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Autor:
Stephanie Wilt, Leah Valencia, Taylor Quintana, Bruce D. Hammock, Paula K. Hudson, Stephanie Sanchez, Sean D. Kodani, Christophe Morisseau, Stevan Pecic, Ram Kandasamy
Publikováno v:
Bioorg Med Chem
Fatty acid amide hydrolase (FAAH) is a membrane protein that hydrolyzes endocannabinoids, and its inhibition produces analgesic and anti-inflammatory effects. The soluble epoxide hydrolase (sEH) hydrolyzes epoxyeicosatrienoic acids (EETs) to dihydrox