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of 8
pro vyhledávání: '"Leanda Vengethasamy"'
Autor:
Leanda Vengethasamy, Olebogeng H.I. Majane, Eugene F. du Toit, Gavin R. Norton, Angela J. Woodiwiss
Publikováno v:
SA Heart Journal, Vol 6, Iss 3, Pp 154-160 (2017)
Although obesity is an independent risk factor for heart failure and even mild-to-moderate forms of obesity are associated with myocardial systolic dysfunction the mechanisms of the myocardial dysfunction have not been identified. We assessed whether
Externí odkaz:
https://doaj.org/article/d7fd4aa7ca054bb3814cdbabedb2a5c4
Autor:
Olebogeng H.I. Majane, Angela J. Woodiwiss, Eugene F. Du Toit, Leanda Vengethasamy, Gavin R. Norton
Publikováno v:
SA Heart Journal, Vol 6, Iss 3, Pp 154-160 (2017)
Although obesity is an independent risk factor for heart failure and even mild-to-moderate forms of obesity are associated with myocardial systolic dysfunction the mechanisms of the myocardial dysfunction have not been identifi ed. We assessed whethe
Autor:
Ricard Farre Marti, Rik Gijsbers, Birger Tielemans, Marion Delcroix, Leanda Vengethasamy, Catharina Belge, Allard Wagenaar, Rozenn Quarck, Annelies Michiels
Publikováno v:
4.3 Pulmonary Circulation and Pulmonary Vascular Diseases.
Mutations in the bone morphogenetic protein receptor 2 ( BMPR2 ) gene are associated with heritable pulmonary arterial hypertension (PAH). In addition, BMPRII signalling is impaired in idiopathic PAH. Since BMPR2 mutation carriers do not all develop
Autor:
Marion Delcroix, Aurélie Hautefort, Leanda Vengethasamy, Rozenn Quarck, Catharina Belge, Birger Tielemans, Frédéric Perros, Stijn E. Verleden, Dirk Van Raemdonck, Elie Fadel
Publikováno v:
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Mutations in the bone morphogenetic protein receptor (BMPR2) gene have been observed in 70 % of patients with heritable pulmonary arterial hypertension (HPAH) and in 11-40 % with idiopathic PAH (IPAH). However, carriers of a BMPR2 mutation have only
Autor:
Pinhas Sareli, Margaret Badenhorst, Janice Paiker, Frederic S. Michel, Angela J. Woodiwiss, Muzi J. Maseko, Olebogeng H.I. Majane, Leanda Vengethasamy, Gavin R. Norton
Publikováno v:
Hypertension. 59:62-69
In high-Na + , low-K + diets, which suppress renin release in salt-sensitive groups, the mechanisms maintaining increases in renin-angiotensin-aldosterone system activation downstream from renin and renin-angiotensin-aldosterone system–induced effe
Autor:
Pinhas Sareli, Muzi J. Maseko, Angela J. Woodiwiss, Leanda Vengethasamy, Olebogeng H.I. Majane, Gavin R. Norton, Leon Scott, Michelle Redelinghuys
Publikováno v:
Journal of Hypertension. 29:854-862
Objectives As the impact of mild smoking on blood pressure (BP) is uncertain, we assessed the relationship between predominantly mild current smoking and out-of-office BP and the effect of angiotensin-converting enzyme (ACE) genotype on this relation
Autor:
Angela J. Woodiwiss, Olebogeng H.I. Majane, Siyanda Makaula, Leanda Vengethasamy, Gavin R. Norton, Eugene F. Du Toit
Publikováno v:
Hypertension. 54:1376-1383
We explored whether dietary-induced obesity hastens the transition from concentric left ventricular (LV) hypertrophy to pump dysfunction in spontaneously hypertensive rats (SHRs) and the mechanisms thereof. After feeding rats a diet for 4 to 5 months
Autor:
Leanda Vengethasamy, Marijke Wynants, Bart Meyns, Marion Delcroix, Alicja Ronisz, Rozenn Quarck
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 305(12)
Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by thrombofibrotic obstruction of proximal pulmonary arteries. The cellular and molecular mechanisms underlying the pathogenesis remain incompletely understood, although we recent