Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Leah M. Seebald"'
Publikováno v:
ACS Chem Biol
Monotopic phosphoglycosyl transferase enzymes (MonoPGTs) initiate the assembly of prokaryotic glycoconjugates essential for bacterial survival and proliferation. MonoPGTs belong to an expansive superfamily with a diverse and richly annotated sequence
Autor:
Leah M. Seebald, Christopher M. DeMott, Srivathsan Ranganathan, Papa Nii Asare-Okai, Anastasia Glazunova, Alan Chen, Alexander Shekhtman, Maksim Royzen
Publikováno v:
Journal of Inorganic Biochemistry. 170:202-208
Paramagnetic resonance enhancement (PRE) is an NMR technique that allows studying three-dimensional structures of RNA-protein complexes in solution. RNA strands are typically spin labeled using nitroxide reagents, which provide minimal perturbation t
Autor:
Christopher M. DeMott, Alexander Shekhtman, Alan A. Chen, Leah M. Seebald, Papa Nii Asare-Okai, Srivathsan V. Ranganathan, Maksim Royzen, Anastasia Glazunova
Publikováno v:
Inorganic Chemistry. 56:3773-3780
Paramagnetic NMR techniques allow for studying three-dimensional structures of RNA–protein complexes. In particular, paramagnetic relaxation enhancement (PRE) data can provide valuable information about long-range distances between different struct
Publikováno v:
ACS Central Science
ACS Central Science, Vol 2, Iss 7, Pp 476-482 (2016)
ACS Central Science, Vol 2, Iss 7, Pp 476-482 (2016)
The ability to activate drugs only at desired locations avoiding systemic immunosuppression and other dose limiting toxicities is highly desirable. Here we present a new approach, named local drug activation, that uses bioorthogonal chemistry to conc