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FMRP activity and control of Csw/SHP2 translation regulate MAPK-dependent synaptic transmission.

Autor: Leahy, Shannon N.¹ (AUTHOR), Song, Chunzhu¹ (AUTHOR), Vita, Dominic J.¹ (AUTHOR), Broadie, Kendal^1,2,3,4 (AUTHOR) kendal.broadie@vanderbilt.edu

Publikováno v: PLoS Biology. 1/26/2023, Vol. 21 Issue 1, p1-31. 31p. 3 Charts, 5 Graphs.

RNA-binding FMRP and Staufen sequentially regulate the Coracle scaffold to control synaptic glutamate receptor and bouton development.

Autor: Chunzhu Song, Leahy, Shannon N., Rushton, Emma M., Broadie, Kendal

Publikováno v: Development (09501991); May2022, Vol. 149 Issue 9, p1-16, 16p

Muscle cofilin alters neuromuscular junction postsynaptic development to strengthen functional neurotransmission.

Autor: Christophers B; Weill Cornell-Rockefeller-Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, 10065, USA.; Biochemistry, Cell & Developmental Biology, and Molecular Biology (BCMB) program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA.; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering, Cancer Center, New York, NY 10065, USA., Leahy SN; Department of Biological Sciences, Vanderbilt University and Medical Center, Nashville, TN 37235, USA., Soffar DB; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering, Cancer Center, New York, NY 10065, USA., von Saucken VE; Weill Cornell-Rockefeller-Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, 10065, USA.; Biochemistry, Cell & Developmental Biology, and Molecular Biology (BCMB) program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA.; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering, Cancer Center, New York, NY 10065, USA., Broadie K; Department of Biological Sciences, Vanderbilt University and Medical Center, Nashville, TN 37235, USA.; Kennedy Center for Research on Human Development, Vanderbilt University and Medical Center, Nashville, TN 37235, USA.; Vanderbilt Brain Institute, Vanderbilt University and Medical Center, Nashville, TN 37235, USA., Baylies MK; Biochemistry, Cell & Developmental Biology, and Molecular Biology (BCMB) program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA.; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering, Cancer Center, New York, NY 10065, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 22. Date of Electronic Publication: 2023 Nov 22.