 contains susceptibility loci for several major forms of human cancer. The region shows high conservation between human and mouse and contains multiple MYC enhancers that are activated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492e318ee7359c83405d30d7e123da17
https://pubmed.ncbi.nlm.nih.gov/28598326
https://pubmed.ncbi.nlm.nih.gov/28598326
Autor:
Robert Månsson, Inderpreet Sur, Xiaoze Li, Leander Blaas, Jussi Taipale, Jilin Zhang, Kashyap Dave, Jian Yan, Fan Zhong, Eevi Kaasinen
The gene desert upstream of theMyconcogene on chromosome 8q24 contains susceptibility loci for several major forms of human cancer, including cancers of breast, prostate, and colon. The region shows high conservation between human and mouse and conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d30e90d5128834aeb9e458f34c194a4b
https://doi.org/10.1101/082602
https://doi.org/10.1101/082602
Autor:
Raoul Kuiper, Simon Joost, Mattheus C. B. Wielenga, Nikè V. J. A. Büller, Anja A. Kühl, Rune Toftgård, Sven Almer, Leonard M. Kirn, Gijs R. van den Brink, Leander Blaas, Erik Fredlund, Marco Gerling, Benjamin Englert, Oliver Frings, Åsa Bergström
Publikováno v:
Nature communications, 7. Nature Publishing Group
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
A role for Hedgehog (Hh) signalling in the development of colorectal cancer (CRC) has been proposed. In CRC and other solid tumours, Hh ligands are upregulated; however, a specific Hh antagonist provided no benefit in a clinical trial. Here we use Hh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae22f9aab5aa56084e5409a70d6ebfb2
https://pure.amc.nl/en/publications/stromal-hedgehog-signalling-is-downregulated-in-colon-cancer-and-its-restoration-restrains-tumour-growth(9e612d3b-6a36-4b89-a89e-30def494510f).html
https://pure.amc.nl/en/publications/stromal-hedgehog-signalling-is-downregulated-in-colon-cancer-and-its-restoration-restrains-tumour-growth(9e612d3b-6a36-4b89-a89e-30def494510f).html