Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Leah N. Cardwell"'
Autor:
David Porciani, Leah N. Cardwell, Kwaku D. Tawiah, Khalid K. Alam, Margaret J. Lange, Mark A. Daniels, Donald H. Burke
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Large RNAs and ribonucleoprotein complexes have shown potential as novel therapeutic agents, but their targeted delivery to cells is still challenging. Here the authors present a modular aptamer nanostructure for intracellular delivery of RNAs up to
Externí odkaz:
https://doaj.org/article/ffee912c372c4f2bb7d08733a0e28329
Autor:
Bret D. Ulery, Fabio Gallazzi, Mark A. Daniels, David Porciani, Megan C. Schulte, Andrea Nolla, Josiah D. Smith, Donald H. Burke, Leah N. Cardwell, Brenna T. Cornelison
Publikováno v:
Molecular Systems Design & Engineering. 5:269-283
Peptide amphiphile micelles (PAMs) are a powerful platform technology for improving the delivery of therapeutic and prophylactic peptides. While previous research has shown aptamer-displaying PAMs enhance cell association, transportation to intracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::426493641bcd07cec23d7ac649893872
https://doi.org/10.1039/c9me00092e
https://doi.org/10.1039/c9me00092e
Autor:
Julie A Nguyen, Mark A. Daniels, Josiah D. Smith, Aiden C. Ellis, Joe E. Anderson, Rama Rao Tata, Megan C. Schulte, Evan T. Schoenherr, Bret D. Ulery, David Porciani, Donald H. Burke, Leah N. Cardwell, Andrew J. Greenwald, Gracen F. Seim, Xiaofei Wang, Margaret J. Lange
Poly(amino acid)s are a diverse and capable class of polymers with significant potential for utilization in a wide variety of drug delivery applications. A sub-class of these biomaterials known as lipidated poly(amino acid)s (LPAAs) are amphiphiles c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3e9f0be8f978d1accbb8c9d7d77f0e
Autor:
Brian K. Weaver, Leah N. Cardwell
Publikováno v:
Advances in Biological Chemistry. :261-273
Interleukin-10 (IL-10) mediates an anti-inflammatory response that constrains immune responses and limits inflammation-associated pathology. IL-10 does so, in part, by selectively inhibiting pro-inflammatory cytokine and chemokine expression induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0001cc8cd22f288668233e226b605ff
https://doi.org/10.4236/abc.2014.44032
https://doi.org/10.4236/abc.2014.44032
Autor:
Brian K. Weaver, Brian A. Peterson, Maxwell A. Sickman, Brad D. Groppe, Amanda F. Dillow, Tyler J. Smith, Leah N. Cardwell
Publikováno v:
Open Journal of Immunology. :96-116
Interleukin-10 (IL-10) mediates an anti-inflammatory response that is executed through the expression of IL-10-induced genes. Certain IL-10-induced genes, exemplified by TNIP3, are induced by IL-10 only in conjunction with a pro-inflammatory signal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07587bc8290c875aeeb4bc1d84e3b3e9
https://doi.org/10.4236/oji.2014.43013
https://doi.org/10.4236/oji.2014.43013
The scaffold molecule POSH is crucial for the regulation of proliferation and effector function in CD8+ T cells. However, its role in CD4+ T cells is not known. In this study, we found that disruption of the POSH scaffold complex established a transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d84b7accb3020f84675599b3b952483
https://europepmc.org/articles/PMC4868786/
https://europepmc.org/articles/PMC4868786/
Autor:
Julie A Nguyen, David Porciani, Leah N. Cardwell, Donald H. Burke, Josiah D. Smith, Bret D. Ulery, Mark A. Daniels, Fabio Gallazzi, Rama Rao Tata, Rui Zhang
Publikováno v:
Physical Biology. 15:065006
Peptide amphiphile micelles (PAMs) are attractive vehicles for the delivery of a variety of therapeutic and prophylactic peptides. However, a key limitation of PAMs is their lack of preferential targeting ability. In this paper, we describe our desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebd2233c2d1cc3a5fa1711cde921245
https://doi.org/10.1088/1478-3975/aadb68
https://doi.org/10.1088/1478-3975/aadb68
Autor:
Josiah D Smith, Leah N Cardwell, David Porciani, Julie A Nguyen, Rui Zhang, Fabio Gallazzi, Rama Rao Tata, Donald H Burke, Mark A Daniels, Bret D Ulery
Publikováno v:
Physical Biology; Nov2018, Vol. 15 Issue 6, p1-1, 1p